AutismKB 2.0

Annotation Detail for CREB3L2


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Basic Information Top
Gene Symbol:CREB3L2 ( BBF2H7,MGC131709,MGC71006 )
Gene Full Name: cAMP responsive element binding protein 3-like 2
Band: 7q33
Quick LinksEntrez ID:64764; OMIM: 608834; Uniprot ID:CR3L2_HUMAN; ENSEMBL ID: ENSG00000182158; HGNC ID: 23720
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body18 / 70761254
blastocyst4 / 6231964
fetus20 / 56401235
neonate2 / 3109764
infant0 / 236200 
juvenile3 / 5555653
adult132 / 193912168
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma12 / 82823144
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor12 / 26384545
glioma3 / 10688328
head and neck tumor10 / 13630273
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor17 / 96359176
lung tumor5 / 10312748
lymphoma1 / 7175513
non-neoplasia10 / 97250102
normal180 / 336030753
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor11 / 12494988
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone7 / 7165597
bone marrow1 / 4880120
brain20 / 110098918
cervix3 / 4817162
connective tissue15 / 149255100
ear0 / 162120 
embryonic tissue25 / 215722115
esophagus1 / 2020949
eye10 / 21105447
heart0 / 896260 
intestine5 / 23447221
kidney5 / 21177723
larynx1 / 2414541
liver18 / 20774386
lung16 / 33697447
lymph1 / 4427022
lymph node1 / 9161010
mammary gland1 / 1532716
mouth4 / 6705259
muscle6 / 10771555
nerve4 / 15768253
ovary3 / 10205129
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta46 / 280825163
prostate7 / 18934536
salivary gland0 / 201550 
skin18 / 21057485
spleen2 / 5395237
stomach3 / 9661931
testis8 / 33044224
thymus6 / 8113173
thyroid9 / 47473189
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus17 / 23287872
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212345_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts157.6
Adipocyte25.65
AdrenalCortex118.75
Adrenalgland116
Amygdala13.2
Appendix17.45
AtrioventricularNode13
BDCA4+_DentriticCells335.95
Bonemarrow23.55
BronchialEpithelialCells30.7
CD105+_Endothelial18.05
CD14+_Monocytes35.75
CD19+_BCells(neg._sel.)67.1
CD33+_Myeloid70.15
CD34+187.65
CD4+_Tcells28.35
CD56+_NKCells143.15
CD71+_EarlyErythroid8.85
CD8+_Tcells51.95
CardiacMyocytes66.6
Caudatenucleus11.45
Cerebellum11.1
CerebellumPeduncles16.05
CiliaryGanglion12.05
CingulateCortex14.5
Colorectaladenocarcinoma10.5
DorsalRootGanglion12.85
FetalThyroid148.65
Fetalbrain8.85
Fetalliver24.9
Fetallung37.1
GlobusPallidus7.65
Heart16.2
Hypothalamus18
Kidney32.65
Leukemia_chronicMyelogenousK-56221.7
Leukemia_promyelocytic-HL-607.3
Leukemialymphoblastic(MOLT-4)11.8
Liver9.5
Lung38.35
Lymphnode32.1
Lymphoma_burkitts(Daudi)17.8
Lymphoma_burkitts(Raji)4.1
MedullaOblongata13.85
OccipitalLobe9.85
OlfactoryBulb97.65
Ovary32.3
Pancreas25.5
PancreaticIslet107.85
ParietalLobe13.45
Pituitary184.95
Placenta1278.85
Pons14.85
PrefrontalCortex21.75
Prostate54.75
Salivarygland73.6
SkeletalMuscle9.2
Skin11.5
SmoothMuscle154.25
Spinalcord18.1
SubthalamicNucleus13.9
SuperiorCervicalGanglion19.3
TemporalLobe11.7
Testis11.95
TestisGermCell12.6
TestisIntersitial10.7
TestisLeydigCell14.45
TestisSeminiferousTubule13
Thalamus12.5
Thymus21.5
Thyroid354.25
Tongue14.45
Tonsil48.05
Trachea73.85
TrigeminalGanglion14.85
Uterus123.2
UterusCorpus27.2
WholeBlood19.1
Wholebrain10.85
colon23
pineal_day57.7
pineal_night78.08
retina63
small_intestine103.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1388_PI416379584
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.19 ± 0.41
Basal Forebrain7.92 ± 0.34
Basal Part of Pons7.28 ± 0.29
Cerebellar Cortex7.19 ± 0.15
Cerebellar Nuclei8.05 ± 0.29
Claustrum7.55 ± 0.47
Epithalamus7.93 ± 0.34
Frontal Lobe7.42 ± 0.39
Globus Pallidus8.67 ± 0.28
Hypothalamus7.76 ± 0.36
Insula7.37 ± 0.21
Limbic Lobe7.31 ± 0.43
Mesencephalon7.8 ± 0.31
Myelencephalon7.64 ± 0.39
Occipital Lobe7.84 ± 0.52
Parietal Lobe7.48 ± 0.37
Pontine Tegmentum7.6 ± 0.46
Striatum8.29 ± 0.48
Subthalamus8.11 ± 0.15
Temporal Lobe7.38 ± 0.3
Thalamus7.85 ± 0.33
White Matter9.04 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Creb3l2CBCerebellum1.36
2.25
Creb3l2CTXCerebral cortex0.84
0.81
Creb3l2HIPHippocampal region1.38
1.59
Creb3l2HPFHippocampal formation1.05
1.1
Creb3l2HYHypothalamus1.33
1.02
Creb3l2LSXLateral septal complex0.29
0.24
Creb3l2MBMidbrain0.84
0.82
Creb3l2MYMedulla4.28
7.21
Creb3l2OLFOlfactory bulb2.79
2.76
Creb3l2PPons1.26
1.39
Creb3l2PALPallidum0.52
0.39
Creb3l2RHPRetrohippocampal region0.44
0.31
Creb3l2sAMYStriatum-like amygdalar nuclei0.54
0.39
Creb3l2STRStriatum0.76
0.59
Creb3l2STRdStriatum dorsal region0.78
0.66
Creb3l2STRvStriatum ventral region1.09
0.69
Creb3l2THThalamus0.74
0.52
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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