AutismKB 2.0

Annotation Detail for ARAP3


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Basic Information Top
Gene Symbol:ARAP3 ( CENTD3,DRAG1,FLJ21065 )
Gene Full Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Band: 5q31.3
Quick LinksEntrez ID:64411; OMIM: 606647; Uniprot ID:ARAP3_HUMAN; ENSEMBL ID: ENSG00000120318; HGNC ID: 24097
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor10 / 26384537
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal88 / 336030726
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone1 / 7165513
bone marrow2 / 4880140
brain23 / 110098920
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye9 / 21105442
heart3 / 8962633
intestine5 / 23447221
kidney5 / 21177723
larynx0 / 241450 
liver4 / 20774319
lung11 / 33697432
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth1 / 6705214
muscle6 / 10771555
nerve0 / 157680 
ovary4 / 10205139
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta7 / 28082524
prostate2 / 18934510
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach1 / 9661910
testis4 / 33044212
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus6 / 23287825
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218950_at
Cell line Expression level Expression bar
721_B_lymphoblasts19.6
Adipocyte17.8
AdrenalCortex18.35
Adrenalgland15
Amygdala18.95
Appendix18
AtrioventricularNode13.65
BDCA4+_DentriticCells18.65
Bonemarrow17.85
BronchialEpithelialCells17.8
CD105+_Endothelial18.2
CD14+_Monocytes31.6
CD19+_BCells(neg._sel.)18.15
CD33+_Myeloid37.85
CD34+21.7
CD4+_Tcells17.95
CD56+_NKCells21.65
CD71+_EarlyErythroid15.9
CD8+_Tcells15.6
CardiacMyocytes22.9
Caudatenucleus16.1
Cerebellum14.5
CerebellumPeduncles22.35
CiliaryGanglion12.75
CingulateCortex18.25
Colorectaladenocarcinoma19.65
DorsalRootGanglion13.75
FetalThyroid18
Fetalbrain18.05
Fetalliver15.55
Fetallung21.65
GlobusPallidus13
Heart24.8
Hypothalamus19.6
Kidney14.55
Leukemia_chronicMyelogenousK-56216.65
Leukemia_promyelocytic-HL-6014.8
Leukemialymphoblastic(MOLT-4)14.3
Liver23.85
Lung32.7
Lymphnode16.75
Lymphoma_burkitts(Daudi)22.8
Lymphoma_burkitts(Raji)24.65
MedullaOblongata16.45
OccipitalLobe15.6
OlfactoryBulb14.2
Ovary11.85
Pancreas13.95
PancreaticIslet19.2
ParietalLobe18.7
Pituitary21
Placenta23.85
Pons17
PrefrontalCortex22.5
Prostate22.6
Salivarygland14.15
SkeletalMuscle26.5
Skin13.75
SmoothMuscle23.75
Spinalcord19.25
SubthalamicNucleus16.35
SuperiorCervicalGanglion22.1
TemporalLobe16.35
Testis14.55
TestisGermCell14.65
TestisIntersitial14.7
TestisLeydigCell17.7
TestisSeminiferousTubule15.45
Thalamus18.2
Thymus14.3
Thyroid24.05
Tongue17.5
Tonsil17.5
Trachea15.2
TrigeminalGanglion26.8
Uterus15.85
UterusCorpus19.75
WholeBlood167.3
Wholebrain15.35
colon17.7
pineal_day21.78
pineal_night20.56
retina21.9
small_intestine16.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6978_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.07 ± 1.12
Basal Forebrain1.53 ± 0.2
Basal Part of Pons1.29 ± 0.56
Cerebellar Cortex1.66 ± 0.96
Cerebellar Nuclei1.99 ± 0.89
Claustrum2.32 ± 0.76
Epithalamus1.25 ± 0.71
Frontal Lobe1.45 ± 0.71
Globus Pallidus2.11 ± 0.86
Hypothalamus1.59 ± 0.71
Insula1.31 ± 0.46
Limbic Lobe1.56 ± 0.69
Mesencephalon1.74 ± 0.71
Myelencephalon1.61 ± 0.68
Occipital Lobe1.63 ± 0.74
Parietal Lobe1.58 ± 0.78
Pontine Tegmentum1.69 ± 0.76
Striatum1.6 ± 0.49
Subthalamus1.71 ± 0.62
Temporal Lobe1.55 ± 0.68
Thalamus1.59 ± 0.59
White Matter1.97 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Centd3CBCerebellum58.61
87.42
Centd3CTXCerebral cortex90.62
70.55
Centd3HIPHippocampal region55.76
84.04
Centd3HPFHippocampal formation64.75
77.25
Centd3HYHypothalamus48.15
38.91
Centd3LSXLateral septal complex36.62
26.87
Centd3MBMidbrain62.17
55.11
Centd3MYMedulla65.31
70.54
Centd3OLFOlfactory bulb84.24
80.08
Centd3PPons55.69
56.86
Centd3PALPallidum58.07
50.22
Centd3RHPRetrohippocampal region83.28
71.8
Centd3sAMYStriatum-like amygdalar nuclei57.96
41.38
Centd3STRStriatum66.17
49.01
Centd3STRdStriatum dorsal region70.39
52.8
Centd3STRvStriatum ventral region68.2
49.48
Centd3THThalamus74.45
66.44
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00037919 20 1453 1472 SSTLGQEERPPEPPPGPPSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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