AutismKB 2.0

Annotation Detail for ZBTB10


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Basic Information Top
Gene Symbol:ZBTB10 ( FLJ12752,RINZF )
Gene Full Name: zinc finger and BTB domain containing 10
Band: 8q21.13
Quick LinksEntrez ID:65986; OMIM: NA; Uniprot ID:ZBT10_HUMAN; ENSEMBL ID: ENSG00000205189; HGNC ID: 30953
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor9 / 26384534
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal56 / 336030716
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain10 / 11009899
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung2 / 3369745
lymph1 / 4427022
lymph node4 / 9161043
mammary gland1 / 1532716
mouth0 / 670520 
muscle6 / 10771555
nerve1 / 1576863
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate11 / 18934558
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis13 / 33044239
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219312_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.45
Adipocyte6.55
AdrenalCortex8.35
Adrenalgland6.1
Amygdala6.7
Appendix9.4
AtrioventricularNode8.95
BDCA4+_DentriticCells7.45
Bonemarrow7.4
BronchialEpithelialCells6.4
CD105+_Endothelial6.55
CD14+_Monocytes7.25
CD19+_BCells(neg._sel.)8.15
CD33+_Myeloid8.4
CD34+8
CD4+_Tcells6.8
CD56+_NKCells7.5
CD71+_EarlyErythroid6.6
CD8+_Tcells6.05
CardiacMyocytes11.25
Caudatenucleus6
Cerebellum5.55
CerebellumPeduncles8.3
CiliaryGanglion6.4
CingulateCortex7.1
Colorectaladenocarcinoma6.75
DorsalRootGanglion6
FetalThyroid6.8
Fetalbrain6.4
Fetalliver6.1
Fetallung5.1
GlobusPallidus5.45
Heart11.8
Hypothalamus6.9
Kidney6.15
Leukemia_chronicMyelogenousK-5626
Leukemia_promyelocytic-HL-605.95
Leukemialymphoblastic(MOLT-4)5.15
Liver10.25
Lung7.3
Lymphnode5.5
Lymphoma_burkitts(Daudi)8.95
Lymphoma_burkitts(Raji)10.5
MedullaOblongata6
OccipitalLobe6
OlfactoryBulb5.2
Ovary6.35
Pancreas6.25
PancreaticIslet7.35
ParietalLobe7.65
Pituitary7.95
Placenta6.7
Pons6.75
PrefrontalCortex7.9
Prostate8.6
Salivarygland5.75
SkeletalMuscle11.2
Skin6.6
SmoothMuscle7.55
Spinalcord7.2
SubthalamicNucleus7.5
SuperiorCervicalGanglion17.35
TemporalLobe6.55
Testis5.7
TestisGermCell5.35
TestisIntersitial6.35
TestisLeydigCell8.05
TestisSeminiferousTubule5.85
Thalamus6.95
Thymus5
Thyroid8.1
Tongue7.65
Tonsil6.7
Trachea5.5
TrigeminalGanglion8.8
Uterus6
UterusCorpus6.8
WholeBlood7.2
Wholebrain5.3
colon8.95
pineal_day8.4
pineal_night8.14
retina8.125
small_intestine6.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P10327
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.07 ± 0.94
Basal Forebrain2.33 ± 0.26
Basal Part of Pons2.16 ± 0.4
Cerebellar Cortex2.75 ± 0.75
Cerebellar Nuclei2.75 ± 0.72
Claustrum3.23 ± 0.8
Epithalamus2.3 ± 0.64
Frontal Lobe2.43 ± 0.72
Globus Pallidus2.56 ± 0.66
Hypothalamus2.38 ± 0.68
Insula2.45 ± 0.61
Limbic Lobe2.48 ± 0.67
Mesencephalon2.63 ± 0.75
Myelencephalon2.54 ± 0.66
Occipital Lobe2.56 ± 0.84
Parietal Lobe2.51 ± 0.79
Pontine Tegmentum2.56 ± 0.69
Striatum2.56 ± 0.73
Subthalamus2.75 ± 0.87
Temporal Lobe2.46 ± 0.68
Thalamus2.46 ± 0.68
White Matter2.77 ± 0.64
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zbtb10CBCerebellum2.13
3.31
Zbtb10CTXCerebral cortex5.15
4.04
Zbtb10HIPHippocampal region4.43
4.36
Zbtb10HPFHippocampal formation6.72
6.37
Zbtb10HYHypothalamus0.21
0.51
Zbtb10LSXLateral septal complex0.29
1.4
Zbtb10MBMidbrain0.83
1.55
Zbtb10MYMedulla3.08
4.25
Zbtb10OLFOlfactory bulb6.27
5.93
Zbtb10PPons0.57
0.72
Zbtb10PALPallidum0.68
0.66
Zbtb10RHPRetrohippocampal region11.28
9.72
Zbtb10sAMYStriatum-like amygdalar nuclei0.93
0.71
Zbtb10STRStriatum3.02
2.42
Zbtb10STRdStriatum dorsal region4.16
3.37
Zbtb10STRvStriatum ventral region1.4
0.88
Zbtb10THThalamus1.36
1.6
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00140876 20 278 297 TPADGGSVDLPPVGHDELSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018