AutismKB 2.0

Annotation Detail for ST3GAL3


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Basic Information Top
Gene Symbol:ST3GAL3 ( SIAT6,ST3GALII,ST3GalIII,ST3N )
Gene Full Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 3
Band: 1p34.1
Quick LinksEntrez ID:6487; OMIM: 606494; Uniprot ID:SIAT6_HUMAN; ENSEMBL ID: ENSG00000126091; HGNC ID: 10866
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma4 / 10688337
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor5 / 9635951
lung tumor3 / 10312729
lymphoma3 / 7175541
non-neoplasia3 / 9725030
normal81 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain32 / 110098929
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine1 / 2344724
kidney7 / 21177733
larynx2 / 2414582
liver12 / 20774357
lung20 / 33697459
lymph3 / 4427067
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta3 / 28082510
prostate1 / 1893455
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach1 / 9661910
testis5 / 33044215
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P268123
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.39 ± 0.86
Basal Forebrain2.83 ± 0.36
Basal Part of Pons2.79 ± 0.25
Cerebellar Cortex3.19 ± 0.84
Cerebellar Nuclei3.53 ± 1.22
Claustrum3.5 ± 0.63
Epithalamus2.74 ± 0.86
Frontal Lobe3.15 ± 0.74
Globus Pallidus2.89 ± 0.44
Hypothalamus2.92 ± 0.5
Insula3.35 ± 0.68
Limbic Lobe2.99 ± 0.84
Mesencephalon3.21 ± 0.76
Myelencephalon3.1 ± 0.69
Occipital Lobe2.53 ± 0.72
Parietal Lobe3.19 ± 0.66
Pontine Tegmentum3.12 ± 0.75
Striatum2.83 ± 0.75
Subthalamus3.25 ± 0.82
Temporal Lobe3.14 ± 0.7
Thalamus3 ± 0.64
White Matter2.64 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
St3gal3CBCerebellum53.42
67.81
St3gal3CTXCerebral cortex82.14
62.72
St3gal3HIPHippocampal region66.95
67.32
St3gal3HPFHippocampal formation80.06
68.79
St3gal3HYHypothalamus51.91
32.78
St3gal3LSXLateral septal complex51.54
23.92
St3gal3MBMidbrain61.49
46.26
St3gal3MYMedulla70.66
73.57
St3gal3OLFOlfactory bulb86.65
70.75
St3gal3PPons68.39
70.53
St3gal3PALPallidum50.34
39.81
St3gal3RHPRetrohippocampal region82.8
70.35
St3gal3sAMYStriatum-like amygdalar nuclei47.13
27.3
St3gal3STRStriatum32.26
16.59
St3gal3STRdStriatum dorsal region22.9
11.64
St3gal3STRvStriatum ventral region50.13
23.99
St3gal3THThalamus57.53
40.19
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018