AutismKB 2.0

Annotation Detail for C16orf58


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Basic Information Top
Gene Symbol:C16orf58 ( FLJ13868 )
Gene Full Name: chromosome 16 open reading frame 58
Band: 16p11.2
Quick LinksEntrez ID:64755; OMIM: NA; Uniprot ID:CP058_HUMAN; ENSEMBL ID: ENSG00000140688; HGNC ID: 25848
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus74 / 564012131
neonate4 / 31097128
infant2 / 2362084
juvenile7 / 55556125
adult177 / 193912191
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor10 / 94178106
cervical tumor3 / 3436687
chondrosarcoma13 / 82823156
colorectal tumor16 / 114246140
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor52 / 263845197
glioma11 / 106883102
head and neck tumor34 / 136302249
kidney tumor8 / 68959116
leukemia5 / 9584252
liver tumor13 / 96359134
lung tumor7 / 10312767
lymphoma8 / 71755111
non-neoplasia13 / 97250133
normal373 / 3360307111
ovarian tumor10 / 76682130
pancreatic tumor20 / 104616191
primitive neuroectodermal tumor of the CNS27 / 125680214
prostate cancer3 / 10268029
retinoblastoma4 / 4635686
skin tumor16 / 124949128
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor17 / 90257188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites1 / 4001524
bladder2 / 2975767
blood8 / 12347864
bone5 / 7165569
bone marrow0 / 488010 
brain182 / 1100989165
cervix7 / 48171145
connective tissue25 / 149255167
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye18 / 21105485
heart4 / 8962644
intestine34 / 234472145
kidney28 / 211777132
larynx1 / 2414541
liver18 / 20774386
lung28 / 33697483
lymph2 / 4427045
lymph node1 / 9161010
mammary gland12 / 15327178
mouth30 / 67052447
muscle8 / 10771574
nerve0 / 157680 
ovary14 / 102051137
pancreas24 / 214812111
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta26 / 28082592
prostate38 / 189345200
salivary gland1 / 2015549
skin24 / 210574113
spleen8 / 53952148
stomach5 / 9661951
testis60 / 330442181
thymus24 / 81131295
thyroid10 / 47473210
tonsil1 / 1699958
trachea14 / 52413267
umbilical cord1 / 1368073
uterus28 / 232878120
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222190_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts63.8
Adipocyte18.9
AdrenalCortex20.5
Adrenalgland16.85
Amygdala20.7
Appendix19.35
AtrioventricularNode14.7
BDCA4+_DentriticCells29.1
Bonemarrow18.95
BronchialEpithelialCells19.2
CD105+_Endothelial23.5
CD14+_Monocytes20.95
CD19+_BCells(neg._sel.)39.05
CD33+_Myeloid25.35
CD34+47.4
CD4+_Tcells34.35
CD56+_NKCells23.85
CD71+_EarlyErythroid24.95
CD8+_Tcells29.3
CardiacMyocytes21.35
Caudatenucleus17.25
Cerebellum15.75
CerebellumPeduncles22.05
CiliaryGanglion13.85
CingulateCortex20.5
Colorectaladenocarcinoma19.65
DorsalRootGanglion14.8
FetalThyroid24.9
Fetalbrain19.25
Fetalliver16.7
Fetallung16.05
GlobusPallidus17.6
Heart24.2
Hypothalamus21.1
Kidney16.5
Leukemia_chronicMyelogenousK-56217.85
Leukemia_promyelocytic-HL-6016.05
Leukemialymphoblastic(MOLT-4)14.8
Liver37.8
Lung21.05
Lymphnode18.6
Lymphoma_burkitts(Daudi)24.2
Lymphoma_burkitts(Raji)27.75
MedullaOblongata17.4
OccipitalLobe17.65
OlfactoryBulb15.15
Ovary12.95
Pancreas16.65
PancreaticIslet30.65
ParietalLobe21.15
Pituitary23.05
Placenta20.6
Pons18.65
PrefrontalCortex24.45
Prostate27.4
Salivarygland15.15
SkeletalMuscle22.55
Skin14.9
SmoothMuscle21.45
Spinalcord20.5
SubthalamicNucleus17.8
SuperiorCervicalGanglion21.95
TemporalLobe17.65
Testis16.85
TestisGermCell16.6
TestisIntersitial16.3
TestisLeydigCell19.2
TestisSeminiferousTubule16.65
Thalamus19.7
Thymus15.75
Thyroid27.75
Tongue19
Tonsil18.85
Trachea16.6
TrigeminalGanglion19.4
Uterus15.8
UterusCorpus17.75
WholeBlood20.1
Wholebrain17.85
colon16.65
pineal_day26.08
pineal_night24.12
retina23.3
small_intestine18.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P65271
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.32 ± 0.3
Basal Forebrain5.96 ± 0.32
Basal Part of Pons5.86 ± 0.37
Cerebellar Cortex6.13 ± 0.34
Cerebellar Nuclei5.59 ± 0.37
Claustrum6.31 ± 0.62
Epithalamus5.67 ± 0.27
Frontal Lobe5.84 ± 0.37
Globus Pallidus5.93 ± 0.34
Hypothalamus5.76 ± 0.3
Insula5.95 ± 0.26
Limbic Lobe6.25 ± 0.43
Mesencephalon6.03 ± 0.45
Myelencephalon6 ± 0.42
Occipital Lobe6.26 ± 0.44
Parietal Lobe5.94 ± 0.44
Pontine Tegmentum5.9 ± 0.42
Striatum6.07 ± 0.41
Subthalamus5.78 ± 0.57
Temporal Lobe5.99 ± 0.32
Thalamus5.86 ± 0.34
White Matter6.62 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
BC017158CBCerebellum28.5
35.09
BC017158CTXCerebral cortex17.7
12.19
BC017158HIPHippocampal region18.71
17.41
BC017158HPFHippocampal formation19.11
17.02
BC017158HYHypothalamus10.14
7.47
BC017158LSXLateral septal complex9.26
5.96
BC017158MBMidbrain16.72
14.63
BC017158MYMedulla32.16
35.27
BC017158OLFOlfactory bulb27.57
20.97
BC017158PPons16.8
17.3
BC017158PALPallidum8.35
6.61
BC017158RHPRetrohippocampal region19.36
16.16
BC017158sAMYStriatum-like amygdalar nuclei7.21
4.77
BC017158STRStriatum5.85
4.6
BC017158STRdStriatum dorsal region4.23
3.98
BC017158STRvStriatum ventral region8.25
4.95
BC017158THThalamus13.56
11.03
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00028919 25 381 405 AATHGLMLGALQGDGPLPAELEELR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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