AutismKB 2.0

Annotation Detail for RTN4R


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RTN4R ( NGR,NOGOR )
Gene Full Name: reticulon 4 receptor
Band: 22q11.21
Quick LinksEntrez ID:65078; OMIM: 605566; Uniprot ID:RTN4R_HUMAN; ENSEMBL ID: ENSG00000040608; HGNC ID: 18601
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus17 / 56401230
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal45 / 336030713
ovarian tumor9 / 76682117
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer2 / 10268019
retinoblastoma4 / 4635686
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone2 / 7165527
bone marrow0 / 488010 
brain30 / 110098927
cervix12 / 48171249
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye8 / 21105437
heart0 / 896260 
intestine3 / 23447212
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary10 / 10205197
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach3 / 9661931
testis2 / 3304426
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9902_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.54 ± 0.66
Basal Forebrain12.26 ± 0.24
Basal Part of Pons12.95 ± 0.23
Cerebellar Cortex12.26 ± 0.46
Cerebellar Nuclei12.51 ± 0.5
Claustrum12.13 ± 0.48
Epithalamus12.36 ± 0.43
Frontal Lobe12.66 ± 0.5
Globus Pallidus12.89 ± 0.26
Hypothalamus12.2 ± 0.58
Insula12.49 ± 0.71
Limbic Lobe12.69 ± 0.44
Mesencephalon12.32 ± 0.42
Myelencephalon12.61 ± 0.51
Occipital Lobe12.42 ± 0.43
Parietal Lobe12.47 ± 0.5
Pontine Tegmentum12.41 ± 0.58
Striatum12.76 ± 0.53
Subthalamus12.14 ± 0.41
Temporal Lobe12.63 ± 0.45
Thalamus12.56 ± 0.43
White Matter13.12 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rtn4rCBCerebellum48.72
64.32
Rtn4rCTXCerebral cortex100
100
Rtn4rHIPHippocampal region100
100
Rtn4rHPFHippocampal formation100
100
Rtn4rHYHypothalamus1.8
1.68
Rtn4rLSXLateral septal complex5.82
8
Rtn4rMBMidbrain6.66
6.75
Rtn4rMYMedulla7.61
9.78
Rtn4rOLFOlfactory bulb62.51
76.89
Rtn4rPPons7.25
8.22
Rtn4rPALPallidum2.01
2.06
Rtn4rRHPRetrohippocampal region100
100
Rtn4rsAMYStriatum-like amygdalar nuclei9.6
9.2
Rtn4rSTRStriatum5.24
6.1
Rtn4rSTRdStriatum dorsal region3.78
4.58
Rtn4rSTRvStriatum ventral region6.46
7.25
Rtn4rTHThalamus48.05
49.86
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018