AutismKB 2.0

Annotation Detail for SKIV2L


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Basic Information Top
Gene Symbol:SKIV2L ( 170A,DDX13,HLP,SKI2,SKI2W,SKIV2 )
Gene Full Name: superkiller viralicidic activity 2-like (S. cerevisiae)
Band: 6p21.33
Quick LinksEntrez ID:6499; OMIM: 600478; Uniprot ID:SKIV2_HUMAN; ENSEMBL ID: ENSG00000204351; HGNC ID: 10898
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor1 / 3436629
chondrosarcoma10 / 82823120
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor12 / 119369100
germ cell tumor17 / 26384564
glioma5 / 10688346
head and neck tumor4 / 13630229
kidney tumor5 / 6895972
leukemia5 / 9584252
liver tumor1 / 9635910
lung tumor8 / 10312777
lymphoma3 / 7175541
non-neoplasia4 / 9725041
normal100 / 336030729
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer6 / 10268058
retinoblastoma9 / 46356194
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites7 / 40015174
bladder1 / 2975733
blood4 / 12347832
bone5 / 7165569
bone marrow2 / 4880140
brain32 / 110098929
cervix5 / 48171103
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus1 / 2020949
eye16 / 21105475
heart1 / 8962611
intestine7 / 23447229
kidney7 / 21177733
larynx0 / 241450 
liver2 / 2077439
lung19 / 33697456
lymph1 / 4427022
lymph node5 / 9161054
mammary gland9 / 15327158
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary3 / 10205129
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate10 / 18934552
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach5 / 9661951
testis10 / 33044230
thymus8 / 8113198
thyroid3 / 4747363
tonsil2 / 16999117
trachea1 / 5241319
umbilical cord0 / 136800 
uterus15 / 23287864
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203727_at
Cell line Expression level Expression bar
721_B_lymphoblasts124.1
Adipocyte46.1
AdrenalCortex77.25
Adrenalgland41.9
Amygdala47.9
Appendix24.55
AtrioventricularNode30.9
BDCA4+_DentriticCells169.85
Bonemarrow48.75
BronchialEpithelialCells46.9
CD105+_Endothelial163.25
CD14+_Monocytes139.6
CD19+_BCells(neg._sel.)79.85
CD33+_Myeloid164.2
CD34+183.5
CD4+_Tcells220
CD56+_NKCells220.6
CD71+_EarlyErythroid120.25
CD8+_Tcells189.15
CardiacMyocytes57.35
Caudatenucleus43
Cerebellum36.4
CerebellumPeduncles52.15
CiliaryGanglion30.5
CingulateCortex52.5
Colorectaladenocarcinoma85.05
DorsalRootGanglion28.5
FetalThyroid47.95
Fetalbrain47
Fetalliver41.55
Fetallung53.85
GlobusPallidus30.65
Heart84.45
Hypothalamus69.1
Kidney35.5
Leukemia_chronicMyelogenousK-56272.6
Leukemia_promyelocytic-HL-6050.45
Leukemialymphoblastic(MOLT-4)62.05
Liver80.65
Lung84
Lymphnode54.85
Lymphoma_burkitts(Daudi)62.05
Lymphoma_burkitts(Raji)293.05
MedullaOblongata35.75
OccipitalLobe42.55
OlfactoryBulb39.5
Ovary26.05
Pancreas37.95
PancreaticIslet63.45
ParietalLobe50.7
Pituitary61
Placenta48.9
Pons42.2
PrefrontalCortex59.7
Prostate133.15
Salivarygland24.35
SkeletalMuscle49.6
Skin36.85
SmoothMuscle56.05
Spinalcord43.85
SubthalamicNucleus45.05
SuperiorCervicalGanglion28.15
TemporalLobe34.3
Testis58.3
TestisGermCell35.35
TestisIntersitial47
TestisLeydigCell36.5
TestisSeminiferousTubule38.1
Thalamus61.6
Thymus46
Thyroid74
Tongue61.6
Tonsil50.95
Trachea36.35
TrigeminalGanglion42.8
Uterus41.5
UterusCorpus32.8
WholeBlood55.9
Wholebrain61.6
colon36.5
pineal_day77.16
pineal_night66.62
retina48.25
small_intestine41.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8514_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.37 ± 0.65
Basal Forebrain4.33 ± 0.45
Basal Part of Pons4.84 ± 0.5
Cerebellar Cortex4.72 ± 0.57
Cerebellar Nuclei4.6 ± 0.44
Claustrum4.04 ± 0.65
Epithalamus4.43 ± 0.61
Frontal Lobe4.88 ± 0.48
Globus Pallidus4.35 ± 0.51
Hypothalamus4.27 ± 0.77
Insula4.97 ± 0.49
Limbic Lobe4.59 ± 0.64
Mesencephalon4.54 ± 0.48
Myelencephalon4.64 ± 0.58
Occipital Lobe4.12 ± 0.6
Parietal Lobe4.56 ± 0.46
Pontine Tegmentum4.51 ± 0.57
Striatum4.23 ± 0.48
Subthalamus4.56 ± 0.16
Temporal Lobe4.8 ± 0.5
Thalamus4.66 ± 0.52
White Matter4.69 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Skiv2lCBCerebellum10.53
10.27
Skiv2lCTXCerebral cortex14.32
9.64
Skiv2lHIPHippocampal region23.49
22.64
Skiv2lHPFHippocampal formation20.45
17.67
Skiv2lHYHypothalamus1.31
1.11
Skiv2lLSXLateral septal complex1.36
0.88
Skiv2lMBMidbrain2.66
2.65
Skiv2lMYMedulla8.39
9.3
Skiv2lOLFOlfactory bulb12.43
8.32
Skiv2lPPons4.93
5.42
Skiv2lPALPallidum3.25
2.65
Skiv2lRHPRetrohippocampal region15.52
10.99
Skiv2lsAMYStriatum-like amygdalar nuclei2.89
1.93
Skiv2lSTRStriatum2.97
2.21
Skiv2lSTRdStriatum dorsal region2.82
2.05
Skiv2lSTRvStriatum ventral region4.28
3.32
Skiv2lTHThalamus5.2
4.33
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003263 14 325 338 HDSVFVAAHTSAGK Peptide Atlas
SKIV2_HUMAN_1031 11 1031 1041 MQIQKEMERLR PRIDE
SKIV2_HUMAN_658 17 658 674 VLFATETFAMGVNMPAR PRIDE
SKIV2_HUMAN_691 13 691 703 DLLPGEYVQMAGR PRIDE
SKIV2_HUMAN_723 9 723 731 VPEMADLHR PRIDE
SKIV2_HUMAN_992 10 992 1001 DMSVVEGGLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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