AutismKB 2.0

Annotation Detail for YTHDC2


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Basic Information Top
Gene Symbol:YTHDC2 ( - )
Gene Full Name: YTH domain containing 2
Band: 5q22.2
Quick LinksEntrez ID:64848; OMIM: NA; Uniprot ID:YTDC2_HUMAN; ENSEMBL ID: ENSG00000047188; HGNC ID: 24721
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor3 / 3436687
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor7 / 26384526
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia5 / 9584252
liver tumor6 / 9635962
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal87 / 336030725
ovarian tumor5 / 7668265
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor27 / 125191215
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow1 / 4880120
brain22 / 110098919
cervix3 / 4817162
connective tissue27 / 149255180
ear2 / 16212123
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine8 / 23447234
kidney8 / 21177737
larynx0 / 241450 
liver10 / 20774348
lung10 / 33697429
lymph1 / 4427022
lymph node5 / 9161054
mammary gland6 / 15327139
mouth2 / 6705229
muscle6 / 10771555
nerve1 / 1576863
ovary5 / 10205148
pancreas7 / 21481232
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta4 / 28082514
prostate4 / 18934521
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach6 / 9661962
testis14 / 33044242
thymus4 / 8113149
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205836_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.45
Adipocyte6.25
AdrenalCortex7.9
Adrenalgland5.95
Amygdala7.25
Appendix8.3
AtrioventricularNode5.9
BDCA4+_DentriticCells7.85
Bonemarrow7.25
BronchialEpithelialCells6.9
CD105+_Endothelial7.15
CD14+_Monocytes7.85
CD19+_BCells(neg._sel.)8.2
CD33+_Myeloid16
CD34+9
CD4+_Tcells21.15
CD56+_NKCells8.25
CD71+_EarlyErythroid6.95
CD8+_Tcells19.45
CardiacMyocytes10.4
Caudatenucleus6.25
Cerebellum5.55
CerebellumPeduncles7.9
CiliaryGanglion5.65
CingulateCortex7.55
Colorectaladenocarcinoma6.55
DorsalRootGanglion5.5
FetalThyroid6.85
Fetalbrain7.3
Fetalliver6.15
Fetallung5.9
GlobusPallidus5.4
Heart9.95
Hypothalamus7.4
Kidney5.65
Leukemia_chronicMyelogenousK-5626.45
Leukemia_promyelocytic-HL-606.6
Leukemialymphoblastic(MOLT-4)6.3
Liver10
Lung7.15
Lymphnode9.25
Lymphoma_burkitts(Daudi)11.05
Lymphoma_burkitts(Raji)9.9
MedullaOblongata6.4
OccipitalLobe6.2
OlfactoryBulb5.55
Ovary26.15
Pancreas5.6
PancreaticIslet7.3
ParietalLobe7.35
Pituitary8.4
Placenta6.55
Pons7.4
PrefrontalCortex10.1
Prostate7.25
Salivarygland9.05
SkeletalMuscle8.6
Skin5.7
SmoothMuscle7.8
Spinalcord7.45
SubthalamicNucleus6.35
SuperiorCervicalGanglion9.7
TemporalLobe6.25
Testis5.6
TestisGermCell8.8
TestisIntersitial12.1
TestisLeydigCell7.45
TestisSeminiferousTubule6.2
Thalamus12.15
Thymus4.8
Thyroid8.2
Tongue6.8
Tonsil6.9
Trachea5.6
TrigeminalGanglion8.15
Uterus5.5
UterusCorpus6.55
WholeBlood7.15
Wholebrain4.9
colon6.6
pineal_day9.24
pineal_night14.34
retina8.575
small_intestine6.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P178106
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.3 ± 0.35
Basal Forebrain7.5 ± 0.14
Basal Part of Pons7.52 ± 0.2
Cerebellar Cortex7.73 ± 0.13
Cerebellar Nuclei7.46 ± 0.32
Claustrum7.39 ± 0.27
Epithalamus7.59 ± 0.13
Frontal Lobe7.53 ± 0.28
Globus Pallidus7.17 ± 0.22
Hypothalamus7.33 ± 0.22
Insula7.6 ± 0.23
Limbic Lobe7.58 ± 0.24
Mesencephalon7.49 ± 0.33
Myelencephalon7.48 ± 0.26
Occipital Lobe7.68 ± 0.17
Parietal Lobe7.55 ± 0.22
Pontine Tegmentum7.47 ± 0.27
Striatum7.27 ± 0.23
Subthalamus7.52 ± 0.26
Temporal Lobe7.53 ± 0.27
Thalamus7.45 ± 0.25
White Matter7.69 ± 0.14
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ythdc2CBCerebellum7.63
9.34
Ythdc2CTXCerebral cortex13.64
9.25
Ythdc2HIPHippocampal region11.36
10.82
Ythdc2HPFHippocampal formation10.24
9.02
Ythdc2HYHypothalamus1.9
1.4
Ythdc2LSXLateral septal complex3.83
2.46
Ythdc2MBMidbrain6.42
5.66
Ythdc2MYMedulla11.08
10.34
Ythdc2OLFOlfactory bulb12.24
8.82
Ythdc2PPons9.03
8.4
Ythdc2PALPallidum2.74
2.06
Ythdc2RHPRetrohippocampal region8.71
6.83
Ythdc2sAMYStriatum-like amygdalar nuclei2.03
1.14
Ythdc2STRStriatum4.24
2.82
Ythdc2STRdStriatum dorsal region4.36
3.03
Ythdc2STRvStriatum ventral region5.26
3.14
Ythdc2THThalamus6.17
5.06
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010773 15 782 796 LLAPVNCPIADFLMK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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