Annotation Detail for SH3BP2
Basic Information Top
| Gene Symbol: | SH3BP2 ( 3BP2,CRBM,CRPM,FLJ42079,FLJ54978 ) |
|---|---|
| Gene Full Name: | SH3-domain binding protein 2 |
| Band: | 4p16.3 |
| Quick Links | Entrez ID:6452; OMIM: 602104; Uniprot ID:3BP2_HUMAN; ENSEMBL ID: ENSG00000087266; HGNC ID: 10825 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.167679
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 5 / 62319 | 80 |  |
| fetus | 21 / 564012 | 37 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 107 / 1939121 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 11 / 94178 | 116 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 7 / 114246 | 61 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 |  |
| germ cell tumor | 6 / 263845 | 22 | |
| glioma | 12 / 106883 | 112 | |
| head and neck tumor | 10 / 136302 | 73 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 12 / 95842 | 125 | |
| liver tumor | 6 / 96359 | 62 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 6 / 97250 | 61 | |
| normal | 170 / 3360307 | 50 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 3 / 29757 | 100 | |
| blood | 19 / 123478 | 153 | |
| bone | 6 / 71655 | 83 | |
| bone marrow | 10 / 48801 | 204 |  |
| brain | 43 / 1100989 | 39 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 7 / 149255 | 46 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 8 / 211054 | 37 | |
| heart | 1 / 89626 | 11 | |
| intestine | 11 / 234472 | 46 | |
| kidney | 19 / 211777 | 89 | |
| larynx | 1 / 24145 | 41 | |
| liver | 8 / 207743 | 38 | |
| lung | 28 / 336974 | 83 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 15 / 153271 | 97 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 3 / 15768 | 190 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 15 / 280825 | 53 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 7 / 210574 | 33 | |
| spleen | 16 / 53952 | 296 | |
| stomach | 2 / 96619 | 20 | |
| testis | 7 / 330442 | 21 | |
| thymus | 5 / 81131 | 61 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 2 / 16999 | 117 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 10 / 232878 | 42 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 211250_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6.8 | |
| Adipocyte | 5.05 | |
| AdrenalCortex | 5.45 | |
| Adrenalgland | 4.4 | |
| Amygdala | 5.25 | |
| Appendix | 5.45 | |
| AtrioventricularNode | 4.1 | |
| BDCA4+_DentriticCells | 6.95 | |
| Bonemarrow | 5.2 | |
| BronchialEpithelialCells | 5 | |
| CD105+_Endothelial | 5.05 | |
| CD14+_Monocytes | 56.3 | |
| CD19+_BCells(neg._sel.) | 14 | |
| CD33+_Myeloid | 7.25 | |
| CD34+ | 6.2 | |
| CD4+_Tcells | 7.2 | |
| CD56+_NKCells | 10.05 | |
| CD71+_EarlyErythroid | 4.95 | |
| CD8+_Tcells | 4.9 | |
| CardiacMyocytes | 6.6 | |
| Caudatenucleus | 4.65 | |
| Cerebellum | 4.15 | |
| CerebellumPeduncles | 5.95 | |
| CiliaryGanglion | 3.8 | |
| CingulateCortex | 5.3 | |
| Colorectaladenocarcinoma | 5.45 | |
| DorsalRootGanglion | 4.05 | |
| FetalThyroid | 5 | |
| Fetalbrain | 5.35 | |
| Fetalliver | 4.45 | |
| Fetallung | 4.35 | |
| GlobusPallidus | 3.8 | |
| Heart | 6.9 | |
| Hypothalamus | 5.5 | |
| Kidney | 4.35 | |
| Leukemia_chronicMyelogenousK-562 | 4.6 | |
