AutismKB 2.0

Annotation Detail for FNDC3B


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Basic Information Top
Gene Symbol:FNDC3B ( DKFZp686D14170,DKFZp762K137,FAD104,FLJ23399,MGC10002,PRO4979,YVTM2421 )
Gene Full Name: fibronectin type III domain containing 3B
Band: 3q26.31
Quick LinksEntrez ID:64778; OMIM: 611909; Uniprot ID:FND3B_HUMAN; ENSEMBL ID: ENSG00000075420; HGNC ID: 24670
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst2 / 6231932
fetus55 / 56401297
neonate2 / 3109764
infant1 / 2362042
juvenile2 / 5555635
adult155 / 193912179
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor11 / 94178116
cervical tumor3 / 3436687
chondrosarcoma9 / 82823108
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor7 / 26384526
glioma2 / 10688318
head and neck tumor4 / 13630229
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor8 / 9635983
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal256 / 336030776
ovarian tumor5 / 7668265
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor16 / 90257177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland3 / 3319790
ascites1 / 4001524
bladder0 / 297570 
blood6 / 12347848
bone11 / 71655153
bone marrow2 / 4880140
brain15 / 110098913
cervix3 / 4817162
connective tissue12 / 14925580
ear4 / 16212246
embryonic tissue11 / 21572250
esophagus1 / 2020949
eye5 / 21105423
heart16 / 89626178
intestine16 / 23447268
kidney15 / 21177770
larynx1 / 2414541
liver13 / 20774362
lung22 / 33697465
lymph0 / 442700 
lymph node2 / 9161021
mammary gland28 / 153271182
mouth1 / 6705214
muscle5 / 10771546
nerve0 / 157680 
ovary6 / 10205158
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta48 / 280825170
prostate3 / 18934515
salivary gland1 / 2015549
skin17 / 21057480
spleen2 / 5395237
stomach5 / 9661951
testis7 / 33044221
thymus1 / 8113112
thyroid5 / 47473105
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus24 / 232878103
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218618_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.35
Adipocyte48.25
AdrenalCortex42.65
Adrenalgland28.75
Amygdala3.45
Appendix3.35
AtrioventricularNode2.7
BDCA4+_DentriticCells22.75
Bonemarrow3.4
BronchialEpithelialCells33.75
CD105+_Endothelial5.75
CD14+_Monocytes49.35
CD19+_BCells(neg._sel.)3.65
CD33+_Myeloid80.05
CD34+27.2
CD4+_Tcells4.4
CD56+_NKCells65.25
CD71+_EarlyErythroid3.1
CD8+_Tcells6.4
CardiacMyocytes63.1
Caudatenucleus2.95
Cerebellum2.65
CerebellumPeduncles3.7
CiliaryGanglion2.85
CingulateCortex3.35
Colorectaladenocarcinoma4.75
DorsalRootGanglion2.55
FetalThyroid45.8
Fetalbrain3.35
Fetalliver17.15
Fetallung15.1
GlobusPallidus2.45
Heart4.25
Hypothalamus3.65
Kidney3.8
Leukemia_chronicMyelogenousK-5623.1
Leukemia_promyelocytic-HL-603
Leukemialymphoblastic(MOLT-4)2.65
Liver4.6
Lung39.4
Lymphnode2.95
Lymphoma_burkitts(Daudi)4.25
Lymphoma_burkitts(Raji)4.65
MedullaOblongata3.05
OccipitalLobe3
OlfactoryBulb3.55
Ovary6.4
Pancreas38
PancreaticIslet51.35
ParietalLobe3.5
Pituitary14.7
Placenta337.55
Pons3.2
PrefrontalCortex4.3
Prostate14.75
Salivarygland2.7
SkeletalMuscle3.8
Skin2.5
SmoothMuscle397.15
Spinalcord3.5
SubthalamicNucleus2.95
SuperiorCervicalGanglion3.8
TemporalLobe3
Testis3.85
TestisGermCell12.15
TestisIntersitial3
TestisLeydigCell3.4
TestisSeminiferousTubule2.95
Thalamus3.35
Thymus2.9
Thyroid7
Tongue3.9
Tonsil3.35
Trachea13.95
TrigeminalGanglion3.45
Uterus60.15
UterusCorpus9.9
WholeBlood24.7
Wholebrain2.8
colon22.3
pineal_day4.86
pineal_night4.56
retina6.375
small_intestine13.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P253434
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.49 ± 0.24
Basal Forebrain6.58 ± 0.28
Basal Part of Pons6.08 ± 0.2
Cerebellar Cortex6.23 ± 0.28
Cerebellar Nuclei6.46 ± 0.34
Claustrum6.34 ± 0.39
Epithalamus7.07 ± 0.46
Frontal Lobe6.51 ± 0.33
Globus Pallidus7.12 ± 0.41
Hypothalamus6.89 ± 0.2
Insula6.52 ± 0.37
Limbic Lobe6.51 ± 0.45
Mesencephalon6.54 ± 0.3
Myelencephalon6.6 ± 0.43
Occipital Lobe6.6 ± 0.33
Parietal Lobe6.58 ± 0.36
Pontine Tegmentum6.71 ± 0.45
Striatum6.97 ± 0.24
Subthalamus6.47 ± 0.32
Temporal Lobe6.55 ± 0.28
Thalamus6.56 ± 0.35
White Matter6.51 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fndc3bCBCerebellum3.81
4.28
Fndc3bCTXCerebral cortex4.76
2.93
Fndc3bHIPHippocampal region5.54
5.42
Fndc3bHPFHippocampal formation4.6
3.92
Fndc3bHYHypothalamus1.92
1.51
Fndc3bLSXLateral septal complex5.14
3.68
Fndc3bMBMidbrain0.92
1.65
Fndc3bMYMedulla2.28
2.4
Fndc3bOLFOlfactory bulb9.23
5.59
Fndc3bPPons2.18
1.74
Fndc3bPALPallidum2.01
1.53
Fndc3bRHPRetrohippocampal region2.96
1.89
Fndc3bsAMYStriatum-like amygdalar nuclei4.95
3.12
Fndc3bSTRStriatum3.67
2.07
Fndc3bSTRdStriatum dorsal region3.03
1.7
Fndc3bSTRvStriatum ventral region4.07
1.94
Fndc3bTHThalamus2.59
1.99
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00513488 19 272 290 VQDILSGIEKPQVSNIQAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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