AutismKB 2.0

Annotation Detail for SFTPD


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Basic Information Top
Gene Symbol:SFTPD ( COLEC7,PSP-D,SFTP4,SP-D )
Gene Full Name: surfactant protein D
Band: 10q22.3
Quick LinksEntrez ID:6441; OMIM: 178635; Uniprot ID:SFTPD_HUMAN; ENSEMBL ID: ENSG00000133661; HGNC ID: 10803
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal31 / 33603079
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx1 / 2414541
liver0 / 2077430 
lung27 / 33697480
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214199_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.1
Adipocyte5.3
AdrenalCortex5.7
Adrenalgland4.45
Amygdala5.55
Appendix5.35
AtrioventricularNode4.75
BDCA4+_DentriticCells5.55
Bonemarrow5.25
BronchialEpithelialCells5.15
CD105+_Endothelial5.35
CD14+_Monocytes5.65
CD19+_BCells(neg._sel.)5.5
CD33+_Myeloid7.05
CD34+6.55
CD4+_Tcells5.55
CD56+_NKCells6.4
CD71+_EarlyErythroid4.95
CD8+_Tcells4.85
CardiacMyocytes7.35
Caudatenucleus4.65
Cerebellum4.2
CerebellumPeduncles5.95
CiliaryGanglion3.95
CingulateCortex5.3
Colorectaladenocarcinoma5.25
DorsalRootGanglion6.25
FetalThyroid5.1
Fetalbrain5.2
Fetalliver4.55
Fetallung40.45
GlobusPallidus5.6
Heart6.9
Hypothalamus5.75
Kidney4.35
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.6
Leukemialymphoblastic(MOLT-4)4.15
Liver7
Lung2188.55
Lymphnode4.55
Lymphoma_burkitts(Daudi)6.7
Lymphoma_burkitts(Raji)7.65
MedullaOblongata4.8
OccipitalLobe4.7
OlfactoryBulb4.15
Ovary3.5
Pancreas4.25
PancreaticIslet5.65
ParietalLobe5.6
Pituitary6.7
Placenta5.4
Pons5
PrefrontalCortex6.35
Prostate6.2
Salivarygland4.2
SkeletalMuscle6.4
Skin4.35
SmoothMuscle5.9
Spinalcord5.6
SubthalamicNucleus4.9
SuperiorCervicalGanglion6.3
TemporalLobe4.8
Testis4.5
TestisGermCell4.2
TestisIntersitial4.4
TestisLeydigCell5.2
TestisSeminiferousTubule4.45
Thalamus5.35
Thymus4.05
Thyroid7.4
Tongue5.15
Tonsil5.1
Trachea4.4
TrigeminalGanglion5.5
Uterus4.4
UterusCorpus4.9
WholeBlood5.55
Wholebrain4.25
colon5.25
pineal_day8.66
pineal_night8.24
retina6.3
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15171_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.15 ± 0.65
Basal Forebrain2.78 ± 0.43
Basal Part of Pons3.27 ± 0.34
Cerebellar Cortex3.02 ± 0.5
Cerebellar Nuclei3.01 ± 0.36
Claustrum2.87 ± 0.72
Epithalamus3.72 ± 0.69
Frontal Lobe3.26 ± 0.5
Globus Pallidus2.65 ± 0.57
Hypothalamus3.14 ± 0.41
Insula3.3 ± 0.31
Limbic Lobe3.08 ± 0.6
Mesencephalon3.22 ± 0.57
Myelencephalon3.11 ± 0.58
Occipital Lobe2.72 ± 0.59
Parietal Lobe3.03 ± 0.48
Pontine Tegmentum3.04 ± 0.59
Striatum3.25 ± 0.6
Subthalamus3.1 ± 0.85
Temporal Lobe3.25 ± 0.53
Thalamus3.01 ± 0.53
White Matter2.21 ± 0.5
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00035471 14 250 263 KVELFPNGQSVGEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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