AutismKB 2.0

Annotation Detail for FAM173A


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Basic Information Top
Gene Symbol:FAM173A ( C16orf24,MGC2494 )
Gene Full Name: family with sequence similarity 173, member A
Band: 16p13.3
Quick LinksEntrez ID:65990; OMIM: NA; Uniprot ID:F173A_HUMAN; ENSEMBL ID: ENSG00000103254; HGNC ID: 14152
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult19 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal33 / 33603079
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain21 / 110098919
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine2 / 2344728
kidney5 / 21177723
larynx0 / 241450 
liver0 / 2077430 
lung11 / 33697432
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate2 / 18934510
salivary gland1 / 2015549
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219709_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts96.8
Adipocyte14.85
AdrenalCortex18.55
Adrenalgland14.8
Amygdala68.2
Appendix10.25
AtrioventricularNode12.8
BDCA4+_DentriticCells72.45
Bonemarrow13.95
BronchialEpithelialCells15.6
CD105+_Endothelial40.15
CD14+_Monocytes72.15
CD19+_BCells(neg._sel.)93.25
CD33+_Myeloid54.05
CD34+35.2
CD4+_Tcells64.05
CD56+_NKCells129.95
CD71+_EarlyErythroid13.5
CD8+_Tcells86.9
CardiacMyocytes19.15
Caudatenucleus14.6
Cerebellum12.8
CerebellumPeduncles19.8
CiliaryGanglion11.9
CingulateCortex36.95
Colorectaladenocarcinoma17.3
DorsalRootGanglion12.85
FetalThyroid19.2
Fetalbrain15.95
Fetalliver14.05
Fetallung12.6
GlobusPallidus13.3
Heart101.35
Hypothalamus22.8
Kidney14.3
Leukemia_chronicMyelogenousK-56215.45
Leukemia_promyelocytic-HL-6015.45
Leukemialymphoblastic(MOLT-4)7.8
Liver104.55
Lung80.4
Lymphnode15.5
Lymphoma_burkitts(Daudi)17.25
Lymphoma_burkitts(Raji)37.65
MedullaOblongata15.6
OccipitalLobe16.85
OlfactoryBulb12.35
Ovary11.05
Pancreas14.05
PancreaticIslet14.85
ParietalLobe17.95
Pituitary20.05
Placenta14.15
Pons16.2
PrefrontalCortex33.25
Prostate53.15
Salivarygland13.05
SkeletalMuscle18.85
Skin12.95
SmoothMuscle16.4
Spinalcord20.45
SubthalamicNucleus20.2
SuperiorCervicalGanglion17.55
TemporalLobe29.05
Testis34.4
TestisGermCell13.15
TestisIntersitial40.55
TestisLeydigCell30.55
TestisSeminiferousTubule27
Thalamus17.05
Thymus15.95
Thyroid80.95
Tongue13.8
Tonsil14.2
Trachea11.5
TrigeminalGanglion16.75
Uterus11.95
UterusCorpus13.7
WholeBlood16.05
Wholebrain76.85
colon19.45
pineal_day35.32
pineal_night22.56
retina24.825
small_intestine17.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5882_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.84 ± 0.43
Basal Forebrain8.05 ± 0.09
Basal Part of Pons8.13 ± 0.3
Cerebellar Cortex7.91 ± 0.22
Cerebellar Nuclei8.27 ± 0.19
Claustrum7.69 ± 0.47
Epithalamus8.14 ± 0.26
Frontal Lobe8.27 ± 0.33
Globus Pallidus8.23 ± 0.35
Hypothalamus8.36 ± 0.32
Insula8.25 ± 0.27
Limbic Lobe7.96 ± 0.41
Mesencephalon8.03 ± 0.41
Myelencephalon8.12 ± 0.33
Occipital Lobe7.83 ± 0.25
Parietal Lobe8.1 ± 0.34
Pontine Tegmentum8.09 ± 0.36
Striatum7.68 ± 0.33
Subthalamus8.32 ± 0.22
Temporal Lobe8.2 ± 0.3
Thalamus8.13 ± 0.3
White Matter8.27 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
BC008155CBCerebellum17.85
27.15
BC008155CTXCerebral cortex19.38
12.74
BC008155HIPHippocampal region14.79
12.65
BC008155HPFHippocampal formation13.51
10.64
BC008155HYHypothalamus16.26
12.19
BC008155LSXLateral septal complex9.22
6.3
BC008155MBMidbrain15.56
13.18
BC008155MYMedulla23.87
24.86
BC008155OLFOlfactory bulb17.83
12.53
BC008155PPons22.95
22.73
BC008155PALPallidum17.05
14.43
BC008155RHPRetrohippocampal region10.9
7.48
BC008155sAMYStriatum-like amygdalar nuclei8.63
5.9
BC008155STRStriatum5.13
3.57
BC008155STRdStriatum dorsal region3.96
2.94
BC008155STRvStriatum ventral region5.3
3.21
BC008155THThalamus18.59
13.12
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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