AutismKB 2.0

Annotation Detail for FAM59A


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Basic Information Top
Gene Symbol:FAM59A ( C18orf11,GAREM,Gm944 )
Gene Full Name: family with sequence similarity 59, member A
Band: 18q12.1
Quick LinksEntrez ID:64762; OMIM: NA; Uniprot ID:FA59A_HUMAN; ENSEMBL ID: ENSG00000141441; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult20 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor7 / 10312767
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal41 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites4 / 4001599
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain12 / 110098910
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye4 / 21105418
heart1 / 8962611
intestine3 / 23447212
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219377_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.05
Adipocyte6
AdrenalCortex6.45
Adrenalgland5.55
Amygdala7.75
Appendix6
AtrioventricularNode4.7
BDCA4+_DentriticCells6.55
Bonemarrow5.95
BronchialEpithelialCells5.8
CD105+_Endothelial5.85
CD14+_Monocytes6.15
CD19+_BCells(neg._sel.)6.15
CD33+_Myeloid6.9
CD34+7.3
CD4+_Tcells6.25
CD56+_NKCells6.9
CD71+_EarlyErythroid5.55
CD8+_Tcells5.25
CardiacMyocytes7.8
Caudatenucleus5.3
Cerebellum8.5
CerebellumPeduncles10.2
CiliaryGanglion4.5
CingulateCortex8.3
Colorectaladenocarcinoma5.95
DorsalRootGanglion4.65
FetalThyroid5.75
Fetalbrain6.05
Fetalliver5.15
Fetallung5.1
GlobusPallidus4.4
Heart7.55
Hypothalamus7.6
Kidney6.8
Leukemia_chronicMyelogenousK-5625.4
Leukemia_promyelocytic-HL-605.3
Leukemialymphoblastic(MOLT-4)4.65
Liver8.3
Lung6.7
Lymphnode4.7
Lymphoma_burkitts(Daudi)7.75
Lymphoma_burkitts(Raji)8.35
MedullaOblongata5.7
OccipitalLobe11.45
OlfactoryBulb5.6
Ovary3.95
Pancreas7.35
PancreaticIslet8.6
ParietalLobe10.45
Pituitary7
Placenta6.15
Pons5.65
PrefrontalCortex26.35
Prostate15.3
Salivarygland4.8
SkeletalMuscle7.65
Skin4.6
SmoothMuscle7.5
Spinalcord6.45
SubthalamicNucleus5.45
SuperiorCervicalGanglion7.25
TemporalLobe5.45
Testis5.15
TestisGermCell5.25
TestisIntersitial5.05
TestisLeydigCell5.95
TestisSeminiferousTubule5.2
Thalamus6.1
Thymus4.35
Thyroid7.25
Tongue5.8
Tonsil5.85
Trachea6.3
TrigeminalGanglion6.95
Uterus5.85
UterusCorpus5.45
WholeBlood6.25
Wholebrain15.65
colon9.3
pineal_day7.36
pineal_night7.3
retina23.2
small_intestine15.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P370042
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.69 ± 0.48
Basal Forebrain6.83 ± 0.25
Basal Part of Pons7.31 ± 0.21
Cerebellar Cortex7.53 ± 0.2
Cerebellar Nuclei7.25 ± 0.24
Claustrum6.48 ± 0.49
Epithalamus7.56 ± 0.46
Frontal Lobe7.3 ± 0.35
Globus Pallidus7.18 ± 0.27
Hypothalamus7.13 ± 0.28
Insula7.39 ± 0.4
Limbic Lobe7.29 ± 0.44
Mesencephalon7.13 ± 0.37
Myelencephalon7.2 ± 0.36
Occipital Lobe7.22 ± 0.3
Parietal Lobe7.17 ± 0.36
Pontine Tegmentum7.09 ± 0.33
Striatum6.94 ± 0.42
Subthalamus7 ± 0.11
Temporal Lobe7.13 ± 0.34
Thalamus7.14 ± 0.29
White Matter8.32 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gm944CBCerebellum61.73
93.66
Gm944CTXCerebral cortex60.71
49.13
Gm944HIPHippocampal region60.12
93.12
Gm944HPFHippocampal formation53.63
69.4
Gm944HYHypothalamus39.39
31.87
Gm944LSXLateral septal complex100
84.17
Gm944MBMidbrain36.21
33.09
Gm944MYMedulla34.6
36.36
Gm944OLFOlfactory bulb87.84
100
Gm944PPons33.95
34.48
Gm944PALPallidum42.08
37.13
Gm944RHPRetrohippocampal region41.61
35.24
Gm944sAMYStriatum-like amygdalar nuclei37.14
27.98
Gm944STRStriatum63.45
49.97
Gm944STRdStriatum dorsal region60
47.39
Gm944STRvStriatum ventral region76.24
61.23
Gm944THThalamus48.39
42.86
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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