AutismKB 2.0

Annotation Detail for IL25


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Basic Information Top
Gene Symbol:IL25 ( IL17E )
Gene Full Name: interleukin 25
Band: 14q11.2
Quick LinksEntrez ID:64806; OMIM: 605658; Uniprot ID:IL25_HUMAN; ENSEMBL ID: ENSG00000166090; HGNC ID: 13765
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220971_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.5
Adipocyte4.55
AdrenalCortex5.8
Adrenalgland4.95
Amygdala4.8
Appendix4.75
AtrioventricularNode3.65
BDCA4+_DentriticCells4.85
Bonemarrow5.25
BronchialEpithelialCells4.5
CD105+_Endothelial4.6
CD14+_Monocytes4.85
CD19+_BCells(neg._sel.)4.8
CD33+_Myeloid5.7
CD34+5.65
CD4+_Tcells4.9
CD56+_NKCells5.3
CD71+_EarlyErythroid4.35
CD8+_Tcells4.3
CardiacMyocytes6.15
Caudatenucleus4.35
Cerebellum3.95
CerebellumPeduncles5.65
CiliaryGanglion3.4
CingulateCortex4.75
Colorectaladenocarcinoma4.65
DorsalRootGanglion3.7
FetalThyroid4.5
Fetalbrain5.6
Fetalliver4.05
Fetallung3.75
GlobusPallidus3.45
Heart6.05
Hypothalamus5
Kidney4.65
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-604.1
Leukemialymphoblastic(MOLT-4)3.7
Liver6.3
Lung5
Lymphnode3.95
Lymphoma_burkitts(Daudi)5.95
Lymphoma_burkitts(Raji)6.65
MedullaOblongata4.2
OccipitalLobe4.15
OlfactoryBulb3.65
Ovary3.1
Pancreas3.75
PancreaticIslet4.95
ParietalLobe5.05
Pituitary5.4
Placenta4.65
Pons6.75
PrefrontalCortex5.65
Prostate5.35
Salivarygland3.7
SkeletalMuscle5.65
Skin3.6
SmoothMuscle5.25
Spinalcord4.95
SubthalamicNucleus4.3
SuperiorCervicalGanglion5.5
TemporalLobe4.3
Testis5.2
TestisGermCell3.8
TestisIntersitial3.9
TestisLeydigCell4.6
TestisSeminiferousTubule3.95
Thalamus4.75
Thymus3.6
Thyroid5.75
Tongue4.7
Tonsil4.6
Trachea3.9
TrigeminalGanglion4.75
Uterus3.75
UterusCorpus4.25
WholeBlood5
Wholebrain3.85
colon4.6
pineal_day5.68
pineal_night5.54
retina5.575
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15966_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.05 ± 0.98
Basal Forebrain1.47 ± 0.2
Basal Part of Pons1.19 ± 0.36
Cerebellar Cortex1.42 ± 0.7
Cerebellar Nuclei1.77 ± 0.77
Claustrum2.43 ± 0.88
Epithalamus1.2 ± 0.7
Frontal Lobe1.44 ± 0.7
Globus Pallidus2.15 ± 0.61
Hypothalamus1.71 ± 0.66
Insula1.35 ± 0.47
Limbic Lobe1.5 ± 0.6
Mesencephalon1.67 ± 0.71
Myelencephalon1.56 ± 0.7
Occipital Lobe1.5 ± 0.66
Parietal Lobe1.5 ± 0.8
Pontine Tegmentum1.58 ± 0.7
Striatum1.68 ± 0.62
Subthalamus1.57 ± 0.57
Temporal Lobe1.44 ± 0.62
Thalamus1.55 ± 0.65
White Matter2.03 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Il25CBCerebellum12.76
18.58
Il25CTXCerebral cortex2.88
2.56
Il25HIPHippocampal region3.83
4.09
Il25HPFHippocampal formation3.58
3.97
Il25HYHypothalamus0.15
0.19
Il25LSXLateral septal complex0.21
0.19
Il25MBMidbrain0.55
1.04
Il25MYMedulla1.65
2.1
Il25OLFOlfactory bulb12.6
11.92
Il25PPons1.12
2.06
Il25PALPallidum1.47
1.35
Il25RHPRetrohippocampal region2.78
3.34
Il25sAMYStriatum-like amygdalar nuclei17.4
13.99
Il25STRStriatum3.4
3
Il25STRdStriatum dorsal region1.27
1.36
Il25STRvStriatum ventral region5
4.05
Il25THThalamus0.67
1.17
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018