AutismKB 2.0

Annotation Detail for C16orf58


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Basic Information Top
Gene Symbol:C16orf58 ( FLJ13868 )
Gene Full Name: chromosome 16 open reading frame 58
Band: 16p11.2
Quick LinksEntrez ID:64755; OMIM: NA; Uniprot ID:CP058_HUMAN; ENSEMBL ID: ENSG00000140688; HGNC ID: 25848
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus74 / 564012131
neonate4 / 31097128
infant2 / 2362084
juvenile7 / 55556125
adult177 / 193912191
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222190_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts63.8
Adipocyte18.9
AdrenalCortex20.5
Adrenalgland16.85
Amygdala20.7
Appendix19.35
AtrioventricularNode14.7
BDCA4+_DentriticCells29.1
Bonemarrow18.95
BronchialEpithelialCells19.2
CD105+_Endothelial23.5
CD14+_Monocytes20.95
CD19+_BCells(neg._sel.)39.05
CD33+_Myeloid25.35
CD34+47.4
CD4+_Tcells34.35
CD56+_NKCells23.85
CD71+_EarlyErythroid24.95
CD8+_Tcells29.3
CardiacMyocytes21.35
Caudatenucleus17.25
Cerebellum15.75
CerebellumPeduncles22.05
CiliaryGanglion13.85
CingulateCortex20.5
Colorectaladenocarcinoma19.65
DorsalRootGanglion14.8
FetalThyroid24.9
Fetalbrain19.25
Fetalliver16.7
Fetallung16.05
GlobusPallidus17.6
Heart24.2
Hypothalamus21.1
Kidney16.5
Leukemia_chronicMyelogenousK-56217.85
Leukemia_promyelocytic-HL-6016.05
Leukemialymphoblastic(MOLT-4)14.8
Liver37.8
Lung21.05
Lymphnode18.6
Lymphoma_burkitts(Daudi)24.2
Lymphoma_burkitts(Raji)27.75
MedullaOblongata17.4
OccipitalLobe17.65
OlfactoryBulb15.15
Ovary12.95
Pancreas16.65
PancreaticIslet30.65
ParietalLobe21.15
Pituitary23.05
Placenta20.6
Pons18.65
PrefrontalCortex24.45
Prostate27.4
Salivarygland15.15
SkeletalMuscle22.55
Skin14.9
SmoothMuscle21.45
Spinalcord20.5
SubthalamicNucleus17.8
SuperiorCervicalGanglion21.95
TemporalLobe17.65
Testis16.85
TestisGermCell16.6
TestisIntersitial16.3
TestisLeydigCell19.2
TestisSeminiferousTubule16.65
Thalamus19.7
Thymus15.75
Thyroid27.75
Tongue19
Tonsil18.85
Trachea16.6
TrigeminalGanglion19.4
Uterus15.8
UterusCorpus17.75
WholeBlood20.1
Wholebrain17.85
colon16.65
pineal_day26.08
pineal_night24.12
retina23.3
small_intestine18.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P65271
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.32 ± 0.3
Basal Forebrain5.96 ± 0.32
Basal Part of Pons5.86 ± 0.37
Cerebellar Cortex6.13 ± 0.34
Cerebellar Nuclei5.59 ± 0.37
Claustrum6.31 ± 0.62
Epithalamus5.67 ± 0.27
Frontal Lobe5.84 ± 0.37
Globus Pallidus5.93 ± 0.34
Hypothalamus5.76 ± 0.3
Insula5.95 ± 0.26
Limbic Lobe6.25 ± 0.43
Mesencephalon6.03 ± 0.45
Myelencephalon6 ± 0.42
Occipital Lobe6.26 ± 0.44
Parietal Lobe5.94 ± 0.44
Pontine Tegmentum5.9 ± 0.42
Striatum6.07 ± 0.41
Subthalamus5.78 ± 0.57
Temporal Lobe5.99 ± 0.32
Thalamus5.86 ± 0.34
White Matter6.62 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
BC017158CBCerebellum28.5
35.09
BC017158CTXCerebral cortex17.7
12.19
BC017158HIPHippocampal region18.71
17.41
BC017158HPFHippocampal formation19.11
17.02
BC017158HYHypothalamus10.14
7.47
BC017158LSXLateral septal complex9.26
5.96
BC017158MBMidbrain16.72
14.63
BC017158MYMedulla32.16
35.27
BC017158OLFOlfactory bulb27.57
20.97
BC017158PPons16.8
17.3
BC017158PALPallidum8.35
6.61
BC017158RHPRetrohippocampal region19.36
16.16
BC017158sAMYStriatum-like amygdalar nuclei7.21
4.77
BC017158STRStriatum5.85
4.6
BC017158STRdStriatum dorsal region4.23
3.98
BC017158STRvStriatum ventral region8.25
4.95
BC017158THThalamus13.56
11.03
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00028919 25 381 405 AATHGLMLGALQGDGPLPAELEELR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018