AutismKB 2.0

Annotation Detail for DCLRE1C


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Basic Information Top
Gene Symbol:DCLRE1C ( A-SCID,DCLREC1C,FLJ11360,FLJ36438,RS-SCID,SCIDA,SNM1C,hSNM1C )
Gene Full Name: DNA cross-link repair 1C
Band: 10p13
Quick LinksEntrez ID:64421; OMIM: 605988; Uniprot ID:DCR1C_HUMAN; ENSEMBL ID: ENSG00000152457; HGNC ID: 17642
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus26 / 56401246
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia7 / 9584273
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal101 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood7 / 12347856
bone0 / 716550 
bone marrow1 / 4880120
brain21 / 110098919
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye6 / 21105428
heart2 / 8962622
intestine7 / 23447229
kidney8 / 21177737
larynx2 / 2414582
liver1 / 2077434
lung10 / 33697429
lymph0 / 442700 
lymph node12 / 91610130
mammary gland1 / 1532716
mouth4 / 6705259
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta7 / 28082524
prostate5 / 18934526
salivary gland0 / 201550 
skin4 / 21057418
spleen2 / 5395237
stomach0 / 966190 
testis3 / 3304429
thymus5 / 8113161
thyroid0 / 474730 
tonsil2 / 16999117
trachea1 / 5241319
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219678_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts89.05
Adipocyte19.65
AdrenalCortex52.2
Adrenalgland18.7
Amygdala27.3
Appendix30.4
AtrioventricularNode47.5
BDCA4+_DentriticCells50.7
Bonemarrow22.65
BronchialEpithelialCells16.8
CD105+_Endothelial92.25
CD14+_Monocytes43.7
CD19+_BCells(neg._sel.)147.15
CD33+_Myeloid93.7
CD34+88.3
CD4+_Tcells82.2
CD56+_NKCells63.85
CD71+_EarlyErythroid62.1
CD8+_Tcells100.65
CardiacMyocytes28.45
Caudatenucleus20.85
Cerebellum17.15
CerebellumPeduncles30.35
CiliaryGanglion23.55
CingulateCortex24.3
Colorectaladenocarcinoma31.15
DorsalRootGanglion40.8
FetalThyroid24.8
Fetalbrain28.05
Fetalliver18.6
Fetallung20.95
GlobusPallidus21.25
Heart27.15
Hypothalamus23.9
Kidney18.6
Leukemia_chronicMyelogenousK-56224.1
Leukemia_promyelocytic-HL-6019.55
Leukemialymphoblastic(MOLT-4)19.4
Liver28.55
Lung21.4
Lymphnode22.1
Lymphoma_burkitts(Daudi)32.8
Lymphoma_burkitts(Raji)52.4
MedullaOblongata25.8
OccipitalLobe38.7
OlfactoryBulb35.6
Ovary15.8
Pancreas25.45
PancreaticIslet31.3
ParietalLobe27.75
Pituitary28.65
Placenta22.7
Pons36.65
PrefrontalCortex49.8
Prostate45.65
Salivarygland18.35
SkeletalMuscle28.25
Skin50.05
SmoothMuscle20.05
Spinalcord21.7
SubthalamicNucleus29.95
SuperiorCervicalGanglion61.25
TemporalLobe22.25
Testis17.05
TestisGermCell28.3
TestisIntersitial23.8
TestisLeydigCell27.6
TestisSeminiferousTubule20.95
Thalamus23.9
Thymus22.4
Thyroid40.35
Tongue46.35
Tonsil54.75
Trachea19.7
TrigeminalGanglion62.2
Uterus43.45
UterusCorpus21.1
WholeBlood17.55
Wholebrain16.4
colon32.05
pineal_day59.96
pineal_night63.96
retina31.325
small_intestine26.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P86635
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.16 ± 0.54
Basal Forebrain4.23 ± 0.29
Basal Part of Pons3.99 ± 0.64
Cerebellar Cortex4.34 ± 0.32
Cerebellar Nuclei4.22 ± 0.46
Claustrum4.09 ± 1.02
Epithalamus4.52 ± 0.29
Frontal Lobe3.99 ± 0.43
Globus Pallidus4.74 ± 0.37
Hypothalamus3.92 ± 0.39
Insula3.99 ± 0.44
Limbic Lobe4.04 ± 0.55
Mesencephalon4.25 ± 0.57
Myelencephalon4.12 ± 0.48
Occipital Lobe4.56 ± 0.57
Parietal Lobe4.1 ± 0.45
Pontine Tegmentum4.15 ± 0.51
Striatum4.09 ± 0.5
Subthalamus4.02 ± 0.28
Temporal Lobe3.99 ± 0.48
Thalamus4.13 ± 0.43
White Matter5.07 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dclre1cCBCerebellum1.37
1.83
Dclre1cCTXCerebral cortex1.86
1.78
Dclre1cHIPHippocampal region2.99
2.65
Dclre1cHPFHippocampal formation2.38
2.02
Dclre1cHYHypothalamus0.28
0.24
Dclre1cLSXLateral septal complex0.61
0.53
Dclre1cMBMidbrain1.64
2.26
Dclre1cMYMedulla1.04
1.27
Dclre1cOLFOlfactory bulb2.03
3.3
Dclre1cPPons0.54
0.58
Dclre1cPALPallidum0.3
0.31
Dclre1cRHPRetrohippocampal region1.28
1.09
Dclre1csAMYStriatum-like amygdalar nuclei1.53
1.15
Dclre1cSTRStriatum0.59
0.55
Dclre1cSTRdStriatum dorsal region0.49
0.51
Dclre1cSTRvStriatum ventral region0.26
0.23
Dclre1cTHThalamus0.97
0.91
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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