Annotation Detail for SLC19A1
Basic Information Top
| Gene Symbol: | SLC19A1 ( CHMD,FOLT,IFC1,REFC,RFC1 ) |
|---|---|
| Gene Full Name: | solute carrier family 19 (folate transporter), member 1 |
| Band: | 21q22.3 |
| Quick Links | Entrez ID:6573; OMIM: 600424; Uniprot ID:S19A1_HUMAN; ENSEMBL ID: ENSG00000173638; HGNC ID: 10937 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.84190
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 8 / 70761 | 113 |  |
| blastocyst | 5 / 62319 | 80 | |
| fetus | 43 / 564012 | 76 | |
| neonate | 3 / 31097 | 96 | |
| infant | 3 / 23620 | 127 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 110 / 1939121 | 56 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 5 / 94178 | 53 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 2 / 82823 | 24 |  |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 9 / 263845 | 34 | |
| glioma | 11 / 106883 | 102 | |
| head and neck tumor | 6 / 136302 | 44 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 6 / 95842 | 62 | |
| liver tumor | 8 / 96359 | 83 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 184 / 3360307 | 54 | |
| ovarian tumor | 6 / 76682 | 78 | |
| pancreatic tumor | 10 / 104616 | 95 | |
| primitive neuroectodermal tumor of the CNS | 24 / 125680 | 190 | |
| prostate cancer | 11 / 102680 | 107 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 2 / 13106 | 152 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 8 / 123478 | 64 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 8 / 48801 | 163 | |
| brain | 61 / 1100989 | 55 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 17 / 215722 | 78 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 12 / 211054 | 56 | |
| heart | 6 / 89626 | 66 | |
| intestine | 14 / 234472 | 59 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 0 / 24145 | 0 | |
| liver | 10 / 207743 | 48 | |
| lung | 16 / 336974 | 47 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 10 / 91610 | 109 | |
| mammary gland | 12 / 153271 | 78 | |
| mouth | 4 / 67052 | 59 | |
| muscle | 1 / 107715 | 9 |  |
| nerve | 1 / 15768 | 63 | |
| ovary | 7 / 102051 | 68 | |
| pancreas | 10 / 214812 | 46 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 22 / 280825 | 78 | |
| prostate | 15 / 189345 | 79 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 8 / 210574 | 37 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 2 / 96619 | 20 | |
| testis | 1 / 330442 | 3 | |
| thymus | 6 / 81131 | 73 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 3 / 51780 | 57 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 209776_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 10.1 | |
| Adipocyte | 4.8 | |
| AdrenalCortex | 5.4 | |
| Adrenalgland | 4.15 | |
| Amygdala | 5 | |
| Appendix | 4.95 | |
| AtrioventricularNode | 3.9 | |
| BDCA4+_DentriticCells | 5.15 | |
| Bonemarrow | 4.9 | |
| BronchialEpithelialCells | 4.75 | |
| CD105+_Endothelial | 4.85 | |
| CD14+_Monocytes | 5.2 | |
| CD19+_BCells(neg._sel.) | 5.2 | |
| CD33+_Myeloid | 6.2 | |
| CD34+ | 7.25 | |
| CD4+_Tcells | 5.25 | |
| CD56+_NKCells | 5.75 | |
| CD71+_EarlyErythroid | 4.6 | |
| CD8+_Tcells | 4.65 | |
| CardiacMyocytes | 6.8 | |
| Caudatenucleus | 4.35 | |
| Cerebellum | 3.95 | |
| CerebellumPeduncles | 5.55 | |
| CiliaryGanglion | 3.55 | |
| CingulateCortex | 5 | |
| Colorectaladenocarcinoma | 4.9 | |
| DorsalRootGanglion | 3.85 | |
| FetalThyroid | 4.7 | |
| Fetalbrain | 4.75 | |
