AutismKB 2.0

Annotation Detail for SFTPC


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Basic Information Top
Gene Symbol:SFTPC ( PSP-C,SFTP2,SMDP2,SP-C )
Gene Full Name: surfactant protein C
Band: 8p21.3
Quick LinksEntrez ID:6440; OMIM: 178620; Uniprot ID:PSPC_HUMAN; ENSEMBL ID: ENSG00000168484; HGNC ID: 10802
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus63 / 564012111
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult520 / 1939121268
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma256 / 828233090
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor45 / 103127436
lymphoma0 / 717550 
non-neoplasia91 / 97250935
normal430 / 3360307127
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue256 / 1492551715
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart16 / 89626178
intestine4 / 23447217
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung544 / 3369741614
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 38691_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts3.25
Adipocyte2.55
AdrenalCortex2.55
Adrenalgland2.15
Amygdala2.75
Appendix2.6
AtrioventricularNode1.9
BDCA4+_DentriticCells2.9
Bonemarrow2.5
BronchialEpithelialCells2.55
CD105+_Endothelial2.55
CD14+_Monocytes2.8
CD19+_BCells(neg._sel.)2.75
CD33+_Myeloid3.3
CD34+3.3
CD4+_Tcells2.85
CD56+_NKCells3.1
CD71+_EarlyErythroid2.35
CD8+_Tcells2.5
CardiacMyocytes3.35
Caudatenucleus2.3
Cerebellum2.05
CerebellumPeduncles3.05
CiliaryGanglion1.75
CingulateCortex2.65
Colorectaladenocarcinoma2.8
DorsalRootGanglion1.9
FetalThyroid2.45
Fetalbrain2.55
Fetalliver2.2
Fetallung4302.25
GlobusPallidus1.85
Heart3.7
Hypothalamus3
Kidney2
Leukemia_chronicMyelogenousK-5622.35
Leukemia_promyelocytic-HL-602.25
Leukemialymphoblastic(MOLT-4)2.1
Liver9.65
Lung16081.5
Lymphnode15.35
Lymphoma_burkitts(Daudi)3.2
Lymphoma_burkitts(Raji)3.9
MedullaOblongata2.4
OccipitalLobe2.7
OlfactoryBulb2
Ovary1.7
Pancreas16.45
PancreaticIslet2.75
ParietalLobe2.6
Pituitary4.2
Placenta5.5
Pons2.45
PrefrontalCortex4.35
Prostate3.65
Salivarygland2
SkeletalMuscle3
Skin2
SmoothMuscle2.95
Spinalcord2.75
SubthalamicNucleus2.4
SuperiorCervicalGanglion2.85
TemporalLobe2.4
Testis2.25
TestisGermCell2.15
TestisIntersitial2.15
TestisLeydigCell2.5
TestisSeminiferousTubule2.2
Thalamus2.6
Thymus2.05
Thyroid5
Tongue2.45
Tonsil2.5
Trachea2.15
TrigeminalGanglion2.55
Uterus2.2
UterusCorpus2.35
WholeBlood2.85
Wholebrain4.45
colon2.6
pineal_day3.18
pineal_night3.1
retina3.475
small_intestine2.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P250666
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.41 ± 0.53
Basal Forebrain5.39 ± 0.21
Basal Part of Pons5.23 ± 0.24
Cerebellar Cortex5.01 ± 0.33
Cerebellar Nuclei5.55 ± 0.6
Claustrum5.64 ± 0.65
Epithalamus5.89 ± 0.7
Frontal Lobe5.33 ± 0.42
Globus Pallidus6.19 ± 0.32
Hypothalamus5.25 ± 0.69
Insula5.05 ± 0.37
Limbic Lobe5.23 ± 0.45
Mesencephalon5.43 ± 0.42
Myelencephalon5.47 ± 0.49
Occipital Lobe5.28 ± 0.53
Parietal Lobe5.35 ± 0.38
Pontine Tegmentum5.19 ± 0.51
Striatum5.57 ± 0.39
Subthalamus5.5 ± 0.09
Temporal Lobe5.2 ± 0.48
Thalamus5.35 ± 0.38
White Matter6.61 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
SftpcCBCerebellum4.44
5.35
SftpcCTXCerebral cortex3.43
2.65
SftpcHIPHippocampal region1.07
1.04
SftpcHPFHippocampal formation1.46
1.38
SftpcHYHypothalamus1.44
1.67
SftpcLSXLateral septal complex0.64
0.45
SftpcMBMidbrain1.85
2.12
SftpcMYMedulla6.21
7.61
SftpcOLFOlfactory bulb5.64
3.96
SftpcPPons3.04
3.37
SftpcPALPallidum2.15
2.47
SftpcRHPRetrohippocampal region2.1
1.82
SftpcsAMYStriatum-like amygdalar nuclei0.88
0.66
SftpcSTRStriatum1.19
1.06
SftpcSTRdStriatum dorsal region0.93
0.93
SftpcSTRvStriatum ventral region2.35
1.81
SftpcTHThalamus0.98
0.89
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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