AutismKB 2.0

Annotation Detail for SCG5


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Basic Information Top
Gene Symbol:SCG5 ( 7B2,P7B2,SGNE1,SgV )
Gene Full Name: secretogranin V (7B2 protein)
Band: 15q13.3
Quick LinksEntrez ID:6447; OMIM: 173120; Uniprot ID:7B2_HUMAN; ENSEMBL ID: ENSG00000166922; HGNC ID: 10816
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult67 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma6 / 10688356
head and neck tumor12 / 13630288
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal437 / 3360307130
ovarian tumor1 / 7668213
pancreatic tumor110 / 1046161051
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain153 / 1100989138
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye10 / 21105447
heart2 / 8962622
intestine4 / 23447217
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle2 / 10771518
nerve1 / 1576863
ovary1 / 1020519
pancreas411 / 2148121913
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland19 / 165851145
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach1 / 9661910
testis8 / 33044224
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203889_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.15
Adipocyte6.4
AdrenalCortex17.3
Adrenalgland9.75
Amygdala807
Appendix7.4
AtrioventricularNode5.55
BDCA4+_DentriticCells6.25
Bonemarrow6.4
BronchialEpithelialCells6.25
CD105+_Endothelial6.05
CD14+_Monocytes6.1
CD19+_BCells(neg._sel.)6.65
CD33+_Myeloid7.5
CD34+7.4
CD4+_Tcells6.2
CD56+_NKCells6.85
CD71+_EarlyErythroid5.6
CD8+_Tcells5.55
CardiacMyocytes8.1
Caudatenucleus609.95
Cerebellum390.25
CerebellumPeduncles355.15
CiliaryGanglion7.3
CingulateCortex514.3
Colorectaladenocarcinoma5.9
DorsalRootGanglion29.15
FetalThyroid103.25
Fetalbrain693.95
Fetalliver6.15
Fetallung5.15
GlobusPallidus286.7
Heart9.65
Hypothalamus1078.1
Kidney5.35
Leukemia_chronicMyelogenousK-5625.5
Leukemia_promyelocytic-HL-605.5
Leukemialymphoblastic(MOLT-4)4.65
Liver8.8
Lung6.6
Lymphnode5.45
Lymphoma_burkitts(Daudi)7.85
Lymphoma_burkitts(Raji)9.05
MedullaOblongata666.3
OccipitalLobe723.25
OlfactoryBulb11.05
Ovary4.35
Pancreas105.45
PancreaticIslet3761.65
ParietalLobe655.05
Pituitary2968.6
Placenta6.2
Pons255.1
PrefrontalCortex893.55
Prostate7.1
Salivarygland5.05
SkeletalMuscle7.55
Skin5.1
SmoothMuscle76.55
Spinalcord232.15
SubthalamicNucleus449.1
SuperiorCervicalGanglion9.55
TemporalLobe454.65
Testis10.05
TestisGermCell7.4
TestisIntersitial5.3
TestisLeydigCell11.1
TestisSeminiferousTubule6.45
Thalamus451.35
Thymus4.85
Thyroid7.85
Tongue6.45
Tonsil6
Trachea5.2
TrigeminalGanglion7.05
Uterus5.45
UterusCorpus6.1
WholeBlood6.35
Wholebrain958.85
colon6.35
pineal_day4125.34
pineal_night3966.32
retina587.675
small_intestine6.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P62081
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.34 ± 0.6
Basal Forebrain11.25 ± 0.56
Basal Part of Pons12.35 ± 0.28
Cerebellar Cortex11.63 ± 0.25
Cerebellar Nuclei11.89 ± 0.38
Claustrum11.89 ± 0.53
Epithalamus10.76 ± 0.79
Frontal Lobe11.92 ± 0.4
Globus Pallidus10.16 ± 0.49
Hypothalamus12.05 ± 0.19
Insula11.99 ± 0.37
Limbic Lobe11.51 ± 0.87
Mesencephalon11.37 ± 0.56
Myelencephalon11.49 ± 0.75
Occipital Lobe11 ± 0.86
Parietal Lobe11.67 ± 0.58
Pontine Tegmentum11.58 ± 0.43
Striatum10.99 ± 0.78
Subthalamus12.25 ± 0.5
Temporal Lobe11.85 ± 0.45
Thalamus11.31 ± 0.41
White Matter10.93 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Scg5CBCerebellum100
100
Scg5CTXCerebral cortex100
100
Scg5HIPHippocampal region100
100
Scg5HPFHippocampal formation100
100
Scg5HYHypothalamus100
100
Scg5LSXLateral septal complex100
100
Scg5MBMidbrain100
100
Scg5MYMedulla100
100
Scg5OLFOlfactory bulb100
100
Scg5PPons100
100
Scg5PALPallidum100
100
Scg5RHPRetrohippocampal region100
100
Scg5sAMYStriatum-like amygdalar nuclei100
100
Scg5STRStriatum100
100
Scg5STRdStriatum dorsal region100
100
Scg5STRvStriatum ventral region100
100
Scg5THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00136365 13 200 212 SVPHFSDEDKDPE Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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