| Leukemia_promyelocytic-HL-60 | 4.55 | |
| Leukemialymphoblastic(MOLT-4) | 4.15 | |
| Liver | 7.1 | |
| Lung | 10.4 | |
| Lymphnode | 5.15 | |
| Lymphoma_burkitts(Daudi) | 6.7 | |
| Lymphoma_burkitts(Raji) | 7.4 | |
| MedullaOblongata | 4.65 | |
| OccipitalLobe | 4.55 | |
| OlfactoryBulb | 4.05 | |
| Ovary | 3.55 | |
| Pancreas | 4.15 | |
| PancreaticIslet | 5.45 | |
| ParietalLobe | 5.55 | |
| Pituitary | 5.95 | |
| Placenta | 10.45 | |
| Pons | 4.95 | |
| PrefrontalCortex | 6.25 | |
| Prostate | 5.95 | |
| Salivarygland | 4.15 | |
| SkeletalMuscle | 6.3 | |
| Skin | 4 | |
| SmoothMuscle | 5.85 | |
| Spinalcord | 5.5 | |
| SubthalamicNucleus | 4.85 | |
| SuperiorCervicalGanglion | 6.35 | |
| TemporalLobe | 4.75 | |
| Testis | 4.4 | |
| TestisGermCell | 4.15 | |
| TestisIntersitial | 4.3 | |
| TestisLeydigCell | 5.1 | |
| TestisSeminiferousTubule | 4.4 | |
| Thalamus | 5.25 | |
| Thymus | 4.15 | |
| Thyroid | 6.3 | |
| Tongue | 5.2 | |
| Tonsil | 5 | |
| Trachea | 4.3 | |
| TrigeminalGanglion | 5.45 | |
| Uterus | 4.6 | |
| UterusCorpus | 5 | |
| WholeBlood | 34.55 | |
| Wholebrain | 4.3 | |
| colon | 5.2 | |
| pineal_day | 6.3 | |
| pineal_night | 6.14 | |
| retina | 6.175 | |
| small_intestine | 4.9 | |
- Probe name: A_23_P110116
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.9 ± 0.74 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.01 ± 0.71 | |
| Basal Part of Pons | 2.53 ± 0.5 | |
| Cerebellar Cortex | 2.83 ± 0.6 | |
| Cerebellar Nuclei | 3.51 ± 0.61 | |
| Claustrum | 3.08 ± 0.56 | |
| Epithalamus | 3.41 ± 0.53 | |
| Frontal Lobe | 3.02 ± 0.69 | |
| Globus Pallidus | 4.44 ± 0.36 | |
| Hypothalamus | 3.13 ± 0.36 | |
| Insula | 2.79 ± 0.58 | |
| Limbic Lobe | 2.74 ± 0.76 | |
| Mesencephalon | 3.26 ± 0.79 | |
| Myelencephalon | 3.26 ± 0.74 | |
| Occipital Lobe | 3.34 ± 0.79 | |
| Parietal Lobe | 3.17 ± 0.8 | |
| Pontine Tegmentum | 3.19 ± 0.63 | |
| Striatum | 3.77 ± 0.65 | |
| Subthalamus | 3.09 ± 0.95 | |
| Temporal Lobe | 2.97 ± 0.64 | |
| Thalamus | 3.59 ± 0.59 | |
| White Matter | 2.71 ± 0.7 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Sh3bp2 | CB | Cerebellum | 0.93 | |
| 2.12 | | |||
| Sh3bp2 | CTX | Cerebral cortex | 3.27 | |
| 2.9 | | |||
| Sh3bp2 | HIP | Hippocampal region | 3.39 | |
| 3.36 | | |||
| Sh3bp2 | HPF | Hippocampal formation | 2.23 | |
| 2.45 | | |||
| Sh3bp2 | HY | Hypothalamus | 0.13 | |
| 0.21 | | |||
| Sh3bp2 | LSX | Lateral septal complex | 0.43 | |
| 0.6 | | |||
| Sh3bp2 | MB | Midbrain | 0.83 | |
| 1.98 | | |||
| Sh3bp2 | MY | Medulla | 0.09 | |
| 0.24 | | |||
| Sh3bp2 | OLF | Olfactory bulb | 2.04 | |
| 3.31 | | |||
| Sh3bp2 | P | Pons | 0.26 | |
| 0.79 | | |||
| Sh3bp2 | PAL | Pallidum | 0.12 | |
| 0.1 | | |||
| Sh3bp2 | RHP | Retrohippocampal region | 0.75 | |
| 1.44 | | |||
| Sh3bp2 | sAMY | Striatum-like amygdalar nuclei | 0.19 | |
| 0.56 | | |||
| Sh3bp2 | STR | Striatum | 0.34 | |
| 0.82 | | |||
| Sh3bp2 | STRd | Striatum dorsal region | 0.43 | |
| 1.11 | | |||
| Sh3bp2 | STRv | Striatum ventral region | 0.14 | |
| 0.21 | | |||
| Sh3bp2 | TH | Thalamus | 0.41 | |
| 0.57 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| 3BP2_HUMAN_214 | 9 | 214 | 222 | KPAFSDMPR | PRIDE |