Annotation Detail for PLEKHG2
Basic Information Top
| Gene Symbol: | PLEKHG2 ( ARHGEF42,CLG,DKFZp667J2325,FLJ00018,FLJ22458,FLJ38638 ) |
|---|---|
| Gene Full Name: | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 |
| Band: | 19q13.2 |
| Quick Links | Entrez ID:64857; OMIM: 611893; Uniprot ID:PKHG2_HUMAN; ENSEMBL ID: ENSG00000090924; HGNC ID: 29515 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.631574
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 11 / 564012 | 19 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 78 / 1939121 | 40 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 |  |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 6 / 114246 | 52 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 11 / 263845 | 41 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 1 / 95842 | 10 |  |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 11 / 103127 | 106 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 82 / 3360307 | 24 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 39 / 104616 | 372 |  |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 10 / 90257 | 110 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 1 / 29757 | 33 | |
| blood | 4 / 123478 | 32 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 16 / 1100989 | 14 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 14 / 215722 | 64 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 2 / 211054 | 9 | |
| heart | 0 / 89626 | 0 | |
| intestine | 7 / 234472 | 29 | |
| kidney | 12 / 211777 | 56 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 30 / 336974 | 89 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 10 / 91610 | 109 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 39 / 214812 | 181 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 9 / 280825 | 32 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 3 / 210574 | 14 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 2 / 96619 | 20 | |
| testis | 21 / 330442 | 63 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 13 / 232878 | 55 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_4992_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 1.95 ± 1.05 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.44 ± 0.2 | |
| Basal Part of Pons | 1.32 ± 0.41 | |
| Cerebellar Cortex | 1.52 ± 0.66 | |
| Cerebellar Nuclei | 1.8 ± 0.68 | |
| Claustrum | 2.18 ± 0.61 | |
| Epithalamus | 1.1 ± 0.77 | |
| Frontal Lobe | 1.44 ± 0.7 | |
| Globus Pallidus | 1.77 ± 0.43 | |
| Hypothalamus | 1.49 ± 0.73 | |
| Insula | 1.39 ± 0.65 | |
| Limbic Lobe | 1.59 ± 0.69 | |
| Mesencephalon | 1.7 ± 0.62 | |
| Myelencephalon | 1.53 ± 0.66 | |
| Occipital Lobe | 1.51 ± 0.57 | |
| Parietal Lobe | 1.55 ± 0.7 | |
| Pontine Tegmentum | 1.59 ± 0.66 | |
| Striatum | 1.59 ± 0.56 | |
| Subthalamus | 1.62 ± 0.56 | |
| Temporal Lobe | 1.48 ± 0.66 | |
| Thalamus | 1.53 ± 0.6 | |
| White Matter | 1.82 ± 0.14 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Plekhg2 | CB | Cerebellum | 18.2 | |
| 20.02 | | |||
| Plekhg2 | CTX | Cerebral cortex | 1.7 | |
| 1.52 | | |||
| Plekhg2 | HIP | Hippocampal region | 3.51 | |
| 3.23 | | |||
| Plekhg2 | HPF | Hippocampal formation | 2.74 | |
| 2.58 | | |||
| Plekhg2 | HY | Hypothalamus | 1.74 | |
| 1.41 | | |||
| Plekhg2 | LSX | Lateral septal complex | 4.99 | |
| 4.92 | | |||
| Plekhg2 | MB | Midbrain | 2.64 | |
| 3.01 | | |||
| Plekhg2 | MY | Medulla | 7.26 | |
| 6.87 | | |||
| Plekhg2 | OLF | Olfactory bulb | 11.48 | |
| 10.01 | | |||
| Plekhg2 | P | Pons | 6 | |
| 5.53 | | |||
| Plekhg2 | PAL | Pallidum | 1.42 | |
| 1.34 | | |||
| Plekhg2 | RHP | Retrohippocampal region | 1.78 | |
| 1.82 | | |||
| Plekhg2 | sAMY | Striatum-like amygdalar nuclei | 1.6 | |
| 1.65 | | |||
| Plekhg2 | STR | Striatum | 2.5 | |
| 2.13 | | |||
| Plekhg2 | STRd | Striatum dorsal region | 1.57 | |
| 1.35 | | |||
| Plekhg2 | STRv | Striatum ventral region | 4.04 | |
| 2.44 | | |||
| Plekhg2 | TH | Thalamus | 2.18 | |
| 2.09 | |