AutismKB 2.0

Annotation Detail for NOL6


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Basic Information Top
Gene Symbol:NOL6 ( FLJ21959,MGC14896,MGC14921,MGC20838,NRAP,UTP22,bA311H10.1 )
Gene Full Name: nucleolar protein family 6 (RNA-associated)
Band: 9p13.3
Quick LinksEntrez ID:65083; OMIM: 611532; Uniprot ID:NOL6_HUMAN; ENSEMBL ID: ENSG00000165271; HGNC ID: 19910
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus34 / 56401260
neonate6 / 31097192
infant1 / 2362042
juvenile5 / 5555689
adult149 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor7 / 34366203
chondrosarcoma1 / 8282312
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor23 / 26384587
glioma7 / 10688365
head and neck tumor37 / 136302271
kidney tumor2 / 6895929
leukemia10 / 95842104
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma9 / 71755125
non-neoplasia1 / 9725010
normal244 / 336030772
ovarian tumor27 / 76682352
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer18 / 102680175
retinoblastoma3 / 4635664
skin tumor9 / 12494972
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites4 / 4001599
bladder2 / 2975767
blood9 / 12347872
bone2 / 7165527
bone marrow2 / 4880140
brain112 / 1100989101
cervix7 / 48171145
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye7 / 21105433
heart3 / 8962633
intestine13 / 23447255
kidney11 / 21177751
larynx5 / 24145207
liver5 / 20774324
lung12 / 33697435
lymph8 / 44270180
lymph node10 / 91610109
mammary gland16 / 153271104
mouth32 / 67052477
muscle13 / 107715120
nerve0 / 157680 
ovary27 / 102051264
pancreas12 / 21481255
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta18 / 28082564
prostate24 / 189345126
salivary gland0 / 201550 
skin14 / 21057466
spleen1 / 5395218
stomach4 / 9661941
testis37 / 330442111
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea11 / 52413209
umbilical cord8 / 13680584
uterus22 / 23287894
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218199_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts120.05
Adipocyte68.25
AdrenalCortex87.1
Adrenalgland80.4
Amygdala49.8
Appendix54.75
AtrioventricularNode67.95
BDCA4+_DentriticCells43
Bonemarrow67.85
BronchialEpithelialCells66.7
CD105+_Endothelial62.35
CD14+_Monocytes42.2
CD19+_BCells(neg._sel.)59.05
CD33+_Myeloid49.8
CD34+51.75
CD4+_Tcells71.25
CD56+_NKCells42.15
CD71+_EarlyErythroid65.85
CD8+_Tcells64.9
CardiacMyocytes75.3
Caudatenucleus48.05
Cerebellum73.2
CerebellumPeduncles94.45
CiliaryGanglion23.15
CingulateCortex100.8
Colorectaladenocarcinoma45.55
DorsalRootGanglion49.35
FetalThyroid76.6
Fetalbrain57.15
Fetalliver58.4
Fetallung50.55
GlobusPallidus78.1
Heart68.9
Hypothalamus61.55
Kidney72.75
Leukemia_chronicMyelogenousK-56295.8
Leukemia_promyelocytic-HL-6055.3
Leukemialymphoblastic(MOLT-4)54.55
Liver74.45
Lung49.55
Lymphnode61.2
Lymphoma_burkitts(Daudi)124.85
Lymphoma_burkitts(Raji)79.55
MedullaOblongata72.5
OccipitalLobe65.7
OlfactoryBulb52.95
Ovary64.2
Pancreas53.9
PancreaticIslet75.3
ParietalLobe94.7
Pituitary86.55
Placenta75.4
Pons94.4
PrefrontalCortex90
Prostate43.2
Salivarygland73.05
SkeletalMuscle124.75
Skin41.6
SmoothMuscle53.05
Spinalcord54.25
SubthalamicNucleus68.85
SuperiorCervicalGanglion97.8
TemporalLobe75.45
Testis70
TestisGermCell41
TestisIntersitial50.45
TestisLeydigCell84.3
TestisSeminiferousTubule64.2
Thalamus71.3
Thymus55.35
Thyroid63.35
Tongue66.75
Tonsil64.35
Trachea57.75
TrigeminalGanglion86
Uterus28.9
UterusCorpus67.75
WholeBlood48.35
Wholebrain43.6
colon30.1
pineal_day117.04
pineal_night122.08
retina97.725
small_intestine30.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P38572
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.54 ± 0.66
Basal Forebrain6.62 ± 0.3
Basal Part of Pons6.44 ± 0.57
Cerebellar Cortex5.75 ± 0.49
Cerebellar Nuclei7.57 ± 0.61
Claustrum6.71 ± 0.91
Epithalamus5.02 ± 1.22
Frontal Lobe6.64 ± 0.79
Globus Pallidus7.55 ± 0.6
Hypothalamus5.98 ± 0.79
Insula6.13 ± 0.75
Limbic Lobe6.51 ± 0.89
Mesencephalon6.78 ± 0.63
Myelencephalon6.72 ± 0.97
Occipital Lobe6.58 ± 0.84
Parietal Lobe6.64 ± 0.83
Pontine Tegmentum6.8 ± 0.83
Striatum7.65 ± 0.83
Subthalamus6.81 ± 0.51
Temporal Lobe6.35 ± 0.84
Thalamus7.31 ± 0.63
White Matter5.35 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nol6CBCerebellum32.23
43.04
Nol6CTXCerebral cortex100
93.08
Nol6HIPHippocampal region72.71
100
Nol6HPFHippocampal formation80.45
100
Nol6HYHypothalamus62
55.56
Nol6LSXLateral septal complex70.17
59.15
Nol6MBMidbrain69.14
68.35
Nol6MYMedulla65.3
77.56
Nol6OLFOlfactory bulb76.8
69.35
Nol6PPons71.08
85.12
Nol6PALPallidum67.91
67.79
Nol6RHPRetrohippocampal region95.78
86.01
Nol6sAMYStriatum-like amygdalar nuclei71.34
61.38
Nol6STRStriatum82.92
66.87
Nol6STRdStriatum dorsal region82.99
66.29
Nol6STRvStriatum ventral region95.09
74.95
Nol6THThalamus83.09
79.4
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NOL6_HUMAN_2 10 2 11 GPAPAGEQLR PRIDE
NOL6_HUMAN_942 14 942 955 AQLPVMVIVTPQDR PRIDE
PAp00004679 14 765 778 LAELLTQQHGLQCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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