AutismKB 2.0

Annotation Detail for GRAMD3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GRAMD3 ( FLJ21313,NS3TP2 )
Gene Full Name: GRAM domain containing 3
Band: 5q23.2
Quick LinksEntrez ID:65983; OMIM: NA; Uniprot ID:GRAM3_HUMAN; ENSEMBL ID: ENSG00000155324; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus20 / 56401235
neonate4 / 31097128
infant0 / 236200 
juvenile0 / 555560 
adult118 / 193912160
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor9 / 26384534
glioma8 / 10688374
head and neck tumor3 / 13630222
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal234 / 336030769
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites1 / 4001524
bladder3 / 29757100
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain84 / 110098976
cervix1 / 4817120
connective tissue6 / 14925540
ear1 / 1621261
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye3 / 21105414
heart3 / 8962633
intestine10 / 23447242
kidney19 / 21177789
larynx0 / 241450 
liver7 / 20774333
lung7 / 33697420
lymph0 / 442700 
lymph node2 / 9161021
mammary gland10 / 15327165
mouth2 / 6705229
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta59 / 280825210
prostate12 / 18934563
salivary gland1 / 2015549
skin14 / 21057466
spleen2 / 5395237
stomach2 / 9661920
testis6 / 33044218
thymus2 / 8113124
thyroid4 / 4747384
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord0 / 136800 
uterus23 / 23287898
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218706_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts51.55
Adipocyte37.45
AdrenalCortex16.7
Adrenalgland15.25
Amygdala249.65
Appendix20.9
AtrioventricularNode18.5
BDCA4+_DentriticCells23.1
Bonemarrow12.2
BronchialEpithelialCells38.6
CD105+_Endothelial10.25
CD14+_Monocytes13.3
CD19+_BCells(neg._sel.)9.95
CD33+_Myeloid13.9
CD34+14.8
CD4+_Tcells13.7
CD56+_NKCells14.55
CD71+_EarlyErythroid10.6
CD8+_Tcells12.5
CardiacMyocytes21.55
Caudatenucleus51.2
Cerebellum10.75
CerebellumPeduncles18.3
CiliaryGanglion16.4
CingulateCortex25.3
Colorectaladenocarcinoma12.35
DorsalRootGanglion18.4
FetalThyroid37.6
Fetalbrain13.45
Fetalliver12.1
Fetallung14.1
GlobusPallidus47.85
Heart18.15
Hypothalamus88.75
Kidney15.9
Leukemia_chronicMyelogenousK-56210.3
Leukemia_promyelocytic-HL-6010.75
Leukemialymphoblastic(MOLT-4)8.2
Liver16.25
Lung14.15
Lymphnode10.25
Lymphoma_burkitts(Daudi)14.15
Lymphoma_burkitts(Raji)17.4
MedullaOblongata30.4
OccipitalLobe50.2
OlfactoryBulb99.35
Ovary105.4
Pancreas10.6
PancreaticIslet22.8
ParietalLobe24.2
Pituitary15.9
Placenta268
Pons33.35
PrefrontalCortex330.25
Prostate23.3
Salivarygland16.85
SkeletalMuscle13.6
Skin15.9
SmoothMuscle15.1
Spinalcord264.2
SubthalamicNucleus12.8
SuperiorCervicalGanglion20.45
TemporalLobe16
Testis9.9
TestisGermCell10.75
TestisIntersitial10.8
TestisLeydigCell13.05
TestisSeminiferousTubule11
Thalamus46.3
Thymus9.9
Thyroid115.9
Tongue16.15
Tonsil15.35
Trachea62.9
TrigeminalGanglion23.4
Uterus86.5
UterusCorpus26.45
WholeBlood12.65
Wholebrain56.35
colon75.6
pineal_day150.96
pineal_night58.34
retina200.225
small_intestine73
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P22350
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.74 ± 0.44
Basal Forebrain8.02 ± 0.31
Basal Part of Pons6.98 ± 0.46
Cerebellar Cortex6.77 ± 0.38
Cerebellar Nuclei7.23 ± 0.64
Claustrum7.35 ± 0.56
Epithalamus8.85 ± 0.46
Frontal Lobe7.31 ± 0.52
Globus Pallidus8.87 ± 0.4
Hypothalamus7.57 ± 0.49
Insula7.26 ± 0.27
Limbic Lobe7.19 ± 0.67
Mesencephalon7.7 ± 0.57
Myelencephalon7.63 ± 0.6
Occipital Lobe7.98 ± 0.67
Parietal Lobe7.5 ± 0.53
Pontine Tegmentum7.5 ± 0.44
Striatum8.28 ± 0.56
Subthalamus7.06 ± 0.29
Temporal Lobe7.24 ± 0.51
Thalamus7.75 ± 0.45
White Matter8.33 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gramd3CBCerebellum5.17
5.48
Gramd3CTXCerebral cortex2.15
1.96
Gramd3HIPHippocampal region2.35
2.41
Gramd3HPFHippocampal formation1.9
1.87
Gramd3HYHypothalamus1.37
1.13
Gramd3LSXLateral septal complex2.61
2.35
Gramd3MBMidbrain1.56
1.46
Gramd3MYMedulla2.75
2.35
Gramd3OLFOlfactory bulb2.3
2.45
Gramd3PPons1.54
1.51
Gramd3PALPallidum1.54
1.13
Gramd3RHPRetrohippocampal region1.22
1.19
Gramd3sAMYStriatum-like amygdalar nuclei0.76
0.64
Gramd3STRStriatum1.73
1.44
Gramd3STRdStriatum dorsal region1.78
1.47
Gramd3STRvStriatum ventral region1.26
0.81
Gramd3THThalamus1.63
1.35
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved