Annotation Detail for WNK2
Basic Information Top
| Gene Symbol: | WNK2 ( KIAA1760,NY-CO-43,P/OKcl.13,PRKWNK2,SDCCAG43 ) |
|---|---|
| Gene Full Name: | WNK lysine deficient protein kinase 2 |
| Band: | 9q22.31 |
| Quick Links | Entrez ID:65268; OMIM: 606249; Uniprot ID:WNK2_HUMAN; ENSEMBL ID: ENSG00000165238; HGNC ID: 14542 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.654856
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 12 / 564012 | 21 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 50 / 1939121 | 25 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 7 / 114246 | 61 |  |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 5 / 71755 | 69 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 97 / 3360307 | 28 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 46 / 1100989 | 41 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 11 / 211054 | 52 | |
| heart | 3 / 89626 | 33 | |
| intestine | 16 / 234472 | 68 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 1 / 24145 | 41 | |
| liver | 0 / 207743 | 0 | |
| lung | 4 / 336974 | 11 | |
| lymph | 4 / 44270 | 90 | |
| lymph node | 4 / 91610 | 43 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 7 / 214812 | 32 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 8 / 330442 | 24 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 6 / 52413 | 114 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 8 / 232878 | 34 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_24_P117845
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.34 ± 0.71 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.71 ± 0.3 | |
| Basal Part of Pons | 5.12 ± 0.43 | |
| Cerebellar Cortex | 4.97 ± 0.62 | |
| Cerebellar Nuclei | 4.42 ± 0.52 | |
| Claustrum | 5.8 ± 0.95 | |
| Epithalamus | 4.44 ± 0.35 | |
| Frontal Lobe | 4.73 ± 0.74 | |
| Globus Pallidus | 4.57 ± 0.56 | |
| Hypothalamus | 4.06 ± 0.51 | |
| Insula | 4.7 ± 0.53 | |
| Limbic Lobe | 5.25 ± 0.74 | |
| Mesencephalon | 4.93 ± 0.61 | |
| Myelencephalon | 4.91 ± 0.71 | |
| Occipital Lobe | 5.39 ± 0.71 | |
| Parietal Lobe | 5.04 ± 0.68 | |
| Pontine Tegmentum | 4.71 ± 0.7 | |
| Striatum | 5.04 ± 0.58 | |
| Subthalamus | 4.12 ± 0.46 | |
| Temporal Lobe | 4.84 ± 0.66 | |
| Thalamus | 5.12 ± 0.56 | |
| White Matter | 4.22 ± 0.54 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Wnk2 | CB | Cerebellum | 100 | |
| 100 | | |||
| Wnk2 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Wnk2 | HIP | Hippocampal region | 71.72 | |
| 100 | | |||
| Wnk2 | HPF | Hippocampal formation | 89.52 | |
| 100 | | |||
| Wnk2 | HY | Hypothalamus | 60.81 | |
| 50.97 | | |||
| Wnk2 | LSX | Lateral septal complex | 62.91 | |
| 49.53 | | |||
| Wnk2 | MB | Midbrain | 83.91 | |
| 81.94 | | |||
| Wnk2 | MY | Medulla | 65.34 | |
| 77.89 | | |||
| Wnk2 | OLF | Olfactory bulb | 99.06 | |
| 100 | | |||
| Wnk2 | P | Pons | 58.95 | |
| 65.44 | | |||
| Wnk2 | PAL | Pallidum | 60.29 | |
| 56.5 | | |||
| Wnk2 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Wnk2 | sAMY | Striatum-like amygdalar nuclei | 82.15 | |
| 66.06 | | |||
| Wnk2 | STR | Striatum | 60.65 | |
| 49.22 | | |||
| Wnk2 | STRd | Striatum dorsal region | 54.37 | |
| 44.77 | | |||
| Wnk2 | STRv | Striatum ventral region | 76.37 | |
| 59.21 | | |||
| Wnk2 | TH | Thalamus | 100 | |
| 100 | |