Annotation Detail for USP46
Basic Information Top
Gene Symbol: | USP46 ( FLJ11850,FLJ12552,FLJ14283,FLJ39393 ) |
---|---|
Gene Full Name: | ubiquitin specific peptidase 46 |
Band: | 4q12 |
Quick Links | Entrez ID:64854; OMIM: 612849; Uniprot ID:UBP46_HUMAN; ENSEMBL ID: ENSG00000109189; HGNC ID: 20075 |
Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.7966
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
embryoid body | 3 / 70761 | 42 | |
blastocyst | 4 / 62319 | 64 | |
fetus | 44 / 564012 | 78 | |
neonate | 0 / 31097 | 0 | |
infant | 0 / 23620 | 0 | |
juvenile | 2 / 55556 | 35 | |
adult | 80 / 1939121 | 41 |
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
adrenal tumor | 0 / 12794 | 0 | |
bladder carcinoma | 0 / 17475 | 0 | |
breast (mammary gland) tumor | 1 / 94178 | 10 | |
cervical tumor | 2 / 34366 | 58 | |
chondrosarcoma | 3 / 82823 | 36 | |
colorectal tumor | 0 / 114246 | 0 | |
esophageal tumor | 0 / 17290 | 0 | |
gastrointestinal tumor | 10 / 119369 | 83 | |
germ cell tumor | 15 / 263845 | 56 | |
glioma | 6 / 106883 | 56 | |
head and neck tumor | 4 / 136302 | 29 | |
kidney tumor | 1 / 68959 | 14 | |
leukemia | 0 / 95842 | 0 | |
liver tumor | 1 / 96359 | 10 | |
lung tumor | 2 / 103127 | 19 | |
lymphoma | 0 / 71755 | 0 | |
non-neoplasia | 3 / 97250 | 30 | |
normal | 214 / 3360307 | 63 | |
ovarian tumor | 1 / 76682 | 13 | |
pancreatic tumor | 0 / 104616 | 0 | |
primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
prostate cancer | 1 / 102680 | 9 | |
retinoblastoma | 0 / 46356 | 0 | |
skin tumor | 1 / 124949 | 8 | |
soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
uterine tumor | 3 / 90257 | 33 |
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
adipose tissue | 0 / 13106 | 0 | |
adrenal gland | 1 / 33197 | 30 | |
ascites | 0 / 40015 | 0 | |
bladder | 1 / 29757 | 33 | |
blood | 0 / 123478 | 0 | |
bone | 1 / 71655 | 13 | |
bone marrow | 0 / 48801 | 0 | |
brain | 115 / 1100989 | 104 | |
cervix | 2 / 48171 | 41 | |
connective tissue | 4 / 149255 | 26 | |
ear | 0 / 16212 | 0 | |
embryonic tissue | 12 / 215722 | 55 | |
esophagus | 0 / 20209 | 0 | |
eye | 3 / 211054 | 14 | |
heart | 1 / 89626 | 11 | |
intestine | 0 / 234472 | 0 | |
kidney | 5 / 211777 | 23 | |
larynx | 0 / 24145 | 0 | |
liver | 2 / 207743 | 9 | |
lung | 9 / 336974 | 26 | |
lymph | 0 / 44270 | 0 | |
lymph node | 2 / 91610 | 21 | |
mammary gland | 6 / 153271 | 39 | |
mouth | 3 / 67052 | 44 | |
muscle | 4 / 107715 | 37 | |
nerve | 0 / 15768 | 0 | |
ovary | 1 / 102051 | 9 | |
pancreas | 0 / 214812 | 0 | |
parathyroid | 2 / 20539 | 97 | |
pharynx | 1 / 41328 | 24 | |
pituitary gland | 0 / 16585 | 0 | |
placenta | 17 / 280825 | 60 | |
prostate | 3 / 189345 | 15 | |
salivary gland | 0 / 20155 | 0 | |
skin | 3 / 210574 | 14 | |
spleen | 1 / 53952 | 18 | |
stomach | 10 / 96619 | 103 | |
testis | 28 / 330442 | 84 | |
thymus | 2 / 81131 | 24 | |
thyroid | 2 / 47473 | 42 | |
tonsil | 0 / 16999 | 0 | |
trachea | 4 / 52413 | 76 | |
umbilical cord | 0 / 13680 | 0 | |
uterus | 9 / 232878 | 38 | |
vascular | 3 / 51780 | 57 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 203870_at
Cell line | Expression level | Expression bar |
---|---|---|
721_B_lymphoblasts | 8.6 | |
Adipocyte | 7.15 | |
AdrenalCortex | 9.5 | |
Adrenalgland | 6.8 | |
Amygdala | 210.5 | |
Appendix | 9.25 | |
AtrioventricularNode | 30.95 | |
BDCA4+_DentriticCells | 7.35 | |
Bonemarrow | 8.15 | |
BronchialEpithelialCells | 7.9 | |
CD105+_Endothelial | 8.85 | |
CD14+_Monocytes | 7.8 | |
CD19+_BCells(neg._sel.) | 7.35 | |
CD33+_Myeloid | 9.05 | |
