AutismKB 2.0

Annotation Detail for NDRG4


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Basic Information Top
Gene Symbol:NDRG4 ( DKFZp686I1615,FLJ30586,FLJ42011,KIAA1180,MGC19632,SMAP-8 )
Gene Full Name: NDRG family member 4
Band: 16q21
Quick LinksEntrez ID:65009; OMIM: NA; Uniprot ID:NDRG4_HUMAN; ENSEMBL ID: ENSG00000103034; HGNC ID: 14466
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus188 / 564012333
neonate2 / 3109764
infant5 / 23620211
juvenile13 / 55556233
adult127 / 193912165
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor25 / 26384594
glioma9 / 10688384
head and neck tumor16 / 136302117
kidney tumor53 / 68959768
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia10 / 97250102
normal1445 / 3360307430
ovarian tumor0 / 766820 
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain1366 / 11009891240
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus1 / 2020949
eye28 / 211054132
heart10 / 89626111
intestine3 / 23447212
kidney54 / 211777254
larynx9 / 24145372
liver0 / 2077430 
lung10 / 33697429
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth7 / 67052104
muscle7 / 10771564
nerve11 / 15768697
ovary0 / 1020510 
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate4 / 18934521
salivary gland0 / 201550 
skin0 / 2105740 
spleen7 / 53952129
stomach2 / 9661920
testis57 / 330442172
thymus6 / 8113173
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus7 / 23287830
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209159_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.85
Adipocyte3.8
AdrenalCortex93.05
Adrenalgland74.95
Amygdala829.25
Appendix3.9
AtrioventricularNode2.9
BDCA4+_DentriticCells4.3
Bonemarrow3.75
BronchialEpithelialCells3.75
CD105+_Endothelial3.85
CD14+_Monocytes4.1
CD19+_BCells(neg._sel.)4.1
CD33+_Myeloid5
CD34+4.95
CD4+_Tcells4.25
CD56+_NKCells4.6
CD71+_EarlyErythroid3.55
CD8+_Tcells3.8
CardiacMyocytes4.8
Caudatenucleus462
Cerebellum1066.55
CerebellumPeduncles1310
CiliaryGanglion40.8
CingulateCortex823
Colorectaladenocarcinoma3.95
DorsalRootGanglion93.55
FetalThyroid3.7
Fetalbrain258.3
Fetalliver3.4
Fetallung3.25
GlobusPallidus359.85
Heart466.3
Hypothalamus1134.55
Kidney3.05
Leukemia_chronicMyelogenousK-5623.45
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.1
Liver4.95
Lung16.95
Lymphnode3.4
Lymphoma_burkitts(Daudi)4.9
Lymphoma_burkitts(Raji)5.4
MedullaOblongata617.9
OccipitalLobe823.8
OlfactoryBulb8.9
Ovary2.55
Pancreas3.05
PancreaticIslet27.25
ParietalLobe597.85
Pituitary50.85
Placenta4.05
Pons434.55
PrefrontalCortex1175.2
Prostate4.6
Salivarygland3.05
SkeletalMuscle4.25
Skin2.9
SmoothMuscle4.5
Spinalcord171.5
SubthalamicNucleus570.25
SuperiorCervicalGanglion6.65
TemporalLobe514.85
Testis10.35
TestisGermCell91.35
TestisIntersitial21.8
TestisLeydigCell5.5
TestisSeminiferousTubule38.05
Thalamus1281.25
Thymus3.05
Thyroid4.95
Tongue3.75
Tonsil3.7
Trachea3.2
TrigeminalGanglion14.8
Uterus3.35
UterusCorpus4.45
WholeBlood4.2
Wholebrain926.6
colon3.9
pineal_day938.8
pineal_night1159.36
retina203.475
small_intestine3.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P140748
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.32 ± 0.44
Basal Forebrain13.32 ± 0.23
Basal Part of Pons14.37 ± 0.1
Cerebellar Cortex13.89 ± 0.13
Cerebellar Nuclei14.07 ± 0.39
Claustrum13.52 ± 0.21
Epithalamus12.7 ± 0.53
Frontal Lobe13.91 ± 0.3
Globus Pallidus12.95 ± 0.4
Hypothalamus13.32 ± 0.33
Insula13.86 ± 0.13
Limbic Lobe13.8 ± 0.42
Mesencephalon13.5 ± 0.41
Myelencephalon13.59 ± 0.58
Occipital Lobe13.28 ± 0.54
Parietal Lobe13.74 ± 0.33
Pontine Tegmentum13.55 ± 0.35
Striatum13.1 ± 0.42
Subthalamus14.27 ± 0.02
Temporal Lobe13.77 ± 0.29
Thalamus13.92 ± 0.36
White Matter11.23 ± 0.31
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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