AutismKB 2.0

Annotation Detail for BMP1


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Basic Information Top
Gene Symbol:BMP1 ( FLJ44432,PCOLC,PCP,PCP2,TLD )
Gene Full Name: bone morphogenetic protein 1
Band: 8p21.3
Quick LinksEntrez ID:649; OMIM: 112264; Uniprot ID:BMP1_HUMAN; ENSEMBL ID: ENSG00000168487; HGNC ID: 1067
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst1 / 6231916
fetus23 / 56401240
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult206 / 1939121106
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor3 / 3436687
chondrosarcoma9 / 82823108
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor7 / 11936958
germ cell tumor31 / 263845117
glioma5 / 10688346
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal219 / 336030765
ovarian tumor2 / 7668226
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer7 / 10268068
retinoblastoma1 / 4635621
skin tumor12 / 12494996
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites5 / 40015124
bladder1 / 2975733
blood0 / 1234780 
bone7 / 7165597
bone marrow1 / 4880120
brain36 / 110098932
cervix3 / 4817162
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus1 / 2020949
eye5 / 21105423
heart6 / 8962666
intestine12 / 23447251
kidney4 / 21177718
larynx2 / 2414582
liver1 / 2077434
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth4 / 6705259
muscle1 / 1077159
nerve1 / 1576863
ovary4 / 10205139
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta107 / 280825381
prostate13 / 18934568
salivary gland0 / 201550 
skin19 / 21057490
spleen0 / 539520 
stomach1 / 9661910
testis22 / 33044266
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus22 / 23287894
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202701_at
Cell line Expression level Expression bar
721_B_lymphoblasts27.05
Adipocyte39.4
AdrenalCortex49.7
Adrenalgland44.45
Amygdala32.25
Appendix34.25
AtrioventricularNode47.25
BDCA4+_DentriticCells28.5
Bonemarrow46.2
BronchialEpithelialCells48.9
CD105+_Endothelial30.9
CD14+_Monocytes29.35
CD19+_BCells(neg._sel.)28.15
CD33+_Myeloid39.7
CD34+34.5
CD4+_Tcells24.9
CD56+_NKCells33.4
CD71+_EarlyErythroid35.45
CD8+_Tcells20.95
CardiacMyocytes47.65
Caudatenucleus33.6
Cerebellum34.25
CerebellumPeduncles37.05
CiliaryGanglion35.45
CingulateCortex34.05
Colorectaladenocarcinoma31.35
DorsalRootGanglion28.7
FetalThyroid50.55
Fetalbrain33.35
Fetalliver33.2
Fetallung54.8
GlobusPallidus27.25
Heart39.55
Hypothalamus27.15
Kidney26.9
Leukemia_chronicMyelogenousK-56238.1
Leukemia_promyelocytic-HL-6028.65
Leukemialymphoblastic(MOLT-4)26.75
Liver43.6
Lung40.7
Lymphnode37.2
Lymphoma_burkitts(Daudi)44.3
Lymphoma_burkitts(Raji)45.15
MedullaOblongata35.7
OccipitalLobe34
OlfactoryBulb29.05
Ovary23.95
Pancreas28.2
PancreaticIslet35.1
ParietalLobe34.15
Pituitary38.8
Placenta396.3
Pons31.15
PrefrontalCortex31.45
Prostate37.75
Salivarygland25.85
SkeletalMuscle45.15
Skin29.5
SmoothMuscle86.7
Spinalcord41
SubthalamicNucleus37.55
SuperiorCervicalGanglion47.65
TemporalLobe29.85
Testis36.7
TestisGermCell24.95
TestisIntersitial18.55
TestisLeydigCell32.25
TestisSeminiferousTubule28.5
Thalamus33.05
Thymus25.7
Thyroid50.45
Tongue35.85
Tonsil35.05
Trachea27.05
TrigeminalGanglion40.5
Uterus47.6
UterusCorpus29
WholeBlood28.7
Wholebrain22.65
colon27.5
pineal_day33.8
pineal_night28
retina34.675
small_intestine15.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P60930
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.14 ± 1.14
Basal Forebrain1.79 ± 0.39
Basal Part of Pons1.44 ± 0.37
Cerebellar Cortex2.26 ± 0.72
Cerebellar Nuclei2.02 ± 0.87
Claustrum2.69 ± 0.98
Epithalamus1.84 ± 0.92
Frontal Lobe1.71 ± 0.84
Globus Pallidus2 ± 0.63
Hypothalamus1.71 ± 0.63
Insula1.39 ± 0.49
Limbic Lobe1.75 ± 0.71
Mesencephalon1.96 ± 0.73
Myelencephalon1.87 ± 0.72
Occipital Lobe1.94 ± 0.65
Parietal Lobe1.8 ± 0.77
Pontine Tegmentum1.95 ± 0.79
Striatum1.85 ± 0.82
Subthalamus1.94 ± 0.68
Temporal Lobe1.73 ± 0.74
Thalamus1.9 ± 0.69
White Matter2.65 ± 0.58
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Bmp1CBCerebellum2.69
3.29
Bmp1CTXCerebral cortex14.75
9.37
Bmp1HIPHippocampal region8.59
7.3
Bmp1HPFHippocampal formation6.55
5.1
Bmp1HYHypothalamus0.4
0.28
Bmp1LSXLateral septal complex0.64
0.41
Bmp1MBMidbrain0.53
0.52
Bmp1MYMedulla1.09
1.07
Bmp1OLFOlfactory bulb14.71
10.78
Bmp1PPons0.77
0.67
Bmp1PALPallidum1.01
0.74
Bmp1RHPRetrohippocampal region2.93
1.92
Bmp1sAMYStriatum-like amygdalar nuclei3.12
1.92
Bmp1STRStriatum1.64
1.12
Bmp1STRdStriatum dorsal region1.18
0.9
Bmp1STRvStriatum ventral region2.91
1.67
Bmp1THThalamus1.27
0.93
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00375694 16 49 64 AAAFLGDIALDEEDLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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