CD34+ | 11.8 | |
CD4+_Tcells | 7.4 | |
CD56+_NKCells | 8.45 | |
CD71+_EarlyErythroid | 7 | |
CD8+_Tcells | 6.1 | |
CardiacMyocytes | 13.2 | |
Caudatenucleus | 27.8 | |
Cerebellum | 38.8 | |
CerebellumPeduncles | 16.65 | |
CiliaryGanglion | 6.8 | |
CingulateCortex | 32 | |
Colorectaladenocarcinoma | 7.05 | |
DorsalRootGanglion | 14.75 | |
FetalThyroid | 7.65 | |
Fetalbrain | 54.55 | |
Fetalliver | 6.75 | |
Fetallung | 5.55 | |
GlobusPallidus | 23.85 | |
Heart | 12.7 | |
Hypothalamus | 85.2 | |
Kidney | 6.8 | |
Leukemia_chronicMyelogenousK-562 | 6.45 | |
Leukemia_promyelocytic-HL-60 | 6.4 | |
Leukemialymphoblastic(MOLT-4) | 5.75 | |
Liver | 11.5 | |
Lung | 7.75 | |
Lymphnode | 5.9 | |
Lymphoma_burkitts(Daudi) | 9.65 | |
Lymphoma_burkitts(Raji) | 11.5 | |
MedullaOblongata | 34.85 | |
OccipitalLobe | 45 | |
OlfactoryBulb | 115.4 | |
Ovary | 5.6 | |
Pancreas | 6.15 | |
PancreaticIslet | 8.1 | |
ParietalLobe | 13.5 | |
Pituitary | 8.75 | |
Placenta | 9.8 | |
Pons | 8.65 | |
PrefrontalCortex | 189.05 | |
Prostate | 8.4 | |
Salivarygland | 6.45 | |
SkeletalMuscle | 11.35 | |
Skin | 7.85 | |
SmoothMuscle | 8.4 | |
Spinalcord | 49 | |
SubthalamicNucleus | 25.9 | |
SuperiorCervicalGanglion | 11.6 | |
TemporalLobe | 11.05 | |
Testis | 6.25 | |
TestisGermCell | 5.85 | |
TestisIntersitial | 6.3 | |
TestisLeydigCell | 7.75 | |
TestisSeminiferousTubule | 5.95 | |
Thalamus | 19.65 | |
Thymus | 5.35 | |
Thyroid | 8.8 | |
Tongue | 8.55 | |
Tonsil | 7.3 | |
Trachea | 6.15 | |
TrigeminalGanglion | 10.4 | |
Uterus | 7.3 | |
UterusCorpus | 7.6 | |
WholeBlood | 7.7 | |
Wholebrain | 100.9 | |
colon | 7.05 | |
pineal_day | 158.02 | |
pineal_night | 176.68 | |
retina | 22.6 | |
small_intestine | 6.8 |
Human Whole Brain Microarrayview in Allen Brain Atlas
- Probe name: A_23_P81180
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue | Expression(mean ± stddev) | Expression Bar |
---|---|---|
Amygdala | 8.19 ± 0.16 | |
Basal Forebrain | 8.02 ± 0.09 | |
Basal Part of Pons | 7.4 ± 0.2 | |
Cerebellar Cortex | 7.81 ± 0.3 | |
Cerebellar Nuclei | 7.53 ± 0.35 | |
Claustrum | 8.14 ± 0.34 | |
Epithalamus | 8.08 ± 0.39 | |
Frontal Lobe | 7.76 ± 0.25 | |
Globus Pallidus | 7.84 ± 0.18 | |
Hypothalamus | 7.77 ± 0.19 | |
Insula | 7.91 ± 0.2 | |
Limbic Lobe | 7.99 ± 0.35 | |
Mesencephalon | 7.87 ± 0.21 | |
Myelencephalon | 7.85 ± 0.31 | |
Occipital Lobe | 8 ± 0.3 | |
Parietal Lobe | 7.87 ± 0.28 | |
Pontine Tegmentum | 7.92 ± 0.21 | |
Striatum | 7.86 ± 0.23 | |
Subthalamus | 7.85 ± 0.08 | |
Temporal Lobe | 7.98 ± 0.25 | |
Thalamus | 7.73 ± 0.23 | |
White Matter | 7.14 ± 0.17 |
Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
---|---|---|---|---|
Usp46 | CB | Cerebellum | 23.67 | |
31.89 | ||||
Usp46 | CTX | Cerebral cortex | 64.27 | |
64.84 | ||||
Usp46 | HIP | Hippocampal region | 50 | |
88.2 | ||||
Usp46 | HPF | Hippocampal formation | 58.91 | |
87.4 | ||||
Usp46 | HY | Hypothalamus | 6.76 | |
5.94 | ||||
Usp46 | LSX | Lateral septal complex | 23.04 | |
22.77 | ||||
Usp46 | MB | Midbrain | 6.9 | |
7.35 | ||||
Usp46 | MY | Medulla | 12.72 | |
15.84 | ||||
Usp46 | OLF | Olfactory bulb | 69.56 | |
86.07 | ||||
Usp46 | P | Pons | 9.32 | |
11.49 | ||||
Usp46 | PAL | Pallidum | 10.96 | |
12.7 | ||||
Usp46 | RHP | Retrohippocampal region | 69.94 | |
80 | ||||
Usp46 | sAMY | Striatum-like amygdalar nuclei | 24.95 | |
26.24 | ||||
Usp46 | STR | Striatum | 11.51 | |
12.08 | ||||
Usp46 | STRd | Striatum dorsal region | 7.24 | |
8.75 | ||||
Usp46 | STRv | Striatum ventral region | 13.46 | |
11.04 | ||||
Usp46 | TH | Thalamus | 6.17 | |
7.24 |