AutismKB 2.0

Annotation Detail for CRTC3


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Basic Information Top
Gene Symbol:CRTC3 ( FLJ21868,TORC3 )
Gene Full Name: CREB regulated transcription coactivator 3
Band: 15q26.1
Quick LinksEntrez ID:64784; OMIM: 608986; Uniprot ID:CRTC3_HUMAN; ENSEMBL ID: ENSG00000140577; HGNC ID: 26148
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus15 / 56401226
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult58 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor4 / 34366116
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor14 / 26384553
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor7 / 10312767
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal104 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow1 / 4880120
brain36 / 110098932
cervix9 / 48171186
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye15 / 21105471
heart4 / 8962644
intestine7 / 23447229
kidney8 / 21177737
larynx0 / 241450 
liver3 / 20774314
lung16 / 33697447
lymph0 / 442700 
lymph node3 / 9161032
mammary gland3 / 15327119
mouth3 / 6705244
muscle4 / 10771537
nerve1 / 1576863
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta21 / 28082574
prostate3 / 18934515
salivary gland1 / 2015549
skin2 / 2105749
spleen2 / 5395237
stomach5 / 9661951
testis12 / 33044236
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218648_at
Cell line Expression level Expression bar
721_B_lymphoblasts238.2
Adipocyte77.95
AdrenalCortex88.65
Adrenalgland100.4
Amygdala108.25
Appendix65.9
AtrioventricularNode84.6
BDCA4+_DentriticCells478.1
Bonemarrow47.65
BronchialEpithelialCells30.7
CD105+_Endothelial175.8
CD14+_Monocytes308.25
CD19+_BCells(neg._sel.)638.85
CD33+_Myeloid437.9
CD34+196.55
CD4+_Tcells778.9
CD56+_NKCells754.45
CD71+_EarlyErythroid35.4
CD8+_Tcells534.6
CardiacMyocytes36.6
Caudatenucleus142.75
Cerebellum96.2
CerebellumPeduncles79.2
CiliaryGanglion66.65
CingulateCortex84.75
Colorectaladenocarcinoma57.85
DorsalRootGanglion59.05
FetalThyroid241.45
Fetalbrain93.35
Fetalliver35.75
Fetallung219.65
GlobusPallidus29.3
Heart169.3
Hypothalamus199.2
Kidney49.9
Leukemia_chronicMyelogenousK-56238.75
Leukemia_promyelocytic-HL-6018.25
Leukemialymphoblastic(MOLT-4)55.25
Liver65
Lung374.7
Lymphnode188.1
Lymphoma_burkitts(Daudi)39
Lymphoma_burkitts(Raji)34.35
MedullaOblongata96.35
OccipitalLobe101.05
OlfactoryBulb176.4
Ovary98.35
Pancreas17.9
PancreaticIslet143.1
ParietalLobe90.65
Pituitary69.1
Placenta226.9
Pons30.25
PrefrontalCortex217.5
Prostate192.45
Salivarygland110.25
SkeletalMuscle40.85
Skin77.55
SmoothMuscle65.05
Spinalcord237.95
SubthalamicNucleus45.5
SuperiorCervicalGanglion101.25
TemporalLobe30.5
Testis273.95
TestisGermCell318.45
TestisIntersitial119.5
TestisLeydigCell83.65
TestisSeminiferousTubule136.65
Thalamus126.05
Thymus193.45
Thyroid409.6
Tongue45
Tonsil154.15
Trachea94.5
TrigeminalGanglion28.15
Uterus307
UterusCorpus75.95
WholeBlood135.15
Wholebrain102.75
colon90.15
pineal_day108.46
pineal_night147.9
retina397
small_intestine141.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5517_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.93 ± 0.25
Basal Forebrain6.05 ± 0.05
Basal Part of Pons5.73 ± 0.38
Cerebellar Cortex6.21 ± 0.23
Cerebellar Nuclei6.35 ± 0.39
Claustrum6.12 ± 0.4
Epithalamus5.62 ± 0.28
Frontal Lobe5.81 ± 0.37
Globus Pallidus6.49 ± 0.42
Hypothalamus5.46 ± 0.32
Insula5.68 ± 0.12
Limbic Lobe6.09 ± 0.51
Mesencephalon6.02 ± 0.5
Myelencephalon5.98 ± 0.45
Occipital Lobe6.44 ± 0.52
Parietal Lobe5.92 ± 0.44
Pontine Tegmentum6.05 ± 0.48
Striatum6.38 ± 0.52
Subthalamus6.08 ± 0.28
Temporal Lobe5.81 ± 0.34
Thalamus5.9 ± 0.39
White Matter7.41 ± 0.31
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00079641 26 340 365 TVLSSSLNNHPQTSVPNASALHPSLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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