AutismKB 2.0

Annotation Detail for MRPS34


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Basic Information Top
Gene Symbol:MRPS34 ( MGC2616,MRP-S12,MRP-S34,MRPS12 )
Gene Full Name: mitochondrial ribosomal protein S34
Band: 16p13.3
Quick LinksEntrez ID:65993; OMIM: 611994; Uniprot ID:RT34_HUMAN; ENSEMBL ID: ENSG00000074071; HGNC ID: 16618
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult100 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor9 / 9417895
cervical tumor2 / 3436658
chondrosarcoma7 / 8282384
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor10 / 26384537
glioma11 / 106883102
head and neck tumor3 / 13630222
kidney tumor9 / 68959130
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor18 / 103127174
lymphoma8 / 71755111
non-neoplasia1 / 9725010
normal96 / 336030728
ovarian tumor3 / 7668239
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS19 / 125680151
prostate cancer12 / 102680116
retinoblastoma17 / 46356366
skin tumor16 / 124949128
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites5 / 40015124
bladder0 / 297570 
blood4 / 12347832
bone5 / 7165569
bone marrow2 / 4880140
brain33 / 110098929
cervix4 / 4817183
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye24 / 211054113
heart1 / 8962611
intestine6 / 23447225
kidney16 / 21177775
larynx0 / 241450 
liver4 / 20774319
lung31 / 33697491
lymph4 / 4427090
lymph node5 / 9161054
mammary gland10 / 15327165
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary4 / 10205139
pancreas15 / 21481269
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta20 / 28082571
prostate21 / 189345110
salivary gland2 / 2015599
skin18 / 21057485
spleen0 / 539520 
stomach2 / 9661920
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218112_at
Cell line Expression level Expression bar
721_B_lymphoblasts211.45
Adipocyte29.5
AdrenalCortex40.3
Adrenalgland38.7
Amygdala30.25
Appendix16.95
AtrioventricularNode15.8
BDCA4+_DentriticCells85.6
Bonemarrow27.65
BronchialEpithelialCells41.15
CD105+_Endothelial139.85
CD14+_Monocytes119
CD19+_BCells(neg._sel.)38.8
CD33+_Myeloid56.3
CD34+112.3
CD4+_Tcells52.8
CD56+_NKCells72.95
CD71+_EarlyErythroid47.85
CD8+_Tcells35.3
CardiacMyocytes24
Caudatenucleus25.25
Cerebellum20.2
CerebellumPeduncles31.8
CiliaryGanglion44.2
CingulateCortex25.2
Colorectaladenocarcinoma54.8
DorsalRootGanglion18.75
FetalThyroid19.9
Fetalbrain28.3
Fetalliver16.15
Fetallung18.75
GlobusPallidus16.9
Heart79.85
Hypothalamus33
Kidney22.35
Leukemia_chronicMyelogenousK-56255.8
Leukemia_promyelocytic-HL-60123.7
Leukemialymphoblastic(MOLT-4)28.9
Liver75.3
Lung73.1
Lymphnode28.9
Lymphoma_burkitts(Daudi)67.65
Lymphoma_burkitts(Raji)191.55
MedullaOblongata19.15
OccipitalLobe25.45
OlfactoryBulb21.95
Ovary11.4
Pancreas26.3
PancreaticIslet26.55
ParietalLobe23.6
Pituitary26.1
Placenta27
Pons24.2
PrefrontalCortex26.7
Prostate55.65
Salivarygland15
SkeletalMuscle27.1
Skin17.1
SmoothMuscle39.65
Spinalcord30.2
SubthalamicNucleus41.7
SuperiorCervicalGanglion18.25
TemporalLobe24.95
Testis16.9
TestisGermCell18.7
TestisIntersitial18.05
TestisLeydigCell15.7
TestisSeminiferousTubule15.5
Thalamus31.65
Thymus28.1
Thyroid51.4
Tongue26.4
Tonsil24.15
Trachea19.3
TrigeminalGanglion24.55
Uterus18.25
UterusCorpus16.25
WholeBlood31.15
Wholebrain53.2
colon24.2
pineal_day38.38
pineal_night38.26
retina23.3
small_intestine24.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5065_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.86 ± 0.28
Basal Forebrain7.94 ± 0.15
Basal Part of Pons8.27 ± 0.24
Cerebellar Cortex8.2 ± 0.26
Cerebellar Nuclei8.21 ± 0.15
Claustrum7.98 ± 0.35
Epithalamus7.95 ± 0.44
Frontal Lobe8.09 ± 0.31
Globus Pallidus7.75 ± 0.21
Hypothalamus8.01 ± 0.45
Insula8.01 ± 0.32
Limbic Lobe8.02 ± 0.24
Mesencephalon8 ± 0.27
Myelencephalon8.05 ± 0.3
Occipital Lobe7.92 ± 0.24
Parietal Lobe7.99 ± 0.23
Pontine Tegmentum8.01 ± 0.24
Striatum7.97 ± 0.18
Subthalamus7.94 ± 0.35
Temporal Lobe8.08 ± 0.26
Thalamus8.11 ± 0.24
White Matter7.98 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mrps34CBCerebellum20.06
26.93
Mrps34CTXCerebral cortex56.51
47.85
Mrps34HIPHippocampal region41.37
66.03
Mrps34HPFHippocampal formation40.38
51.82
Mrps34HYHypothalamus20.72
18.66
Mrps34LSXLateral septal complex10.64
9.13
Mrps34MBMidbrain23.26
24.72
Mrps34MYMedulla19.57
25.26
Mrps34OLFOlfactory bulb29.77
26.86
Mrps34PPons23.79
30.96
Mrps34PALPallidum18.75
19.94
Mrps34RHPRetrohippocampal region38.42
35.12
Mrps34sAMYStriatum-like amygdalar nuclei31.85
26.58
Mrps34STRStriatum13.96
11.44
Mrps34STRdStriatum dorsal region12.66
10.4
Mrps34STRvStriatum ventral region11.57
9.05
Mrps34THThalamus23.46
21.97
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00080875 14 100 113 VRPDYTAQNLDHGK Peptide Atlas
RT34_HUMAN_63 15 63 77 LLQLLGRLPLFGLGR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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