AutismKB 2.0

Annotation Detail for SLC9A5


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Basic Information Top
Gene Symbol:SLC9A5 ( NHE5 )
Gene Full Name: solute carrier family 9 (sodium/hydrogen exchanger), member 5
Band: 16q22.1
Quick LinksEntrez ID:6553; OMIM: 600477; Uniprot ID:SL9A5_HUMAN; ENSEMBL ID: ENSG00000135740; HGNC ID: 11078
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult17 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal27 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung4 / 33697411
lymph0 / 442700 
lymph node1 / 9161010
mammary gland6 / 15327139
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220650_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.85
Adipocyte4.45
AdrenalCortex4.6
Adrenalgland3.8
Amygdala4.95
Appendix4.6
AtrioventricularNode4.35
BDCA4+_DentriticCells7.25
Bonemarrow4.45
BronchialEpithelialCells4.45
CD105+_Endothelial5
CD14+_Monocytes4.65
CD19+_BCells(neg._sel.)4.9
CD33+_Myeloid5.75
CD34+5.65
CD4+_Tcells4.9
CD56+_NKCells5.75
CD71+_EarlyErythroid4.4
CD8+_Tcells4.45
CardiacMyocytes5.65
Caudatenucleus4.8
Cerebellum4.25
CerebellumPeduncles5.95
CiliaryGanglion4.15
CingulateCortex4.65
Colorectaladenocarcinoma4.6
DorsalRootGanglion4.45
FetalThyroid4.4
Fetalbrain4.7
Fetalliver3.85
Fetallung3.65
GlobusPallidus3.3
Heart7.05
Hypothalamus4.8
Kidney3.6
Leukemia_chronicMyelogenousK-5624.05
Leukemia_promyelocytic-HL-604
Leukemialymphoblastic(MOLT-4)3.5
Liver6.55
Lung4.9
Lymphnode3.7
Lymphoma_burkitts(Daudi)5.8
Lymphoma_burkitts(Raji)6.6
MedullaOblongata4.05
OccipitalLobe4.35
OlfactoryBulb3.55
Ovary3
Pancreas3.75
PancreaticIslet4.8
ParietalLobe4.8
Pituitary5.15
Placenta4.5
Pons4.55
PrefrontalCortex10.55
Prostate5.25
Salivarygland3.6
SkeletalMuscle5.4
Skin4
SmoothMuscle5
Spinalcord4.8
SubthalamicNucleus4.1
SuperiorCervicalGanglion5.2
TemporalLobe4.4
Testis4
TestisGermCell3.7
TestisIntersitial4
TestisLeydigCell4.45
TestisSeminiferousTubule3.85
Thalamus5.15
Thymus3.5
Thyroid5.7
Tongue4.5
Tonsil4.3
Trachea3.7
TrigeminalGanglion4.8
Uterus3.65
UterusCorpus4
WholeBlood4.8
Wholebrain4.6
colon4.5
pineal_day5.72
pineal_night5.58
retina5.425
small_intestine4.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5353_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.57 ± 1.03
Basal Forebrain2.17 ± 0.35
Basal Part of Pons1.98 ± 0.46
Cerebellar Cortex3.22 ± 0.43
Cerebellar Nuclei2.5 ± 0.54
Claustrum2.78 ± 0.75
Epithalamus2.12 ± 0.84
Frontal Lobe2.31 ± 0.86
Globus Pallidus1.83 ± 0.6
Hypothalamus2.31 ± 0.68
Insula2.51 ± 0.96
Limbic Lobe2.31 ± 0.95
Mesencephalon2.52 ± 0.85
Myelencephalon2.42 ± 0.72
Occipital Lobe2.38 ± 0.83
Parietal Lobe2.55 ± 0.78
Pontine Tegmentum2.48 ± 0.75
Striatum2.4 ± 0.96
Subthalamus2.39 ± 0.77
Temporal Lobe2.36 ± 0.82
Thalamus2.29 ± 0.69
White Matter1.77 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slc9a5CBCerebellum61.92
99.7
Slc9a5CTXCerebral cortex21
16.81
Slc9a5HIPHippocampal region3.91
4.45
Slc9a5HPFHippocampal formation3.2
3.54
Slc9a5HYHypothalamus3.25
3.49
Slc9a5LSXLateral septal complex6.36
5.44
Slc9a5MBMidbrain4.24
5.61
Slc9a5MYMedulla7.27
8.37
Slc9a5OLFOlfactory bulb19.1
18.94
Slc9a5PPons4.14
4.6
Slc9a5PALPallidum1.76
1.77
Slc9a5RHPRetrohippocampal region2.14
2.35
Slc9a5sAMYStriatum-like amygdalar nuclei5.64
3.72
Slc9a5STRStriatum5.96
4.27
Slc9a5STRdStriatum dorsal region5.32
3.89
Slc9a5STRvStriatum ventral region8.09
5.38
Slc9a5THThalamus1.03
1.45
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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