AutismKB 2.0

Annotation Detail for SLC16A2


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Basic Information Top
Gene Symbol:SLC16A2 ( AHDS,DXS128,DXS128E,MCT 7,MCT 8,MCT7,MCT8,MRX22,XPCT )
Gene Full Name: solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
Band: Xq13.2
Quick LinksEntrez ID:6567; OMIM: 300095; Uniprot ID:MOT8_HUMAN; ENSEMBL ID: ENSG00000147100; HGNC ID: 10923
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma11 / 106883102
head and neck tumor3 / 13630222
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor6 / 9635962
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal89 / 336030726
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone6 / 7165583
bone marrow0 / 488010 
brain26 / 110098923
cervix0 / 481710 
connective tissue3 / 14925520
ear2 / 16212123
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye4 / 21105418
heart6 / 8962666
intestine0 / 2344720 
kidney17 / 21177780
larynx0 / 241450 
liver6 / 20774328
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth3 / 6705244
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta4 / 28082514
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204462_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.4
Adipocyte5.35
AdrenalCortex3.65
Adrenalgland5.45
Amygdala4.3
Appendix3.6
AtrioventricularNode2.6
BDCA4+_DentriticCells3.85
Bonemarrow3.5
BronchialEpithelialCells3.55
CD105+_Endothelial3.6
CD14+_Monocytes3.75
CD19+_BCells(neg._sel.)3.8
CD33+_Myeloid4.5
CD34+4.6
CD4+_Tcells3.8
CD56+_NKCells4.2
CD71+_EarlyErythroid3.25
CD8+_Tcells3.4
CardiacMyocytes4.45
Caudatenucleus3.45
Cerebellum3.65
CerebellumPeduncles4.15
CiliaryGanglion2.45
CingulateCortex3.6
Colorectaladenocarcinoma3.5
DorsalRootGanglion2.65
FetalThyroid3.45
Fetalbrain6.55
Fetalliver3.05
Fetallung3.1
GlobusPallidus2.6
Heart4.45
Hypothalamus3.9
Kidney3.25
Leukemia_chronicMyelogenousK-5623.15
Leukemia_promyelocytic-HL-603.1
Leukemialymphoblastic(MOLT-4)2.9
Liver6.2
Lung3.95
Lymphnode3.05
Lymphoma_burkitts(Daudi)4.5
Lymphoma_burkitts(Raji)4.9
MedullaOblongata3.25
OccipitalLobe3.2
OlfactoryBulb2.85
Ovary2.3
Pancreas2.8
PancreaticIslet3.8
ParietalLobe3.7
Pituitary6.05
Placenta3.75
Pons3.35
PrefrontalCortex4.65
Prostate4.2
Salivarygland2.8
SkeletalMuscle5.3
Skin2.65
SmoothMuscle5
Spinalcord4.25
SubthalamicNucleus3.2
SuperiorCervicalGanglion4.25
TemporalLobe3.55
Testis3.1
TestisGermCell3
TestisIntersitial2.95
TestisLeydigCell3.45
TestisSeminiferousTubule3.05
Thalamus3.55
Thymus2.85
Thyroid4.8
Tongue3.45
Tonsil3.4
Trachea3
TrigeminalGanglion3.45
Uterus3.05
UterusCorpus3.15
WholeBlood3.9
Wholebrain3.1
colon3.55
pineal_day4.46
pineal_night4.36
retina4.575
small_intestine3.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14599_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.86 ± 0.8
Basal Forebrain2.22 ± 0.25
Basal Part of Pons2.28 ± 0.36
Cerebellar Cortex2.45 ± 0.88
Cerebellar Nuclei2.73 ± 0.73
Claustrum3.1 ± 0.97
Epithalamus2.18 ± 0.82
Frontal Lobe2.34 ± 0.77
Globus Pallidus2.74 ± 0.49
Hypothalamus2.46 ± 0.81
Insula2.29 ± 0.69
Limbic Lobe2.79 ± 0.67
Mesencephalon2.55 ± 0.71
Myelencephalon2.54 ± 0.75
Occipital Lobe2.41 ± 0.77
Parietal Lobe2.56 ± 0.8
Pontine Tegmentum2.47 ± 0.55
Striatum2.65 ± 0.69
Subthalamus2.71 ± 0.83
Temporal Lobe2.55 ± 0.75
Thalamus2.29 ± 0.71
White Matter2.45 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slc16a2CBCerebellum11.2
14.38
Slc16a2CTXCerebral cortex38.45
32.27
Slc16a2HIPHippocampal region39.47
61.85
Slc16a2HPFHippocampal formation42.51
54.27
Slc16a2HYHypothalamus2.92
3.43
Slc16a2LSXLateral septal complex28.47
57.97
Slc16a2MBMidbrain3.72
3.67
Slc16a2MYMedulla17.78
24.78
Slc16a2OLFOlfactory bulb55.62
49.96
Slc16a2PPons5.3
5.34
Slc16a2PALPallidum6.02
5.21
Slc16a2RHPRetrohippocampal region46.6
45.77
Slc16a2sAMYStriatum-like amygdalar nuclei14.58
11.01
Slc16a2STRStriatum15.28
13.32
Slc16a2STRdStriatum dorsal region10.09
9.49
Slc16a2STRvStriatum ventral region30.85
21.74
Slc16a2THThalamus8.51
11.34
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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