AutismKB 2.0

Annotation Detail for SLC9A1


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Basic Information Top
Gene Symbol:SLC9A1 ( APNH,FLJ42224,NHE1 )
Gene Full Name: solute carrier family 9 (sodium/hydrogen exchanger), member 1
Band: 1p36.11
Quick LinksEntrez ID:6548; OMIM: 107310; Uniprot ID:SL9A1_HUMAN; ENSEMBL ID: ENSG00000090020; HGNC ID: 11071
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst2 / 6231932
fetus8 / 56401214
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult99 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor13 / 114246113
esophageal tumor2 / 17290115
gastrointestinal tumor3 / 11936925
germ cell tumor14 / 26384553
glioma5 / 10688346
head and neck tumor13 / 13630295
kidney tumor4 / 6895958
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal125 / 336030737
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain43 / 110098939
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus2 / 2020998
eye8 / 21105437
heart0 / 896260 
intestine16 / 23447268
kidney5 / 21177723
larynx0 / 241450 
liver1 / 2077434
lung4 / 33697411
lymph1 / 4427022
lymph node0 / 916100 
mammary gland9 / 15327158
mouth7 / 67052104
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas5 / 21481223
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta30 / 280825106
prostate4 / 18934521
salivary gland2 / 2015599
skin7 / 21057433
spleen3 / 5395255
stomach3 / 9661931
testis16 / 33044248
thymus3 / 8113136
thyroid7 / 47473147
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord2 / 13680146
uterus6 / 23287825
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209453_at
Cell line Expression level Expression bar
721_B_lymphoblasts13
Adipocyte11.25
AdrenalCortex9
Adrenalgland9.8
Amygdala12.25
Appendix9.65
AtrioventricularNode7.25
BDCA4+_DentriticCells9.85
Bonemarrow10.65
BronchialEpithelialCells14.4
CD105+_Endothelial8
CD14+_Monocytes9.55
CD19+_BCells(neg._sel.)9.15
CD33+_Myeloid9.65
CD34+10.8
CD4+_Tcells10.75
CD56+_NKCells15.55
CD71+_EarlyErythroid4.2
CD8+_Tcells8.85
CardiacMyocytes12.2
Caudatenucleus21.1
Cerebellum10.55
CerebellumPeduncles12.45
CiliaryGanglion5.9
CingulateCortex14.7
Colorectaladenocarcinoma16.8
DorsalRootGanglion6.4
FetalThyroid9.6
Fetalbrain9
Fetalliver7.25
Fetallung8.25
GlobusPallidus7.2
Heart17.5
Hypothalamus10.8
Kidney8
Leukemia_chronicMyelogenousK-5628.1
Leukemia_promyelocytic-HL-6010.65
Leukemialymphoblastic(MOLT-4)9.5
Liver11.05
Lung29.75
Lymphnode9.7
Lymphoma_burkitts(Daudi)11.6
Lymphoma_burkitts(Raji)34.55
MedullaOblongata11.8
OccipitalLobe8.65
OlfactoryBulb8.45
Ovary6.95
Pancreas8.85
PancreaticIslet10.4
ParietalLobe13.4
Pituitary11.25
Placenta145.7
Pons12.6
PrefrontalCortex15.8
Prostate24.35
Salivarygland17.05
SkeletalMuscle12.65
Skin5.25
SmoothMuscle12.55
Spinalcord10.45
SubthalamicNucleus8.8
SuperiorCervicalGanglion12.45
TemporalLobe9.2
Testis8.2
TestisGermCell7.7
TestisIntersitial8
TestisLeydigCell8.65
TestisSeminiferousTubule7.3
Thalamus13.2
Thymus7.65
Thyroid15.75
Tongue9.6
Tonsil9.5
Trachea15.55
TrigeminalGanglion9.85
Uterus7.75
UterusCorpus10.25
WholeBlood16.3
Wholebrain15.75
colon12.8
pineal_day15.04
pineal_night12.76
retina18.8
small_intestine10.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14306_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.13 ± 1.05
Basal Forebrain1.58 ± 0.22
Basal Part of Pons1.88 ± 1.19
Cerebellar Cortex1.61 ± 0.76
Cerebellar Nuclei2.1 ± 0.74
Claustrum2.35 ± 0.79
Epithalamus1.33 ± 0.8
Frontal Lobe1.57 ± 0.82
Globus Pallidus2.02 ± 0.79
Hypothalamus1.62 ± 0.75
Insula1.63 ± 0.82
Limbic Lobe1.79 ± 0.79
Mesencephalon1.83 ± 0.76
Myelencephalon1.76 ± 0.71
Occipital Lobe1.88 ± 0.69
Parietal Lobe1.66 ± 0.67
Pontine Tegmentum1.73 ± 0.68
Striatum2.07 ± 0.86
Subthalamus1.77 ± 0.67
Temporal Lobe1.65 ± 0.74
Thalamus1.77 ± 0.69
White Matter1.66 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slc9a1CBCerebellum44.48
60.6
Slc9a1CTXCerebral cortex100
95.54
Slc9a1HIPHippocampal region70.53
100
Slc9a1HPFHippocampal formation81.7
98.15
Slc9a1HYHypothalamus72.04
66.83
Slc9a1LSXLateral septal complex66.37
54.39
Slc9a1MBMidbrain70.02
75.26
Slc9a1MYMedulla77.81
100
Slc9a1OLFOlfactory bulb100
100
Slc9a1PPons75.64
99.76
Slc9a1PALPallidum71.38
76.71
Slc9a1RHPRetrohippocampal region99.04
95.94
Slc9a1sAMYStriatum-like amygdalar nuclei89.4
86.27
Slc9a1STRStriatum100
98.03
Slc9a1STRdStriatum dorsal region100
100
Slc9a1STRvStriatum ventral region100
96.9
Slc9a1THThalamus92.65
97.76
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064515 20 794 813 CLSDPGPHPEPGEGEPFFPK Peptide Atlas
SL9A1_HUMAN_39 9 39 47 LSPTASTIR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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