AutismKB 2.0

Annotation Detail for ST8SIA1


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Basic Information Top
Gene Symbol:ST8SIA1 ( GD3S,SIAT8,SIAT8A,ST8SiaI )
Gene Full Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Band: 12p12.1
Quick LinksEntrez ID:6489; OMIM: 601123; Uniprot ID:SIA8A_HUMAN; ENSEMBL ID: ENSG00000111728; HGNC ID: 10869
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult27 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal46 / 336030713
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma4 / 4635686
skin tumor7 / 12494956
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain22 / 110098919
cervix0 / 481710 
connective tissue0 / 1492550 
ear3 / 16212185
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye8 / 21105437
heart1 / 8962611
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas6 / 21481227
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland2 / 2015599
skin7 / 21057433
spleen0 / 539520 
stomach1 / 9661910
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210073_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.1
Adipocyte9.2
AdrenalCortex12.9
Adrenalgland8.45
Amygdala9.4
Appendix12.55
AtrioventricularNode11.75
BDCA4+_DentriticCells8.3
Bonemarrow10.5
BronchialEpithelialCells8.6
CD105+_Endothelial9.05
CD14+_Monocytes9.7
CD19+_BCells(neg._sel.)8.95
CD33+_Myeloid10.45
CD34+10.8
CD4+_Tcells9.25
CD56+_NKCells9.5
CD71+_EarlyErythroid8.95
CD8+_Tcells7.75
CardiacMyocytes17.15
Caudatenucleus8.45
Cerebellum9.15
CerebellumPeduncles13.65
CiliaryGanglion9.95
CingulateCortex11
Colorectaladenocarcinoma8.8
DorsalRootGanglion9.3
FetalThyroid9.3
Fetalbrain8.75
Fetalliver8.15
Fetallung6.45
GlobusPallidus7.85
Heart15.85
Hypothalamus9.9
Kidney9
Leukemia_chronicMyelogenousK-5628.35
Leukemia_promyelocytic-HL-608.1
Leukemialymphoblastic(MOLT-4)6.65
Liver15.15
Lung9.9
Lymphnode7.55
Lymphoma_burkitts(Daudi)12.35
Lymphoma_burkitts(Raji)14.7
MedullaOblongata8.3
OccipitalLobe8.25
OlfactoryBulb7.5
Ovary7.2
Pancreas8
PancreaticIslet9.95
ParietalLobe10.9
Pituitary10.65
Placenta8.3
Pons10.35
PrefrontalCortex11.5
Prostate10.6
Salivarygland8.4
SkeletalMuscle15.65
Skin10.25
SmoothMuscle9.95
Spinalcord9.8
SubthalamicNucleus10.4
SuperiorCervicalGanglion16.85
TemporalLobe9.95
Testis7.65
TestisGermCell6.95
TestisIntersitial7.95
TestisLeydigCell9.85
TestisSeminiferousTubule8.2
Thalamus11.25
Thymus6.5
Thyroid10.2
Tongue13.55
Tonsil9.4
Trachea7.85
TrigeminalGanglion15.8
Uterus7
UterusCorpus10.55
WholeBlood9.6
Wholebrain7.75
colon8.9
pineal_day106.84
pineal_night109.26
retina11.75
small_intestine8.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P354705
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.68 ± 0.55
Basal Forebrain7.32 ± 0.23
Basal Part of Pons7.22 ± 0.2
Cerebellar Cortex7.46 ± 0.12
Cerebellar Nuclei7.78 ± 0.3
Claustrum6.5 ± 0.38
Epithalamus7.99 ± 0.56
Frontal Lobe7.18 ± 0.39
Globus Pallidus7.26 ± 0.17
Hypothalamus7.23 ± 0.39
Insula7.01 ± 0.26
Limbic Lobe6.82 ± 0.45
Mesencephalon7.21 ± 0.45
Myelencephalon7.08 ± 0.5
Occipital Lobe7.32 ± 0.32
Parietal Lobe7.34 ± 0.41
Pontine Tegmentum7.25 ± 0.45
Striatum6.21 ± 0.49
Subthalamus7.84 ± 0.13
Temporal Lobe7.08 ± 0.39
Thalamus7.31 ± 0.43
White Matter5.28 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
St8sia1CBCerebellum40.58
67.67
St8sia1CTXCerebral cortex47.96
40.39
St8sia1HIPHippocampal region39.71
58.84
St8sia1HPFHippocampal formation46.48
53.34
St8sia1HYHypothalamus44.75
37.85
St8sia1LSXLateral septal complex19.53
14.51
St8sia1MBMidbrain60.37
62.34
St8sia1MYMedulla71.68
93.12
St8sia1OLFOlfactory bulb56.65
48.94
St8sia1PPons67.04
78.12
St8sia1PALPallidum54.31
58.91
St8sia1RHPRetrohippocampal region56.63
47.71
St8sia1sAMYStriatum-like amygdalar nuclei21.89
16.74
St8sia1STRStriatum15.94
12.07
St8sia1STRdStriatum dorsal region11.42
8.27
St8sia1STRvStriatum ventral region26.99
20.36
St8sia1THThalamus55.08
53.07
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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