AutismKB 2.0

Annotation Detail for SLCO2A1


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Basic Information Top
Gene Symbol:SLCO2A1 ( OATP2A1,PGT,SLC21A2 )
Gene Full Name: solute carrier organic anion transporter family, member 2A1
Band: 3q22.1-q22.2
Quick LinksEntrez ID:6578; OMIM: 601460; Uniprot ID:SO2A1_HUMAN; ENSEMBL ID: ENSG00000174640; HGNC ID: 10955
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal142 / 336030742
ovarian tumor0 / 766820 
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain10 / 11009899
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye5 / 21105423
heart4 / 8962644
intestine9 / 23447238
kidney22 / 211777103
larynx0 / 241450 
liver2 / 2077439
lung18 / 33697453
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas37 / 214812172
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta18 / 28082564
prostate17 / 18934589
salivary gland0 / 201550 
skin0 / 2105740 
spleen3 / 5395255
stomach2 / 9661920
testis3 / 3304429
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus23 / 23287898
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204368_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.8
Adipocyte17.3
AdrenalCortex39.2
Adrenalgland100.4
Amygdala16.05
Appendix18.5
AtrioventricularNode12.35
BDCA4+_DentriticCells13.9
Bonemarrow15.9
BronchialEpithelialCells15.85
CD105+_Endothelial14.15
CD14+_Monocytes15.3
CD19+_BCells(neg._sel.)12.8
CD33+_Myeloid16.05
CD34+15.95
CD4+_Tcells11.7
CD56+_NKCells14.95
CD71+_EarlyErythroid14.3
CD8+_Tcells11
CardiacMyocytes20.3
Caudatenucleus14.55
Cerebellum13.1
CerebellumPeduncles20
CiliaryGanglion18.35
CingulateCortex16.5
Colorectaladenocarcinoma13.85
DorsalRootGanglion24.95
FetalThyroid45.35
Fetalbrain16.25
Fetalliver13.85
Fetallung148.4
GlobusPallidus18.25
Heart22.3
Hypothalamus16.5
Kidney25.55
Leukemia_chronicMyelogenousK-56214.7
Leukemia_promyelocytic-HL-6014
Leukemialymphoblastic(MOLT-4)12.75
Liver20.95
Lung467.95
Lymphnode25.2
Lymphoma_burkitts(Daudi)20.4
Lymphoma_burkitts(Raji)19.45
MedullaOblongata14.65
OccipitalLobe13.95
OlfactoryBulb12.8
Ovary17.7
Pancreas19.05
PancreaticIslet64.15
ParietalLobe21.05
Pituitary23.65
Placenta473.8
Pons18.1
PrefrontalCortex20.05
Prostate30.3
Salivarygland29.35
SkeletalMuscle21.1
Skin18.5
SmoothMuscle18.1
Spinalcord18.35
SubthalamicNucleus14.4
SuperiorCervicalGanglion27.4
TemporalLobe14.5
Testis16.45
TestisGermCell12.8
TestisIntersitial16.05
TestisLeydigCell15.65
TestisSeminiferousTubule13.8
Thalamus16
Thymus36.85
Thyroid145.7
Tongue25.9
Tonsil23.25
Trachea23.65
TrigeminalGanglion16.05
Uterus58.75
UterusCorpus19.95
WholeBlood17.2
Wholebrain13.3
colon22.9
pineal_day14.34
pineal_night16.32
retina138.225
small_intestine41.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11484_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.99 ± 1.02
Basal Forebrain1.43 ± 0.21
Basal Part of Pons1.2 ± 0.31
Cerebellar Cortex1.36 ± 0.74
Cerebellar Nuclei1.77 ± 0.73
Claustrum2.33 ± 0.65
Epithalamus1.32 ± 0.76
Frontal Lobe1.54 ± 0.67
Globus Pallidus1.9 ± 0.39
Hypothalamus1.55 ± 0.74
Insula1.08 ± 0.47
Limbic Lobe1.39 ± 0.62
Mesencephalon1.7 ± 0.68
Myelencephalon1.53 ± 0.66
Occipital Lobe1.39 ± 0.46
Parietal Lobe1.78 ± 0.79
Pontine Tegmentum1.59 ± 0.67
Striatum1.51 ± 0.64
Subthalamus1.93 ± 0.24
Temporal Lobe1.42 ± 0.62
Thalamus1.47 ± 0.6
White Matter1.72 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slco2a1CBCerebellum20.93
22.49
Slco2a1CTXCerebral cortex32.21
21.8
Slco2a1HIPHippocampal region19.93
17.87
Slco2a1HPFHippocampal formation23.56
19.1
Slco2a1HYHypothalamus15.67
10.68
Slco2a1LSXLateral septal complex15.58
10.08
Slco2a1MBMidbrain29.65
23.61
Slco2a1MYMedulla21.87
19.23
Slco2a1OLFOlfactory bulb32.35
24.58
Slco2a1PPons25.81
21.89
Slco2a1PALPallidum20.5
14.95
Slco2a1RHPRetrohippocampal region30.84
21.66
Slco2a1sAMYStriatum-like amygdalar nuclei16.24
10.89
Slco2a1STRStriatum19.65
13.46
Slco2a1STRdStriatum dorsal region23
16.17
Slco2a1STRvStriatum ventral region13.87
9.02
Slco2a1THThalamus34.75
27
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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