Annotation Detail for SLIT3
Basic Information Top
| Gene Symbol: | SLIT3 ( FLJ10764,MEGF5,SLIL2,SLIT1,Slit-3,slit2 ) |
|---|---|
| Gene Full Name: | slit homolog 3 (Drosophila) |
| Band: | 5q34-q35.1 |
| Quick Links | Entrez ID:6586; OMIM: 603745; Uniprot ID:SLIT3_HUMAN; ENSEMBL ID: ENSG00000184347; HGNC ID: 11087 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.604116
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 11 / 70761 | 155 |  |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 21 / 564012 | 37 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 47 / 1939121 | 24 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 6 / 263845 | 22 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 84 / 3360307 | 24 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 18 / 125680 | 143 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 2 / 29757 | 67 | |
| blood | 1 / 123478 | 8 | |
| bone | 5 / 71655 | 69 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 31 / 1100989 | 28 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 12 / 215722 | 55 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 2 / 211054 | 9 | |
| heart | 7 / 89626 | 78 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 4 / 211777 | 18 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 5 / 336974 | 14 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 3 / 210574 | 14 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 7 / 330442 | 21 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 5 / 47473 | 105 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 3 / 232878 | 12 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 203813_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 7.1 | |
| Adipocyte | 108.8 | |
| AdrenalCortex | 8.35 | |
| Adrenalgland | 7.9 | |
| Amygdala | 9.65 | |
| Appendix | 7.25 | |
| AtrioventricularNode | 4.75 | |
| BDCA4+_DentriticCells | 5.95 | |
| Bonemarrow | 6.3 | |
| BronchialEpithelialCells | 5.65 | |
| CD105+_Endothelial | 6.2 | |
| CD14+_Monocytes | 6.3 | |
| CD19+_BCells(neg._sel.) | 6.15 | |
| CD33+_Myeloid | 7 | |
| CD34+ | 6.95 | |
| CD4+_Tcells | 5.4 | |
| CD56+_NKCells | 6.6 | |
| CD71+_EarlyErythroid | 5.65 | |
| CD8+_Tcells | 5.3 | |
| CardiacMyocytes | 8.65 | |
| Caudatenucleus | 5.65 | |
| Cerebellum | 6.55 | |
| CerebellumPeduncles | 19.5 | |
| CiliaryGanglion | 4.8 | |
| CingulateCortex | 6.55 | |
| Colorectaladenocarcinoma | 6.15 | |
| DorsalRootGanglion | 4.95 | |
| FetalThyroid | 18.1 | |
| Fetalbrain | 5.55 | |
| Fetalliver | 5.4 | |
| Fetallung | 7.85 | |
| GlobusPallidus | 4.4 | |
| Heart | 19.05 | |
| Hypothalamus | 6.75 | |
| Kidney | 7.15 | |
| Leukemia_chronicMyelogenousK-562 | 5.85 | |
| Leukemia_promyelocytic-HL-60 | 4.85 | |
| Leukemialymphoblastic(MOLT-4) | 5.35 | |
| Liver | 11.5 | |
| Lung | 68.05 | |
| Lymphnode | 11.3 | |
| Lymphoma_burkitts(Daudi) | 7.85 | |
| Lymphoma_burkitts(Raji) | 9.15 | |
| MedullaOblongata | 6 | |
