AutismKB 2.0

Annotation Detail for NARFL


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Basic Information Top
Gene Symbol:NARFL ( FLJ21988,HPRN,IOP1,LET1L,PRN )
Gene Full Name: nuclear prelamin A recognition factor-like
Band: 16p13.3
Quick LinksEntrez ID:64428; OMIM: 611118; Uniprot ID:NARFL_HUMAN; ENSEMBL ID: ENSG00000103245; HGNC ID: 14179
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus25 / 56401244
neonate0 / 310970 
infant2 / 2362084
juvenile5 / 5555689
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor17 / 26384564
glioma7 / 10688365
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia9 / 9584293
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma5 / 7175569
non-neoplasia5 / 9725051
normal176 / 336030752
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer9 / 10268087
retinoblastoma0 / 463560 
skin tumor9 / 12494972
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland4 / 33197120
ascites2 / 4001549
bladder0 / 297570 
blood5 / 12347840
bone2 / 7165527
bone marrow2 / 4880140
brain100 / 110098990
cervix8 / 48171166
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye7 / 21105433
heart7 / 8962678
intestine14 / 23447259
kidney13 / 21177761
larynx0 / 241450 
liver5 / 20774324
lung5 / 33697414
lymph1 / 4427022
lymph node4 / 9161043
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary2 / 10205119
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta14 / 28082549
prostate17 / 18934589
salivary gland2 / 2015599
skin10 / 21057447
spleen8 / 53952148
stomach3 / 9661931
testis12 / 33044236
thymus13 / 81131160
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218742_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.65
Adipocyte6.15
AdrenalCortex6.85
Adrenalgland5.3
Amygdala6.3
Appendix5.8
AtrioventricularNode4.55
BDCA4+_DentriticCells7.45
Bonemarrow6.15
BronchialEpithelialCells6.15
CD105+_Endothelial7.65
CD14+_Monocytes6.9
CD19+_BCells(neg._sel.)6.9
CD33+_Myeloid8.05
CD34+9.15
CD4+_Tcells8.15
CD56+_NKCells7.55
CD71+_EarlyErythroid5.75
CD8+_Tcells6.15
CardiacMyocytes7.65
Caudatenucleus5.6
Cerebellum5.1
CerebellumPeduncles8
CiliaryGanglion4.45
CingulateCortex8.5
Colorectaladenocarcinoma6.25
DorsalRootGanglion4.65
FetalThyroid6.15
Fetalbrain6.3
Fetalliver5.3
Fetallung4.35
GlobusPallidus5.15
Heart11.7
Hypothalamus6.8
Kidney5.5
Leukemia_chronicMyelogenousK-5627.15
Leukemia_promyelocytic-HL-605.6
Leukemialymphoblastic(MOLT-4)5.15
Liver10.85
Lung6.95
Lymphnode5.5
Lymphoma_burkitts(Daudi)7.85
Lymphoma_burkitts(Raji)8.8
MedullaOblongata5.75
OccipitalLobe5.65
OlfactoryBulb4.9
Ovary4.05
Pancreas4.9
PancreaticIslet6.2
ParietalLobe6.65
Pituitary7.45
Placenta6.25
Pons5.85
PrefrontalCortex7.55
Prostate8.2
Salivarygland5
SkeletalMuscle10.05
Skin4.65
SmoothMuscle6.55
Spinalcord6.65
SubthalamicNucleus5.6
SuperiorCervicalGanglion6.85
TemporalLobe5.75
Testis5.3
TestisGermCell5
TestisIntersitial5.15
TestisLeydigCell6.7
TestisSeminiferousTubule5.4
Thalamus6.35
Thymus4.95
Thyroid7.95
Tongue7.1
Tonsil6.1
Trachea5.2
TrigeminalGanglion6
Uterus5.55
UterusCorpus5.45
WholeBlood6.3
Wholebrain5.5
colon6.2
pineal_day8.34
pineal_night8
retina7.55
small_intestine5.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5663_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.71 ± 0.88
Basal Forebrain1.96 ± 0.36
Basal Part of Pons2.32 ± 0.59
Cerebellar Cortex2.82 ± 0.71
Cerebellar Nuclei2.47 ± 0.77
Claustrum2.77 ± 0.85
Epithalamus2.29 ± 0.58
Frontal Lobe2.64 ± 0.67
Globus Pallidus2.52 ± 0.46
Hypothalamus2.59 ± 1.42
Insula2.36 ± 0.69
Limbic Lobe2.34 ± 0.73
Mesencephalon2.63 ± 0.86
Myelencephalon2.59 ± 0.69
Occipital Lobe2.28 ± 0.78
Parietal Lobe2.51 ± 0.81
Pontine Tegmentum2.48 ± 0.81
Striatum2.26 ± 0.78
Subthalamus2.41 ± 0.61
Temporal Lobe2.58 ± 0.7
Thalamus2.52 ± 0.72
White Matter2.2 ± 0.87
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
NarflCBCerebellum0.06
0.28
NarflCTXCerebral cortex0.87
0.63
NarflHIPHippocampal region3.94
3.44
NarflHPFHippocampal formation3.03
2.49
NarflHYHypothalamus0.53
1.63
NarflLSXLateral septal complex0.05
0
NarflMBMidbrain0.18
0.59
NarflMYMedulla0.18
0.71
NarflOLFOlfactory bulb3.83
3.07
NarflPPons0.91
3.06
NarflPALPallidum0.77
1.71
NarflRHPRetrohippocampal region1.43
1.15
NarflsAMYStriatum-like amygdalar nuclei1.44
1.37
NarflSTRStriatum0.64
0.74
NarflSTRdStriatum dorsal region0.34
0.3
NarflSTRvStriatum ventral region0.99
1.6
NarflTHThalamus0.13
0.13
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00068218 13 313 325 GGGSGGYLEHVFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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