AutismKB 2.0

Annotation Detail for LMF1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LMF1 ( C16orf26,FLJ12681,FLJ22302,HMFN1876,JFP11,TMEM112,TMEM112A )
Gene Full Name: lipase maturation factor 1
Band: 16p13.3
Quick LinksEntrez ID:64788; OMIM: 611761; Uniprot ID:LMF1_HUMAN; ENSEMBL ID: ENSG00000103227; HGNC ID: 14154
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus25 / 56401244
neonate1 / 3109732
infant0 / 236200 
juvenile4 / 5555671
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor14 / 26384553
glioma9 / 10688384
head and neck tumor2 / 13630214
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor5 / 9635951
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal143 / 336030742
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland4 / 33197120
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone1 / 7165513
bone marrow0 / 488010 
brain73 / 110098966
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye4 / 21105418
heart4 / 8962644
intestine7 / 23447229
kidney16 / 21177775
larynx0 / 241450 
liver6 / 20774328
lung7 / 33697420
lymph0 / 442700 
lymph node2 / 9161021
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate7 / 18934536
salivary gland1 / 2015549
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis22 / 33044266
thymus1 / 8113112
thyroid4 / 4747384
tonsil1 / 1699958
trachea6 / 52413114
umbilical cord0 / 136800 
uterus4 / 23287817
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 46142_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.2
Adipocyte14.65
AdrenalCortex28.8
Adrenalgland26.55
Amygdala21.8
Appendix17.1
AtrioventricularNode20.9
BDCA4+_DentriticCells15.25
Bonemarrow17.15
BronchialEpithelialCells12
CD105+_Endothelial15.75
CD14+_Monocytes16.65
CD19+_BCells(neg._sel.)15.2
CD33+_Myeloid16.7
CD34+17.9
CD4+_Tcells15.7
CD56+_NKCells18.7
CD71+_EarlyErythroid13.95
CD8+_Tcells15.1
CardiacMyocytes35.95
Caudatenucleus18.7
Cerebellum12.7
CerebellumPeduncles24.05
CiliaryGanglion20.2
CingulateCortex21.9
Colorectaladenocarcinoma13.25
DorsalRootGanglion15.4
FetalThyroid22.75
Fetalbrain13.1
Fetalliver14.15
Fetallung9.85
GlobusPallidus17.45
Heart49.75
Hypothalamus19.65
Kidney32.4
Leukemia_chronicMyelogenousK-56212.65
Leukemia_promyelocytic-HL-6012.4
Leukemialymphoblastic(MOLT-4)11.15
Liver155.6
Lung53.35
Lymphnode12.45
Lymphoma_burkitts(Daudi)20.2
Lymphoma_burkitts(Raji)27.9
MedullaOblongata11.95
OccipitalLobe15.3
OlfactoryBulb14.75
Ovary17.4
Pancreas17.15
PancreaticIslet18.5
ParietalLobe21.9
Pituitary19.25
Placenta12.5
Pons18
PrefrontalCortex20.55
Prostate50.15
Salivarygland14.4
SkeletalMuscle32.9
Skin16.25
SmoothMuscle17.65
Spinalcord37.8
SubthalamicNucleus24.65
SuperiorCervicalGanglion32.15
TemporalLobe15.3
Testis15.15
TestisGermCell10.55
TestisIntersitial12.25
TestisLeydigCell16.25
TestisSeminiferousTubule13.7
Thalamus18.55
Thymus11.55
Thyroid39.1
Tongue29.35
Tonsil16.3
Trachea13.8
TrigeminalGanglion18.5
Uterus13.5
UterusCorpus22.45
WholeBlood13.9
Wholebrain24.15
colon12.9
pineal_day19.04
pineal_night20.28
retina42.6
small_intestine14.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P88947
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.82 ± 0.61
Basal Forebrain4.01 ± 0.49
Basal Part of Pons3.82 ± 0.7
Cerebellar Cortex3.56 ± 0.46
Cerebellar Nuclei3.92 ± 0.49
Claustrum3.49 ± 0.56
Epithalamus4.07 ± 0.56
Frontal Lobe4.05 ± 0.51
Globus Pallidus3.89 ± 0.55
Hypothalamus3.8 ± 0.39
Insula3.84 ± 0.67
Limbic Lobe3.74 ± 0.61
Mesencephalon3.91 ± 0.52
Myelencephalon3.96 ± 0.55
Occipital Lobe3.72 ± 0.49
Parietal Lobe3.82 ± 0.57
Pontine Tegmentum3.82 ± 0.49
Striatum3.78 ± 0.53
Subthalamus4.09 ± 0.23
Temporal Lobe3.99 ± 0.5
Thalamus3.85 ± 0.54
White Matter4.77 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2400010G15RikCBCerebellum12.29
15.74
2400010G15RikCTXCerebral cortex21.32
16.2
2400010G15RikHIPHippocampal region15.39
14.66
2400010G15RikHPFHippocampal formation12.22
10.7
2400010G15RikHYHypothalamus5.43
5.1
2400010G15RikLSXLateral septal complex2.15
1.77
2400010G15RikMBMidbrain13.19
13.09
2400010G15RikMYMedulla12.39
15.15
2400010G15RikOLFOlfactory bulb8.91
7.92
2400010G15RikPPons9.48
11.93
2400010G15RikPALPallidum0.99
0.99
2400010G15RikRHPRetrohippocampal region5.65
4.19
2400010G15RiksAMYStriatum-like amygdalar nuclei2.48
1.7
2400010G15RikSTRStriatum3.86
2.92
2400010G15RikSTRdStriatum dorsal region4.5
3.36
2400010G15RikSTRvStriatum ventral region3.23
2.66
2400010G15RikTHThalamus2.95
2.86
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved