Annotation Detail for PLEKHA3
Basic Information Top
| Gene Symbol: | PLEKHA3 ( FAPP1,FLJ20067 ) |
|---|---|
| Gene Full Name: | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 |
| Band: | 2q31.2 |
| Quick Links | Entrez ID:65977; OMIM: 607774; Uniprot ID:PKHA3_HUMAN; ENSEMBL ID: ENSG00000116095; HGNC ID: 14338 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.41086
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 25 / 564012 | 44 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 41 / 1939121 | 21 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 |  |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 13 / 263845 | 49 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 96 / 3360307 | 28 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 4 / 124949 | 32 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 1 / 123478 | 8 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 33 / 1100989 | 29 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 6 / 211054 | 28 | |
| heart | 2 / 89626 | 22 | |
| intestine | 7 / 234472 | 29 | |
| kidney | 9 / 211777 | 42 | |
| larynx | 0 / 24145 | 0 | |
| liver | 3 / 207743 | 14 | |
| lung | 46 / 336974 | 136 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 6 / 91610 | 65 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 7 / 214812 | 32 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 3 / 280825 | 10 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 4 / 210574 | 18 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 9 / 330442 | 27 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 3 / 51780 | 57 | |
Microarray in - Probe name: A_32_P209206
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.31 ± 0.58 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.86 ± 0.36 | |
| Basal Part of Pons | 2.88 ± 0.53 | |
| Cerebellar Cortex | 3.05 ± 0.57 | |
| Cerebellar Nuclei | 3.03 ± 0.33 | |
| Claustrum | 3.3 ± 0.74 | |
| Epithalamus | 3.03 ± 0.55 | |
| Frontal Lobe | 3 ± 0.56 | |
| Globus Pallidus | 2.86 ± 0.6 | |
| Hypothalamus | 3.09 ± 0.62 | |
| Insula | 2.9 ± 0.62 | |
| Limbic Lobe | 3.18 ± 0.46 | |
| Mesencephalon | 3.13 ± 0.69 | |
| Myelencephalon | 3.06 ± 0.58 | |
| Occipital Lobe | 3.28 ± 0.78 | |
| Parietal Lobe | 3.01 ± 0.57 | |
| Pontine Tegmentum | 3.05 ± 0.6 | |
| Striatum | 3.36 ± 0.53 | |
| Subthalamus | 2.73 ± 0.88 | |
| Temporal Lobe | 3.04 ± 0.58 | |
| Thalamus | 3 ± 0.51 | |
| White Matter | 3.48 ± 0.48 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Plekha3 | CB | Cerebellum | 4.14 | |
| 3.56 | | |||
| Plekha3 | CTX | Cerebral cortex | 6.62 | |
| 2.63 | | |||
| Plekha3 | HIP | Hippocampal region | 6.58 | |
| 4.65 | | |||
| Plekha3 | HPF | Hippocampal formation | 5.16 | |
| 3.15 | | |||
| Plekha3 | HY | Hypothalamus | 4.42 | |
| 1.33 | | |||
| Plekha3 | LSX | Lateral septal complex | 2.83 | |
| 0.63 | | |||
| Plekha3 | MB | Midbrain | 2.11 | |
| 0.93 | | |||
| Plekha3 | MY | Medulla | 8.32 | |
| 4.43 | | |||
| Plekha3 | OLF | Olfactory bulb | 9.85 | |
| 4.48 | | |||
| Plekha3 | P | Pons | 4.67 | |
| 2.21 | | |||
| Plekha3 | PAL | Pallidum | 1.36 | |
| 0.43 | | |||
| Plekha3 | RHP | Retrohippocampal region | 2.98 | |
| 1.17 | | |||
| Plekha3 | sAMY | Striatum-like amygdalar nuclei | 0.57 | |
| 0.29 | | |||
| Plekha3 | STR | Striatum | 1.12 | |
| 0.44 | | |||
| Plekha3 | STRd | Striatum dorsal region | 0.92 | |
| 0.45 | | |||
| Plekha3 | STRv | Striatum ventral region | 1.44 | |
| 0.37 | | |||
| Plekha3 | TH | Thalamus | 4.69 | |
| 1.72 | |