| Fetalliver | 4.25 | |
| Fetallung | 3.8 | |
| GlobusPallidus | 3.6 | |
| Heart | 6.6 | |
| Hypothalamus | 5.15 | |
| Kidney | 4 | |
| Leukemia_chronicMyelogenousK-562 | 4.35 | |
| Leukemia_promyelocytic-HL-60 | 4.25 | |
| Leukemialymphoblastic(MOLT-4) | 3.85 | |
| Liver | 6.8 | |
| Lung | 5.3 | |
| Lymphnode | 4.05 | |
| Lymphoma_burkitts(Daudi) | 6.2 | |
| Lymphoma_burkitts(Raji) | 7.1 | |
| MedullaOblongata | 4.4 | |
| OccipitalLobe | 4.35 | |
| OlfactoryBulb | 3.8 | |
| Ovary | 3.35 | |
| Pancreas | 3.95 | |
| PancreaticIslet | 5.15 | |
| ParietalLobe | 5.2 | |
| Pituitary | 5.6 | |
| Placenta | 5 | |
| Pons | 4.6 | |
| PrefrontalCortex | 5.9 | |
| Prostate | 5.6 | |
| Salivarygland | 3.9 | |
| SkeletalMuscle | 5.8 | |
| Skin | 3.9 | |
| SmoothMuscle | 5.45 | |
| Spinalcord | 5.15 | |
| SubthalamicNucleus | 4.4 | |
| SuperiorCervicalGanglion | 5.95 | |
| TemporalLobe | 4.4 | |
| Testis | 4.1 | |
| TestisGermCell | 3.9 | |
| TestisIntersitial | 4.05 | |
| TestisLeydigCell | 4.8 | |
| TestisSeminiferousTubule | 4.1 | |
| Thalamus | 4.95 | |
| Thymus | 3.75 | |
| Thyroid | 5.95 | |
| Tongue | 4.8 | |
| Tonsil | 4.7 | |
| Trachea | 4.05 | |
| TrigeminalGanglion | 5.05 | |
| Uterus | 3.95 | |
| UterusCorpus | 4.4 | |
| WholeBlood | 7.85 | |
| Wholebrain | 4 | |
| colon | 4.85 | |
| pineal_day | 5.96 | |
| pineal_night | 5.9 | |
| retina | 5.85 | |
| small_intestine | 4.65 | |
- Probe name: CUST_15736_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.77 ± 0.71 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.2 ± 0.44 | |
| Basal Part of Pons | 3.32 ± 0.45 | |
| Cerebellar Cortex | 3.55 ± 0.64 | |
| Cerebellar Nuclei | 3.73 ± 0.5 | |
| Claustrum | 3.84 ± 0.88 | |
| Epithalamus | 3.17 ± 0.77 | |
| Frontal Lobe | 3.63 ± 0.67 | |
| Globus Pallidus | 4.09 ± 0.53 | |
| Hypothalamus | 3.4 ± 0.56 | |
| Insula | 3.67 ± 0.24 | |
| Limbic Lobe | 3.47 ± 0.61 | |
| Mesencephalon | 3.82 ± 0.67 | |
| Myelencephalon | 3.61 ± 0.62 | |
| Occipital Lobe | 3.64 ± 0.5 | |
| Parietal Lobe | 3.6 ± 0.49 | |
| Pontine Tegmentum | 3.62 ± 0.59 | |
| Striatum | 3.95 ± 0.58 | |
| Subthalamus | 3.08 ± 0.63 | |
| Temporal Lobe | 3.5 ± 0.56 | |
| Thalamus | 3.82 ± 0.56 | |
| White Matter | 3.27 ± 0.38 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Slc19a1 | CB | Cerebellum | 92.57 | |
| 69.85 | | |||
| Slc19a1 | CTX | Cerebral cortex | 77.73 | |
| 48.82 | | |||
| Slc19a1 | HIP | Hippocampal region | 81.81 | |
| 62.42 | | |||
| Slc19a1 | HPF | Hippocampal formation | 86.54 | |
| 65.54 | | |||
| Slc19a1 | HY | Hypothalamus | 49.41 | |
| 34.13 | | |||
| Slc19a1 | LSX | Lateral septal complex | 49.88 | |
| 32.48 | | |||
| Slc19a1 | MB | Midbrain | 52.64 | |
| 40.16 | | |||
| Slc19a1 | MY | Medulla | 66.27 | |
| 60.2 | | |||
| Slc19a1 | OLF | Olfactory bulb | 92.27 | |
| 55.75 | | |||
| Slc19a1 | P | Pons | 62.81 | |
| 56.52 | | |||
| Slc19a1 | PAL | Pallidum | 46.19 | |
| 34.27 | | |||
| Slc19a1 | RHP | Retrohippocampal region | 92.59 | |
| 69.02 | | |||
| Slc19a1 | sAMY | Striatum-like amygdalar nuclei | 62.53 | |
| 41.92 | | |||
| Slc19a1 | STR | Striatum | 55.83 | |
| 35.77 | | |||
| Slc19a1 | STRd | Striatum dorsal region | 52.24 | |
| 34.42 | | |||
| Slc19a1 | STRv | Striatum ventral region | 69.7 | |
| 38.67 | | |||
| Slc19a1 | TH | Thalamus | 54.8 | |
| 39.91 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00043218 | 25 | 304 | 328 | VYNGAADAASTLLGAITSFAAGFVK | Peptide Atlas |