AutismKB 2.0

Annotation Detail for ZNF574


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Basic Information Top
Gene Symbol:ZNF574 ( FLJ22059,FP972 )
Gene Full Name: zinc finger protein 574
Band: 19q13.2
Quick LinksEntrez ID:64763; OMIM: NA; Uniprot ID:ZN574_HUMAN; ENSEMBL ID: ENSG00000105732; HGNC ID: 26166
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst4 / 6231964
fetus27 / 56401247
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor19 / 26384572
glioma5 / 10688346
head and neck tumor4 / 13630229
kidney tumor4 / 6895958
leukemia9 / 9584293
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma17 / 71755236
non-neoplasia1 / 9725010
normal140 / 336030741
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer4 / 10268038
retinoblastoma5 / 46356107
skin tumor16 / 124949128
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder2 / 2975767
blood5 / 12347840
bone1 / 7165513
bone marrow1 / 4880120
brain57 / 110098951
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye15 / 21105471
heart1 / 8962611
intestine8 / 23447234
kidney6 / 21177728
larynx4 / 24145165
liver1 / 2077434
lung7 / 33697420
lymph13 / 44270293
lymph node3 / 9161032
mammary gland5 / 15327132
mouth1 / 6705214
muscle11 / 107715102
nerve1 / 1576863
ovary4 / 10205139
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate8 / 18934542
salivary gland0 / 201550 
skin18 / 21057485
spleen3 / 5395255
stomach2 / 9661920
testis50 / 330442151
thymus7 / 8113186
thyroid0 / 474730 
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218762_at
Cell line Expression level Expression bar
721_B_lymphoblasts48.55
Adipocyte38.2
AdrenalCortex37.45
Adrenalgland53.35
Amygdala35.6
Appendix35.2
AtrioventricularNode32.45
BDCA4+_DentriticCells39.5
Bonemarrow36.45
BronchialEpithelialCells24
CD105+_Endothelial41.4
CD14+_Monocytes33.9
CD19+_BCells(neg._sel.)31.6
CD33+_Myeloid33.4
CD34+100.05
CD4+_Tcells27.65
CD56+_NKCells42.05
CD71+_EarlyErythroid44.9
CD8+_Tcells15.05
CardiacMyocytes28.45
Caudatenucleus35.1
Cerebellum34.95
CerebellumPeduncles96.15
CiliaryGanglion19.05
CingulateCortex71.45
Colorectaladenocarcinoma28.35
DorsalRootGanglion25.85
FetalThyroid30.65
Fetalbrain35.25
Fetalliver35.85
Fetallung21.65
GlobusPallidus84.05
Heart47.25
Hypothalamus39.95
Kidney33.8
Leukemia_chronicMyelogenousK-56231.45
Leukemia_promyelocytic-HL-6022.3
Leukemialymphoblastic(MOLT-4)28.35
Liver112.9
Lung45.05
Lymphnode28.1
Lymphoma_burkitts(Daudi)47.45
Lymphoma_burkitts(Raji)41.65
MedullaOblongata48.6
OccipitalLobe36.05
OlfactoryBulb26.25
Ovary23.35
Pancreas25.9
PancreaticIslet29.85
ParietalLobe53.95
Pituitary54.8
Placenta37.45
Pons70
PrefrontalCortex43.2
Prostate48.85
Salivarygland32.5
SkeletalMuscle69.9
Skin27.2
SmoothMuscle26.1
Spinalcord32.1
SubthalamicNucleus78.5
SuperiorCervicalGanglion44.5
TemporalLobe68.1
Testis54.5
TestisGermCell51.1
TestisIntersitial83.45
TestisLeydigCell49.3
TestisSeminiferousTubule61.05
Thalamus66.15
Thymus29.55
Thyroid38.6
Tongue38.9
Tonsil39.9
Trachea28.8
TrigeminalGanglion35.15
Uterus27.6
UterusCorpus31.25
WholeBlood33.4
Wholebrain28.05
colon35.65
pineal_day40.08
pineal_night35.92
retina42.275
small_intestine34.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1218_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.49 ± 0.58
Basal Forebrain4.07 ± 0.51
Basal Part of Pons3.88 ± 0.46
Cerebellar Cortex4.32 ± 0.51
Cerebellar Nuclei3.95 ± 0.66
Claustrum4.7 ± 0.76
Epithalamus3.6 ± 0.62
Frontal Lobe3.99 ± 0.66
Globus Pallidus4.06 ± 1.02
Hypothalamus3.96 ± 0.35
Insula3.76 ± 0.48
Limbic Lobe4.37 ± 0.66
Mesencephalon4.18 ± 0.78
Myelencephalon4.15 ± 0.65
Occipital Lobe4.31 ± 0.74
Parietal Lobe4.2 ± 0.67
Pontine Tegmentum4.05 ± 0.63
Striatum4.12 ± 0.62
Subthalamus4.1 ± 0.58
Temporal Lobe4.13 ± 0.65
Thalamus3.89 ± 0.67
White Matter3.47 ± 0.83
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp574CBCerebellum29.25
36.89
Zfp574CTXCerebral cortex18.51
12.04
Zfp574HIPHippocampal region9.45
7.99
Zfp574HPFHippocampal formation9.98
7.85
Zfp574HYHypothalamus2.04
1.53
Zfp574LSXLateral septal complex0.39
0.31
Zfp574MBMidbrain6.81
6.07
Zfp574MYMedulla12.25
11.06
Zfp574OLFOlfactory bulb13.15
10.21
Zfp574PPons4.43
4.04
Zfp574PALPallidum3.98
3.23
Zfp574RHPRetrohippocampal region10.72
7.53
Zfp574sAMYStriatum-like amygdalar nuclei5.25
3.96
Zfp574STRStriatum8.02
5.39
Zfp574STRdStriatum dorsal region8.36
5.68
Zfp574STRvStriatum ventral region11.79
7.19
Zfp574THThalamus6.34
4.94
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00073861 19 772 790 LQAHEAAHAAAGPGEVLAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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