AutismKB 2.0

Annotation Detail for NT5DC2


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Basic Information Top
Gene Symbol:NT5DC2 ( FLJ12442 )
Gene Full Name: 5'-nucleotidase domain containing 2
Band: 3p21.1
Quick LinksEntrez ID:64943; OMIM: NA; Uniprot ID:NT5D2_HUMAN; ENSEMBL ID: ENSG00000168268; HGNC ID: 25717
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body17 / 70761240
blastocyst0 / 623190 
fetus32 / 56401256
neonate4 / 31097128
infant2 / 2362084
juvenile0 / 555560 
adult124 / 193912163
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor2 / 3436658
chondrosarcoma8 / 8282396
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor13 / 119369108
germ cell tumor7 / 26384526
glioma8 / 10688374
head and neck tumor14 / 136302102
kidney tumor6 / 6895987
leukemia1 / 9584210
liver tumor15 / 96359155
lung tumor5 / 10312748
lymphoma4 / 7175555
non-neoplasia5 / 9725051
normal177 / 336030752
ovarian tumor9 / 76682117
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer10 / 10268097
retinoblastoma5 / 46356107
skin tumor7 / 12494956
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites12 / 40015299
bladder0 / 297570 
blood6 / 12347848
bone5 / 7165569
bone marrow3 / 4880161
brain47 / 110098942
cervix2 / 4817141
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue22 / 215722101
esophagus0 / 202090 
eye22 / 211054104
heart6 / 8962666
intestine10 / 23447242
kidney7 / 21177733
larynx4 / 24145165
liver17 / 20774381
lung17 / 33697450
lymph4 / 4427090
lymph node2 / 9161021
mammary gland5 / 15327132
mouth0 / 670520 
muscle6 / 10771555
nerve0 / 157680 
ovary12 / 102051117
pancreas9 / 21481241
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta20 / 28082571
prostate14 / 18934573
salivary gland2 / 2015599
skin12 / 21057456
spleen1 / 5395218
stomach0 / 966190 
testis9 / 33044227
thymus0 / 811310 
thyroid10 / 47473210
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord3 / 13680219
uterus4 / 23287817
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218051_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts204.55
Adipocyte9.2
AdrenalCortex4.75
Adrenalgland5.7
Amygdala4.7
Appendix4.45
AtrioventricularNode3.4
BDCA4+_DentriticCells14.75
Bonemarrow4.35
BronchialEpithelialCells181.4
CD105+_Endothelial4.6
CD14+_Monocytes4.7
CD19+_BCells(neg._sel.)4.65
CD33+_Myeloid5.8
CD34+22.8
CD4+_Tcells4.7
CD56+_NKCells5.35
CD71+_EarlyErythroid4.15
CD8+_Tcells4.2
CardiacMyocytes242.35
Caudatenucleus4
Cerebellum3.65
CerebellumPeduncles5.1
CiliaryGanglion3.1
CingulateCortex4.5
Colorectaladenocarcinoma12.1
DorsalRootGanglion3.35
FetalThyroid4.9
Fetalbrain5.95
Fetalliver5.5
Fetallung7.75
GlobusPallidus3.3
Heart10.1
Hypothalamus5
Kidney3.65
Leukemia_chronicMyelogenousK-56275.1
Leukemia_promyelocytic-HL-6041.45
Leukemialymphoblastic(MOLT-4)6
Liver5.85
Lung5.5
Lymphnode3.8
Lymphoma_burkitts(Daudi)117.35
Lymphoma_burkitts(Raji)7.5
MedullaOblongata4
OccipitalLobe4.05
OlfactoryBulb3.55
Ovary2.95
Pancreas3.6
PancreaticIslet4.7
ParietalLobe4.7
Pituitary5.5
Placenta5.9
Pons4.25
PrefrontalCortex5.55
Prostate7.95
Salivarygland3.6
SkeletalMuscle5.2
Skin3.4
SmoothMuscle146
Spinalcord4.8
SubthalamicNucleus3.9
SuperiorCervicalGanglion5
TemporalLobe4.1
Testis3.95
TestisGermCell5.1
TestisIntersitial3.75
TestisLeydigCell4.45
TestisSeminiferousTubule3.9
Thalamus4.55
Thymus3.5
Thyroid7.25
Tongue4.35
Tonsil4.35
Trachea3.75
TrigeminalGanglion4.4
Uterus3.7
UterusCorpus3.95
WholeBlood4.85
Wholebrain3.8
colon4.5
pineal_day5.42
pineal_night5.38
retina7.8
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6570_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.16 ± 1.19
Basal Forebrain1.59 ± 0.22
Basal Part of Pons1.32 ± 0.38
Cerebellar Cortex1.59 ± 0.86
Cerebellar Nuclei1.91 ± 0.67
Claustrum2.67 ± 1.06
Epithalamus1.35 ± 0.66
Frontal Lobe1.49 ± 0.67
Globus Pallidus2.38 ± 0.43
Hypothalamus1.66 ± 0.53
Insula1.52 ± 0.58
Limbic Lobe1.65 ± 0.71
Mesencephalon1.77 ± 0.65
Myelencephalon1.7 ± 0.72
Occipital Lobe1.74 ± 0.63
Parietal Lobe1.7 ± 0.81
Pontine Tegmentum1.8 ± 0.86
Striatum1.82 ± 0.9
Subthalamus1.73 ± 0.7
Temporal Lobe1.53 ± 0.66
Thalamus1.61 ± 0.63
White Matter1.98 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nt5dc2CBCerebellum1.34
1.66
Nt5dc2CTXCerebral cortex0.87
0.8
Nt5dc2HIPHippocampal region1.51
1.49
Nt5dc2HPFHippocampal formation1.5
1.39
Nt5dc2HYHypothalamus0.86
1.05
Nt5dc2LSXLateral septal complex1.44
1.8
Nt5dc2MBMidbrain0.32
0.5
Nt5dc2MYMedulla2.12
3.24
Nt5dc2OLFOlfactory bulb2.59
3.02
Nt5dc2PPons1.36
2.12
Nt5dc2PALPallidum0.47
0.43
Nt5dc2RHPRetrohippocampal region1.56
1.35
Nt5dc2sAMYStriatum-like amygdalar nuclei0.64
0.76
Nt5dc2STRStriatum1.01
0.99
Nt5dc2STRdStriatum dorsal region0.91
0.92
Nt5dc2STRvStriatum ventral region0.77
0.53
Nt5dc2THThalamus0.51
0.72
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00038808 18 353 370 VLYFGDHLYSDLADLMLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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