AutismKB 2.0

Annotation Detail for SGK1


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Basic Information Top
Gene Symbol:SGK1 ( SGK )
Gene Full Name: serum/glucocorticoid regulated kinase 1
Band: 6q23.2
Quick LinksEntrez ID:6446; OMIM: 602958; Uniprot ID:SGK1_HUMAN; ENSEMBL ID: ENSG00000118515; HGNC ID: 10810
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus83 / 564012147
neonate29 / 31097932
infant1 / 2362042
juvenile12 / 55556215
adult336 / 1939121173
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor14 / 94178148
cervical tumor12 / 34366349
chondrosarcoma13 / 82823156
colorectal tumor8 / 11424670
esophageal tumor8 / 17290462
gastrointestinal tumor20 / 119369167
germ cell tumor11 / 26384541
glioma14 / 106883130
head and neck tumor50 / 136302366
kidney tumor16 / 68959232
leukemia4 / 9584241
liver tumor18 / 96359186
lung tumor6 / 10312758
lymphoma4 / 7175555
non-neoplasia60 / 97250616
normal983 / 3360307292
ovarian tumor6 / 7668278
pancreatic tumor17 / 104616162
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer10 / 10268097
retinoblastoma2 / 4635643
skin tumor31 / 124949248
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland26 / 33197783
ascites8 / 40015199
bladder13 / 29757436
blood69 / 123478558
bone9 / 71655125
bone marrow1 / 4880120
brain345 / 1100989313
cervix20 / 48171415
connective tissue46 / 149255308
ear2 / 16212123
embryonic tissue5 / 21572223
esophagus8 / 20209395
eye37 / 211054175
heart9 / 89626100
intestine39 / 234472166
kidney63 / 211777297
larynx3 / 24145124
liver29 / 207743139
lung74 / 336974219
lymph2 / 4427045
lymph node4 / 9161043
mammary gland25 / 153271163
mouth43 / 67052641
muscle13 / 107715120
nerve4 / 15768253
ovary12 / 102051117
pancreas21 / 21481297
parathyroid28 / 205391363
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta57 / 280825202
prostate25 / 189345132
salivary gland0 / 201550 
skin63 / 210574299
spleen16 / 53952296
stomach17 / 96619175
testis38 / 330442114
thymus23 / 81131283
thyroid21 / 47473442
tonsil1 / 1699958
trachea16 / 52413305
umbilical cord4 / 13680292
uterus63 / 232878270
vascular127 / 517802452
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201739_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.35
Adipocyte26.25
AdrenalCortex1608.8
Adrenalgland789.5
Amygdala317.45
Appendix28.2
AtrioventricularNode70.25
BDCA4+_DentriticCells905.1
Bonemarrow23.95
BronchialEpithelialCells173.85
CD105+_Endothelial188.35
CD14+_Monocytes2611.6
CD19+_BCells(neg._sel.)25.5
CD33+_Myeloid5658.05
CD34+46.7
CD4+_Tcells20.7
CD56+_NKCells28.65
CD71+_EarlyErythroid21.45
CD8+_Tcells12.05
CardiacMyocytes464.9
Caudatenucleus238.7
Cerebellum47.55
CerebellumPeduncles63.45
CiliaryGanglion61.85
CingulateCortex117.7
Colorectaladenocarcinoma22.15
DorsalRootGanglion72.3
FetalThyroid30.1
Fetalbrain109.55
Fetalliver55.9
Fetallung254.4
GlobusPallidus31
Heart37.15
Hypothalamus369.5
Kidney165.6
Leukemia_chronicMyelogenousK-56263.25
Leukemia_promyelocytic-HL-6074.2
Leukemialymphoblastic(MOLT-4)13.35
Liver32.3
Lung268.35
Lymphnode218.65
Lymphoma_burkitts(Daudi)26.9
Lymphoma_burkitts(Raji)38.4
MedullaOblongata175.55
OccipitalLobe209.85
OlfactoryBulb789.05
Ovary146.6
Pancreas158.35
PancreaticIslet385.9
ParietalLobe213.85
Pituitary32.15
Placenta508.65
Pons61.65
PrefrontalCortex520.45
Prostate248
Salivarygland100.25
SkeletalMuscle21.2
Skin73.65
SmoothMuscle1213.3
Spinalcord304.6
SubthalamicNucleus28.95
SuperiorCervicalGanglion48.65
TemporalLobe28.95
Testis273.3
TestisGermCell225
TestisIntersitial160.45
TestisLeydigCell107.95
TestisSeminiferousTubule109.25
Thalamus225.25
Thymus150
Thyroid448.45
Tongue109.95
Tonsil322.6
Trachea161.7
TrigeminalGanglion29.3
Uterus166.85
UterusCorpus66.05
WholeBlood798.25
Wholebrain228
colon1067.6
pineal_day2136.1
pineal_night1466.72
retina1636.05
small_intestine1515.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14686_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.14 ± 0.46
Basal Forebrain5.67 ± 0.28
Basal Part of Pons6.04 ± 0.34
Cerebellar Cortex5.42 ± 0.26
Cerebellar Nuclei6.29 ± 0.37
Claustrum5.22 ± 0.68
Epithalamus6.12 ± 0.52
Frontal Lobe5.66 ± 0.55
Globus Pallidus6.83 ± 0.29
Hypothalamus5.17 ± 1.12
Insula5.46 ± 0.32
Limbic Lobe5.73 ± 0.64
Mesencephalon5.61 ± 0.53
Myelencephalon5.64 ± 0.65
Occipital Lobe5.48 ± 0.5
Parietal Lobe5.54 ± 0.56
Pontine Tegmentum5.68 ± 0.62
Striatum6.4 ± 0.5
Subthalamus5.97 ± 0.29
Temporal Lobe5.49 ± 0.51
Thalamus5.65 ± 0.5
White Matter8.03 ± 0.42
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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