AutismKB 2.0

Annotation Detail for IPPK


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IPPK ( C9orf12,FLJ13163,INSP5K2,IP5K,IPK1,KIAA0699,bA476B13.1 )
Gene Full Name: inositol 1,3,4,5,6-pentakisphosphate 2-kinase
Band: 9q22.31
Quick LinksEntrez ID:64768; OMIM: NA; Uniprot ID:IPPK_HUMAN; ENSEMBL ID: ENSG00000127080; HGNC ID: 14645
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus5 / 5640128
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult33 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal60 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain19 / 110098917
cervix4 / 4817183
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye4 / 21105418
heart2 / 8962622
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node5 / 9161054
mammary gland3 / 15327119
mouth5 / 6705274
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta5 / 28082517
prostate6 / 18934531
salivary gland0 / 201550 
skin8 / 21057437
spleen1 / 5395218
stomach2 / 9661920
testis16 / 33044248
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219092_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.2
Adipocyte11.95
AdrenalCortex16.5
Adrenalgland10.6
Amygdala13.05
Appendix20.4
AtrioventricularNode13.85
BDCA4+_DentriticCells9.65
Bonemarrow13.55
BronchialEpithelialCells16.85
CD105+_Endothelial12.45
CD14+_Monocytes12.8
CD19+_BCells(neg._sel.)10.85
CD33+_Myeloid13.8
CD34+13.9
CD4+_Tcells10.95
CD56+_NKCells14.5
CD71+_EarlyErythroid12.15
CD8+_Tcells11.6
CardiacMyocytes17.2
Caudatenucleus11.2
Cerebellum9.9
CerebellumPeduncles17.05
CiliaryGanglion10.9
CingulateCortex12.55
Colorectaladenocarcinoma12.3
DorsalRootGanglion13.6
FetalThyroid13.4
Fetalbrain12.3
Fetalliver10.55
Fetallung9.05
GlobusPallidus8.85
Heart15.5
Hypothalamus12.35
Kidney10.45
Leukemia_chronicMyelogenousK-56210.6
Leukemia_promyelocytic-HL-6010.4
Leukemialymphoblastic(MOLT-4)10.45
Liver17.05
Lung13.2
Lymphnode10.4
Lymphoma_burkitts(Daudi)15.65
Lymphoma_burkitts(Raji)19.1
MedullaOblongata10.5
OccipitalLobe11
OlfactoryBulb9.8
Ovary9.35
Pancreas11
PancreaticIslet13.15
ParietalLobe13.05
Pituitary15.3
Placenta11.7
Pons20.25
PrefrontalCortex15.4
Prostate14.2
Salivarygland9.8
SkeletalMuscle20.8
Skin19.5
SmoothMuscle13.9
Spinalcord12.85
SubthalamicNucleus12.15
SuperiorCervicalGanglion21.7
TemporalLobe12.05
Testis12.65
TestisGermCell11.2
TestisIntersitial12.8
TestisLeydigCell16.05
TestisSeminiferousTubule15.65
Thalamus12.55
Thymus9.55
Thyroid13.95
Tongue18.6
Tonsil14
Trachea10.15
TrigeminalGanglion23.75
Uterus9.5
UterusCorpus13.8
WholeBlood12.55
Wholebrain9.9
colon8.5
pineal_day13.5
pineal_night12.92
retina14.675
small_intestine8.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P119174
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.94 ± 0.38
Basal Forebrain6.9 ± 0.15
Basal Part of Pons7.35 ± 0.26
Cerebellar Cortex6.95 ± 0.25
Cerebellar Nuclei7.45 ± 0.35
Claustrum6.95 ± 0.59
Epithalamus6.53 ± 0.4
Frontal Lobe7.28 ± 0.3
Globus Pallidus6.5 ± 0.58
Hypothalamus7.13 ± 0.3
Insula7.32 ± 0.32
Limbic Lobe7.18 ± 0.46
Mesencephalon6.97 ± 0.36
Myelencephalon6.98 ± 0.47
Occipital Lobe6.63 ± 0.37
Parietal Lobe7 ± 0.4
Pontine Tegmentum7.14 ± 0.37
Striatum7.19 ± 0.37
Subthalamus7.55 ± 0.15
Temporal Lobe7.21 ± 0.39
Thalamus6.89 ± 0.36
White Matter6.57 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
IppkCBCerebellum14.11
13.92
IppkCTXCerebral cortex31.33
20.69
IppkHIPHippocampal region53.6
80.48
IppkHPFHippocampal formation43.92
53.41
IppkHYHypothalamus9.22
6.37
IppkLSXLateral septal complex19.49
13.2
IppkMBMidbrain14.88
13
IppkMYMedulla16.42
15.03
IppkOLFOlfactory bulb37.58
26.9
IppkPPons17
15.24
IppkPALPallidum17.52
12.83
IppkRHPRetrohippocampal region29.44
20.36
IppksAMYStriatum-like amygdalar nuclei14.79
9.31
IppkSTRStriatum55.32
37.42
IppkSTRdStriatum dorsal region64.87
44.37
IppkSTRvStriatum ventral region65.65
42.55
IppkTHThalamus19.06
16.4
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved