AutismKB 2.0

Annotation Detail for SLC10A2


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Basic Information Top
Gene Symbol:SLC10A2 ( ASBT,IBAT,ISBT,NTCP2,PBAM )
Gene Full Name: solute carrier family 10 (sodium/bile acid cotransporter family), member 2
Band: 13q33.1
Quick LinksEntrez ID:6555; OMIM: 601295; Uniprot ID:NTCP2_HUMAN; ENSEMBL ID: ENSG00000125255; HGNC ID: 10906
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult0 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal14 / 33603074
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine2 / 2344728
kidney13 / 21177761
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207095_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.95
Adipocyte6.3
AdrenalCortex8.05
Adrenalgland5.8
Amygdala6.4
Appendix7.8
AtrioventricularNode5.8
BDCA4+_DentriticCells6.25
Bonemarrow6.55
BronchialEpithelialCells6.85
CD105+_Endothelial6.4
CD14+_Monocytes6.25
CD19+_BCells(neg._sel.)6.5
CD33+_Myeloid7.7
CD34+7.3
CD4+_Tcells6.8
CD56+_NKCells6.95
CD71+_EarlyErythroid6.4
CD8+_Tcells5.65
CardiacMyocytes8
Caudatenucleus5.8
Cerebellum5.35
CerebellumPeduncles7.75
CiliaryGanglion5.15
CingulateCortex6.8
Colorectaladenocarcinoma6.5
DorsalRootGanglion5.6
FetalThyroid6.3
Fetalbrain6.15
Fetalliver5.75
Fetallung5.4
GlobusPallidus5.05
Heart9.85
Hypothalamus6.8
Kidney5.9
Leukemia_chronicMyelogenousK-5627.55
Leukemia_promyelocytic-HL-605.65
Leukemialymphoblastic(MOLT-4)4.9
Liver9.6
Lung7
Lymphnode5.25
Lymphoma_burkitts(Daudi)8.35
Lymphoma_burkitts(Raji)9.65
MedullaOblongata5.9
OccipitalLobe5.75
OlfactoryBulb5.1
Ovary5.35
Pancreas5.3
PancreaticIslet7.45
ParietalLobe7.35
Pituitary7.5
Placenta5.95
Pons6.4
PrefrontalCortex7.7
Prostate7.55
Salivarygland5.6
SkeletalMuscle10.65
Skin5.55
SmoothMuscle6.55
Spinalcord6.85
SubthalamicNucleus6.7
SuperiorCervicalGanglion9.6
TemporalLobe8.05
Testis5.5
TestisGermCell5.4
TestisIntersitial5.55
TestisLeydigCell6.6
TestisSeminiferousTubule5.55
Thalamus6.7
Thymus4.55
Thyroid7.7
Tongue7.65
Tonsil6.35
Trachea5.4
TrigeminalGanglion9
Uterus5.1
UterusCorpus12.6
WholeBlood6.9
Wholebrain5
colon6.55
pineal_day7.72
pineal_night7.74
retina7.65
small_intestine28.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12455_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.32 ± 1.16
Basal Forebrain1.77 ± 0.22
Basal Part of Pons1.53 ± 0.42
Cerebellar Cortex1.94 ± 0.82
Cerebellar Nuclei2.31 ± 0.8
Claustrum2.75 ± 0.86
Epithalamus1.48 ± 0.82
Frontal Lobe1.85 ± 0.98
Globus Pallidus2.26 ± 0.55
Hypothalamus1.9 ± 0.65
Insula1.62 ± 0.45
Limbic Lobe1.9 ± 0.78
Mesencephalon2.06 ± 0.78
Myelencephalon1.96 ± 0.73
Occipital Lobe1.88 ± 0.42
Parietal Lobe1.87 ± 0.79
Pontine Tegmentum1.93 ± 0.74
Striatum1.99 ± 0.69
Subthalamus2 ± 0.72
Temporal Lobe1.75 ± 0.66
Thalamus1.9 ± 0.75
White Matter2.22 ± 0.29
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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