AutismKB 2.0

Annotation Detail for SLN


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Basic Information Top
Gene Symbol:SLN ( MGC12301,MGC125854,MGC125855 )
Gene Full Name: sarcolipin
Band: 11q22.3
Quick LinksEntrez ID:6588; OMIM: 602203; Uniprot ID:SARCO_HUMAN; ENSEMBL ID: ENSG00000170290; HGNC ID: 11089
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus34 / 56401260
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult119 / 193912161
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal111 / 336030733
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor41 / 125191327
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue39 / 149255261
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye4 / 21105418
heart20 / 89626223
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver5 / 20774324
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth5 / 6705274
muscle72 / 107715668
nerve1 / 1576863
ovary0 / 1020510 
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205374_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.35
Adipocyte6.35
AdrenalCortex6.95
Adrenalgland11.75
Amygdala6.4
Appendix6.5
AtrioventricularNode5.3
BDCA4+_DentriticCells5.75
Bonemarrow6.6
BronchialEpithelialCells6.35
CD105+_Endothelial6.5
CD14+_Monocytes6.8
CD19+_BCells(neg._sel.)6.5
CD33+_Myeloid8.35
CD34+8.3
CD4+_Tcells5.95
CD56+_NKCells7.5
CD71+_EarlyErythroid4.95
CD8+_Tcells5.7
CardiacMyocytes8.3
Caudatenucleus5.7
Cerebellum5.4
CerebellumPeduncles7.2
CiliaryGanglion7.9
CingulateCortex6.55
Colorectaladenocarcinoma6.4
DorsalRootGanglion5.4
FetalThyroid72.85
Fetalbrain77.15
Fetalliver5.5
Fetallung5.35
GlobusPallidus4.6
Heart23.55
Hypothalamus7.05
Kidney7.6
Leukemia_chronicMyelogenousK-5625.8
Leukemia_promyelocytic-HL-605.65
Leukemialymphoblastic(MOLT-4)5.25
Liver8.4
Lung7.15
Lymphnode7.8
Lymphoma_burkitts(Daudi)8.15
Lymphoma_burkitts(Raji)8.9
MedullaOblongata6.15
OccipitalLobe5.95
OlfactoryBulb5.1
Ovary4.2
Pancreas5.2
PancreaticIslet8.1
ParietalLobe6.8
Pituitary7.45
Placenta6.4
Pons6.05
PrefrontalCortex8.15
Prostate7.9
Salivarygland5.35
SkeletalMuscle5721.6
Skin5
SmoothMuscle7.75
Spinalcord6.85
SubthalamicNucleus6.6
SuperiorCervicalGanglion7.05
TemporalLobe5.8
Testis29.15
TestisGermCell5.3
TestisIntersitial5.4
TestisLeydigCell6.65
TestisSeminiferousTubule5.55
Thalamus6.45
Thymus5.1
Thyroid166.85
Tongue2482.6
Tonsil6.15
Trachea9.65
TrigeminalGanglion6.85
Uterus5
UterusCorpus5.7
WholeBlood7
Wholebrain5.3
colon6.4
pineal_day7.4
pineal_night6.94
retina8.475
small_intestine6.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12985_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.88 ± 1.46
Basal Forebrain3.39 ± 0.31
Basal Part of Pons3.19 ± 0.56
Cerebellar Cortex4.53 ± 0.69
Cerebellar Nuclei3.64 ± 0.93
Claustrum4.48 ± 1.37
Epithalamus3.24 ± 1.06
Frontal Lobe4.56 ± 1.01
Globus Pallidus1.7 ± 0.68
Hypothalamus3.61 ± 1
Insula4.89 ± 0.62
Limbic Lobe3.81 ± 1.39
Mesencephalon3.94 ± 1.17
Myelencephalon3.65 ± 0.97
Occipital Lobe2.19 ± 1.36
Parietal Lobe3.11 ± 1.1
Pontine Tegmentum3.79 ± 1.02
Striatum1.59 ± 1.11
Subthalamus3.81 ± 1.11
Temporal Lobe4.02 ± 1.05
Thalamus3.35 ± 0.9
White Matter1.92 ± 0.99
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
SlnCBCerebellum1.3
1.8
SlnCTXCerebral cortex1.56
2.2
SlnHIPHippocampal region0.46
0.6
SlnHPFHippocampal formation0.34
0.41
SlnHYHypothalamus0.08
0.17
SlnLSXLateral septal complex2.05
2.43
SlnMBMidbrain0.42
0.89
SlnMYMedulla0.94
1.39
SlnOLFOlfactory bulb1.98
2.08
SlnPPons0.4
0.52
SlnPALPallidum0.54
0.91
SlnRHPRetrohippocampal region0.16
0.18
SlnsAMYStriatum-like amygdalar nuclei0.11
0.12
SlnSTRStriatum0.41
0.39
SlnSTRdStriatum dorsal region0.21
0.19
SlnSTRvStriatum ventral region0.56
0.38
SlnTHThalamus0.22
0.23
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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