AutismKB 2.0

Annotation Detail for MOSC1


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Basic Information Top
Gene Symbol:MOSC1 ( FLJ22390,MARC1 )
Gene Full Name: MOCO sulphurase C-terminal domain containing 1
Band: 1q41
Quick LinksEntrez ID:64757; OMIM: NA; Uniprot ID:MOSC1_HUMAN; ENSEMBL ID: ENSG00000186205; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor8 / 34366232
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor7 / 26384526
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal84 / 336030724
ovarian tumor1 / 7668213
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer11 / 102680107
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone2 / 7165527
bone marrow0 / 488010 
brain10 / 11009899
cervix8 / 48171166
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine5 / 23447221
kidney7 / 21177733
larynx0 / 241450 
liver4 / 20774319
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas5 / 21481223
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta15 / 28082553
prostate21 / 189345110
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach2 / 9661920
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218865_at
Cell line Expression level Expression bar
721_B_lymphoblasts33.65
Adipocyte576.6
AdrenalCortex120.5
Adrenalgland83.3
Amygdala97.8
Appendix167.25
AtrioventricularNode135.05
BDCA4+_DentriticCells31.35
Bonemarrow210.5
BronchialEpithelialCells58
CD105+_Endothelial25.3
CD14+_Monocytes174.05
CD19+_BCells(neg._sel.)27.15
CD33+_Myeloid251.1
CD34+55.1
CD4+_Tcells21.05
CD56+_NKCells18.55
CD71+_EarlyErythroid47.4
CD8+_Tcells19.3
CardiacMyocytes142.9
Caudatenucleus147.65
Cerebellum139.6
CerebellumPeduncles112
CiliaryGanglion88.55
CingulateCortex140.4
Colorectaladenocarcinoma54.7
DorsalRootGanglion136.05
FetalThyroid112.65
Fetalbrain128.2
Fetalliver165.75
Fetallung85.55
GlobusPallidus71.3
Heart118.55
Hypothalamus110.15
Kidney121.25
Leukemia_chronicMyelogenousK-56289.5
Leukemia_promyelocytic-HL-6078.55
Leukemialymphoblastic(MOLT-4)80.3
Liver188.2
Lung107.7
Lymphnode82.75
Lymphoma_burkitts(Daudi)113.65
Lymphoma_burkitts(Raji)115.9
MedullaOblongata79.25
OccipitalLobe89.3
OlfactoryBulb96.75
Ovary88.1
Pancreas79.6
PancreaticIslet96.7
ParietalLobe148.25
Pituitary172.9
Placenta201.9
Pons111.15
PrefrontalCortex96.05
Prostate125.15
Salivarygland88.45
SkeletalMuscle102.65
Skin127.95
SmoothMuscle62.65
Spinalcord115.55
SubthalamicNucleus100.85
SuperiorCervicalGanglion189.2
TemporalLobe88.95
Testis86.35
TestisGermCell55
TestisIntersitial82.75
TestisLeydigCell79.35
TestisSeminiferousTubule85
Thalamus101.7
Thymus78.25
Thyroid257.45
Tongue100.5
Tonsil92.7
Trachea108.15
TrigeminalGanglion146.4
Uterus54.55
UterusCorpus105.65
WholeBlood154.4
Wholebrain86.4
colon132
pineal_day88.74
pineal_night82.66
retina98.75
small_intestine96.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11895_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.24 ± 0.52
Basal Forebrain5.42 ± 0.28
Basal Part of Pons4.94 ± 0.32
Cerebellar Cortex5.23 ± 0.29
Cerebellar Nuclei4.98 ± 0.48
Claustrum5.49 ± 0.54
Epithalamus5.23 ± 0.45
Frontal Lobe5.17 ± 0.37
Globus Pallidus5.7 ± 0.41
Hypothalamus5.37 ± 0.37
Insula5.24 ± 0.38
Limbic Lobe5.28 ± 0.38
Mesencephalon5.29 ± 0.53
Myelencephalon5.28 ± 0.44
Occipital Lobe5.34 ± 0.36
Parietal Lobe5.21 ± 0.43
Pontine Tegmentum5.35 ± 0.47
Striatum5.52 ± 0.47
Subthalamus4.96 ± 0.65
Temporal Lobe5.18 ± 0.38
Thalamus5.24 ± 0.44
White Matter3.88 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mosc1CBCerebellum0.22
0.46
Mosc1CTXCerebral cortex0.62
1.02
Mosc1HIPHippocampal region0.59
0.71
Mosc1HPFHippocampal formation0.46
0.5
Mosc1HYHypothalamus0.13
0.11
Mosc1LSXLateral septal complex0.41
0.52
Mosc1MBMidbrain0.3
0.78
Mosc1MYMedulla0.19
0.57
Mosc1OLFOlfactory bulb0.75
1.07
Mosc1PPons0.34
0.6
Mosc1PALPallidum0.19
0.23
Mosc1RHPRetrohippocampal region0.25
0.21
Mosc1sAMYStriatum-like amygdalar nuclei0.47
1.28
Mosc1STRStriatum0.16
0.24
Mosc1STRdStriatum dorsal region0.12
0.12
Mosc1STRvStriatum ventral region0.08
0.12
Mosc1THThalamus0.17
0.21
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003173 15 71 85 GVPVSEAECTAMGLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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