AutismKB 2.0

Annotation Detail for LPIN3


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Basic Information Top
Gene Symbol:LPIN3 ( LIPN3L,SMP2,dJ450M14.2,dJ450M14.3,dJ620E11.2 )
Gene Full Name: lipin 3
Band: 20q12
Quick LinksEntrez ID:64900; OMIM: 605520; Uniprot ID:LPIN3_HUMAN; ENSEMBL ID: ENSG00000132793; HGNC ID: 14451
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal33 / 33603079
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine4 / 23447217
kidney1 / 2117774
larynx1 / 2414541
liver4 / 20774319
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis3 / 3304429
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P100695
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.13 ± 0.96
Basal Forebrain3.81 ± 0.48
Basal Part of Pons3.43 ± 0.78
Cerebellar Cortex3.24 ± 0.74
Cerebellar Nuclei3.55 ± 0.72
Claustrum4.52 ± 0.78
Epithalamus3.11 ± 0.84
Frontal Lobe3.61 ± 0.79
Globus Pallidus4.48 ± 0.41
Hypothalamus3.12 ± 0.58
Insula3.22 ± 0.58
Limbic Lobe3.88 ± 0.87
Mesencephalon3.68 ± 0.79
Myelencephalon3.77 ± 0.86
Occipital Lobe3.75 ± 0.87
Parietal Lobe3.62 ± 0.91
Pontine Tegmentum3.68 ± 0.79
Striatum4.07 ± 0.88
Subthalamus3.19 ± 1.36
Temporal Lobe3.5 ± 0.83
Thalamus3.66 ± 0.64
White Matter4.14 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lpin3CBCerebellum4.23
5.22
Lpin3CTXCerebral cortex7.95
6.43
Lpin3HIPHippocampal region3.87
3.29
Lpin3HPFHippocampal formation3.5
2.99
Lpin3HYHypothalamus0.37
0.29
Lpin3LSXLateral septal complex0.02
0
Lpin3MBMidbrain0.84
1.07
Lpin3MYMedulla1.27
1.52
Lpin3OLFOlfactory bulb3
2
Lpin3PPons1.86
2.26
Lpin3PALPallidum0.91
0.75
Lpin3RHPRetrohippocampal region2.92
2.58
Lpin3sAMYStriatum-like amygdalar nuclei2.94
1.89
Lpin3STRStriatum1.34
1.07
Lpin3STRdStriatum dorsal region1.15
0.98
Lpin3STRvStriatum ventral region1.53
1.21
Lpin3THThalamus0.97
0.84
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018