AutismKB 2.0

Annotation Detail for BLVRB


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Basic Information Top
Gene Symbol:BLVRB ( BVRB,FLR,MGC117413,SDR43U1 )
Gene Full Name: biliverdin reductase B (flavin reductase (NADPH))
Band: 19q13.2
Quick LinksEntrez ID:645; OMIM: 600941; Uniprot ID:BLVRB_HUMAN; ENSEMBL ID: ENSG00000090013; HGNC ID: 1063
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus66 / 564012117
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult131 / 193912167
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor25 / 94178265
cervical tumor3 / 3436687
chondrosarcoma9 / 82823108
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor9 / 26384534
glioma16 / 106883149
head and neck tumor12 / 13630288
kidney tumor4 / 6895958
leukemia5 / 9584252
liver tumor4 / 9635941
lung tumor9 / 10312787
lymphoma3 / 7175541
non-neoplasia8 / 9725082
normal165 / 336030749
ovarian tumor5 / 7668265
pancreatic tumor19 / 104616181
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer11 / 102680107
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites4 / 4001599
bladder0 / 297570 
blood5 / 12347840
bone13 / 71655181
bone marrow4 / 4880181
brain47 / 110098942
cervix4 / 4817183
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye7 / 21105433
heart12 / 89626133
intestine15 / 23447263
kidney6 / 21177728
larynx1 / 2414541
liver14 / 20774367
lung27 / 33697480
lymph2 / 4427045
lymph node4 / 9161043
mammary gland27 / 153271176
mouth1 / 6705214
muscle6 / 10771555
nerve1 / 1576863
ovary6 / 10205158
pancreas25 / 214812116
parathyroid7 / 20539340
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate14 / 18934573
salivary gland7 / 20155347
skin7 / 21057433
spleen4 / 5395274
stomach3 / 9661931
testis0 / 3304420 
thymus0 / 811310 
thyroid4 / 4747384
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord2 / 13680146
uterus15 / 23287864
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202201_at
Cell line Expression level Expression bar
721_B_lymphoblasts177.9
Adipocyte70.35
AdrenalCortex23.85
Adrenalgland42.5
Amygdala28.7
Appendix55.95
AtrioventricularNode23.4
BDCA4+_DentriticCells53.75
Bonemarrow753.6
BronchialEpithelialCells435.9
CD105+_Endothelial2946.65
CD14+_Monocytes504.35
CD19+_BCells(neg._sel.)17.65
CD33+_Myeloid323.35
CD34+382.85
CD4+_Tcells8.3
CD56+_NKCells13.55
CD71+_EarlyErythroid5353.85
CD8+_Tcells5.9
CardiacMyocytes44.8
Caudatenucleus21.1
Cerebellum19.2
CerebellumPeduncles43
CiliaryGanglion28.85
CingulateCortex23.4
Colorectaladenocarcinoma41.25
DorsalRootGanglion23.85
FetalThyroid104.7
Fetalbrain20.5
Fetalliver1034.2
Fetallung387.4
GlobusPallidus13.75
Heart552.2
Hypothalamus37.75
Kidney94.9
Leukemia_chronicMyelogenousK-562402.9
Leukemia_promyelocytic-HL-6058.4
Leukemialymphoblastic(MOLT-4)16.8
Liver1121.1
Lung427.05
Lymphnode41.75
Lymphoma_burkitts(Daudi)64.65
Lymphoma_burkitts(Raji)137.7