| OccipitalLobe | 5.55 | |
| OlfactoryBulb | 5.1 | |
| Ovary | 7.7 | |
| Pancreas | 5.1 | |
| PancreaticIslet | 7.25 | |
| ParietalLobe | 7.15 | |
| Pituitary | 10.5 | |
| Placenta | 10.7 | |
| Pons | 6.05 | |
| PrefrontalCortex | 7 | |
| Prostate | 9.8 | |
| Salivarygland | 8.85 | |
| SkeletalMuscle | 12.75 | |
| Skin | 4.8 | |
| SmoothMuscle | 41.3 | |
| Spinalcord | 6.6 | |
| SubthalamicNucleus | 5.85 | |
| SuperiorCervicalGanglion | 7 | |
| TemporalLobe | 5.25 | |
| Testis | 5.2 | |
| TestisGermCell | 6.25 | |
| TestisIntersitial | 7.4 | |
| TestisLeydigCell | 5.95 | |
| TestisSeminiferousTubule | 6.8 | |
| Thalamus | 6.35 | |
| Thymus | 16.05 | |
| Thyroid | 49.4 | |
| Tongue | 9.95 | |
| Tonsil | 5.95 | |
| Trachea | 9 | |
| TrigeminalGanglion | 6.25 | |
| Uterus | 26.85 | |
| UterusCorpus | 9.75 | |
| WholeBlood | 6.25 | |
| Wholebrain | 5.95 | |
| colon | 8.65 | |
| pineal_day | 6.48 | |
| pineal_night | 6.64 | |
| retina | 7.65 | |
| small_intestine | 10.3 | |
- Probe name: CUST_13739_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.68 ± 0.62 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.36 ± 0.42 | |
| Basal Part of Pons | 6.71 ± 0.45 | |
| Cerebellar Cortex | 6.46 ± 0.35 | |
| Cerebellar Nuclei | 5.55 ± 0.5 | |
| Claustrum | 4.73 ± 1.02 | |
| Epithalamus | 5.07 ± 1.1 | |
| Frontal Lobe | 5.91 ± 0.57 | |
| Globus Pallidus | 4.05 ± 0.59 | |
| Hypothalamus | 5.91 ± 0.99 | |
| Insula | 6.13 ± 0.41 | |
| Limbic Lobe | 6.31 ± 0.8 | |
| Mesencephalon | 5.41 ± 0.71 | |
| Myelencephalon | 5.73 ± 0.93 | |
| Occipital Lobe | 5.02 ± 0.84 | |
| Parietal Lobe | 5.43 ± 0.68 | |
| Pontine Tegmentum | 5.48 ± 0.69 | |
| Striatum | 5.47 ± 0.81 | |
| Subthalamus | 4.98 ± 0.06 | |
| Temporal Lobe | 6.18 ± 0.69 | |
| Thalamus | 5.37 ± 0.58 | |
| White Matter | 3.23 ± 0.66 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Slit3 | CB | Cerebellum | 8.94 | |
| 9.92 | | |||
| Slit3 | CTX | Cerebral cortex | 71.5 | |
| 66.68 | | |||
| Slit3 | HIP | Hippocampal region | 99.62 | |
| 100 | | |||
| Slit3 | HPF | Hippocampal formation | 96.5 | |
| 100 | | |||
| Slit3 | HY | Hypothalamus | 6.26 | |
| 5.59 | | |||
| Slit3 | LSX | Lateral septal complex | 16.43 | |
| 14.65 | | |||
| Slit3 | MB | Midbrain | 4.1 | |
| 4.24 | | |||
| Slit3 | MY | Medulla | 13.13 | |
| 14.5 | | |||
| Slit3 | OLF | Olfactory bulb | 68.92 | |
| 72.9 | | |||
| Slit3 | P | Pons | 15.47 | |
| 17.24 | | |||
| Slit3 | PAL | Pallidum | 8.86 | |
| 8.58 | | |||
| Slit3 | RHP | Retrohippocampal region | 76.18 | |
| 87.73 | | |||
| Slit3 | sAMY | Striatum-like amygdalar nuclei | 21.27 | |
| 17.68 | | |||
| Slit3 | STR | Striatum | 83.24 | |
| 70.89 | | |||
| Slit3 | STRd | Striatum dorsal region | 98.53 | |
| 87.56 | | |||
| Slit3 | STRv | Striatum ventral region | 87.78 | |
| 71.53 | | |||
| Slit3 | TH | Thalamus | 24.07 | |
| 22.08 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| SLIT3_HUMAN_297 | 17 | 297 | 313 | GLMEIPANLPEGIVEIR | PRIDE |