MedullaOblongata20.95
OccipitalLobe19.55
OlfactoryBulb32.7
Ovary30.65
Pancreas33.55
PancreaticIslet50.5
ParietalLobe36.65
Pituitary18.4
Placenta86.45
Pons26.45
PrefrontalCortex23.7
Prostate275.3
Salivarygland33.8
SkeletalMuscle104.65
Skin28.85
SmoothMuscle52.3
Spinalcord52.9
SubthalamicNucleus14.55
SuperiorCervicalGanglion16.5
TemporalLobe40.45
Testis19.9
TestisGermCell12.05
TestisIntersitial7.1
TestisLeydigCell14.4
TestisSeminiferousTubule14.9
Thalamus40.85
Thymus41.25
Thyroid108.8
Tongue101.55
Tonsil42.1
Trachea33
TrigeminalGanglion28.8
Uterus37.55
UterusCorpus37.25
WholeBlood99.8
Wholebrain53.1
colon71.45
pineal_day34.52
pineal_night39.88
retina52
small_intestine75.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P153351
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.13 ± 0.37
Basal Forebrain9.07 ± 0.18
Basal Part of Pons9.42 ± 0.27
Cerebellar Cortex8.68 ± 0.26
Cerebellar Nuclei9.21 ± 0.56
Claustrum8.89 ± 0.32
Epithalamus8.81 ± 0.33
Frontal Lobe9.08 ± 0.33
Globus Pallidus9.43 ± 0.16
Hypothalamus9.06 ± 0.26
Insula9.17 ± 0.33
Limbic Lobe9.08 ± 0.43
Mesencephalon8.97 ± 0.4
Myelencephalon9.09 ± 0.39
Occipital Lobe8.62 ± 0.3
Parietal Lobe8.88 ± 0.32
Pontine Tegmentum8.86 ± 0.27
Striatum9.04 ± 0.35
Subthalamus8.9 ± 0.29
Temporal Lobe9.14 ± 0.39
Thalamus9.05 ± 0.36
White Matter8.79 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
BlvrbCBCerebellum2.81
4.64
BlvrbCTXCerebral cortex9.22
8.16
BlvrbHIPHippocampal region2.41
2.54
BlvrbHPFHippocampal formation1.69
1.8
BlvrbHYHypothalamus1.92
1.53
BlvrbLSXLateral septal complex0.82
0.52
BlvrbMBMidbrain1.15
1.63
BlvrbMYMedulla1.25
1.67
BlvrbOLFOlfactory bulb6.84
6.85
BlvrbPPons0.82
1.13
BlvrbPALPallidum0.53
0.54
BlvrbRHPRetrohippocampal region0.71
0.95
BlvrbsAMYStriatum-like amygdalar nuclei1.01
0.74
BlvrbSTRStriatum1.05
1.07
BlvrbSTRdStriatum dorsal region0.71
0.93
BlvrbSTRvStriatum ventral region2.26
1.8
BlvrbTHThalamus4.25
4.88
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
BLVRB_HUMAN_0 0 0 0 DSSRLPSEGPRPAHVVVGDVLQAADVDK PRIDE
BLVRB_HUMAN_0 0 0 0 LQAVTDDHIR PRIDE
BLVRB_HUMAN_0 0 0 0 TVAGQDAVIVLLGTR PRIDE
BLVRB_HUMAN_105 19 105 123 VVACTSAFLLWDPTKVPPR PRIDE
BLVRB_HUMAN_124 10 124 133 LQAVTDDHIR PRIDE
BLVRB_HUMAN_145 25 145 169 YVAVMPPHIGDQPLTGAYTVTLDGR PRIDE
BLVRB_HUMAN_174 13 174 186 VISKHDLGHFMLR PRIDE
BLVRB_HUMAN_187 19 187 205 CLTTDEYDGHSTYPSHQYQ PRIDE
BLVRB_HUMAN_35 28 35 62 DSSRLPSEGPRPAHVVVGDVLQAADVDK PRIDE
BLVRB_HUMAN_39 24 39 62 LPSEGPRPAHVVVGDVLQAADVDK PRIDE
BLVRB_HUMAN_39 39 39 77 LPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTR PRIDE
BLVRB_HUMAN_46 32 46 77 PAHVVVGDVLQAADVDKTVAGQDAVIVLLGTR PRIDE
BLVRB_HUMAN_63 15 63 77 TVAGQDAVIVLLGTR PRIDE
BLVRB_HUMAN_78 14 78 91 NDLSPTTVMSEGAR PRIDE
PAp00001190 19 188 206 CLTTDEYDGHSTYPSHQYQ Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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