AutismKB 2.0

Annotation Detail for LRRC61


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Basic Information Top
Gene Symbol:LRRC61 ( FLJ22216,FLJ31392,HSPC295,MGC3036 )
Gene Full Name: leucine rich repeat containing 61
Band: 7q36.1
Quick LinksEntrez ID:65999; OMIM: NA; Uniprot ID:LRC61_HUMAN; ENSEMBL ID: ENSG00000127399; HGNC ID: 21704
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile6 / 55556107
adult72 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor4 / 34366116
chondrosarcoma2 / 8282324
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor21 / 26384579
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor8 / 10312777
lymphoma5 / 7175569
non-neoplasia2 / 9725020
normal91 / 336030727
ovarian tumor9 / 76682117
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS28 / 125680222
prostate cancer2 / 10268019
retinoblastoma3 / 4635664
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites2 / 4001549
bladder0 / 297570 
blood10 / 12347880
bone0 / 716550 
bone marrow1 / 4880120
brain34 / 110098930
cervix8 / 48171166
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye5 / 21105423
heart1 / 8962611
intestine16 / 23447268
kidney5 / 21177723
larynx0 / 241450 
liver2 / 2077439
lung12 / 33697435
lymph1 / 4427022
lymph node3 / 9161032
mammary gland5 / 15327132
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary10 / 10205197
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta8 / 28082528
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen3 / 5395255
stomach0 / 966190 
testis14 / 33044242
thymus5 / 8113161
thyroid1 / 4747321
tonsil1 / 1699958
trachea3 / 5241357
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218907_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts84
Adipocyte18.7
AdrenalCortex33.9
Adrenalgland15.9
Amygdala21.95
Appendix24.25
AtrioventricularNode18.45
BDCA4+_DentriticCells14
Bonemarrow18.75
BronchialEpithelialCells15.55
CD105+_Endothelial19.55
CD14+_Monocytes20.35
CD19+_BCells(neg._sel.)43.15
CD33+_Myeloid28.75
CD34+34.75
CD4+_Tcells20.95
CD56+_NKCells21.35
CD71+_EarlyErythroid17.25
CD8+_Tcells18.6
CardiacMyocytes40.15
Caudatenucleus16.95
Cerebellum15.6
CerebellumPeduncles21.05
CiliaryGanglion26.4
CingulateCortex17.95
Colorectaladenocarcinoma94.8
DorsalRootGanglion14.15
FetalThyroid37.6
Fetalbrain23.9
Fetalliver13.95
Fetallung15.6
GlobusPallidus13.35
Heart40.85
Hypothalamus16.45
Kidney15.05
Leukemia_chronicMyelogenousK-56260.55
Leukemia_promyelocytic-HL-6023.05
Leukemialymphoblastic(MOLT-4)40.6
Liver71.35
Lung21.5
Lymphnode16.2
Lymphoma_burkitts(Daudi)25.65
Lymphoma_burkitts(Raji)89.15
MedullaOblongata17.35
OccipitalLobe16.7
OlfactoryBulb16.25
Ovary23.1
Pancreas28.95
PancreaticIslet21.3
ParietalLobe19.1
Pituitary26.85
Placenta19.6
Pons17.45
PrefrontalCortex24
Prostate18.5
Salivarygland18.6
SkeletalMuscle30.4
Skin21.45
SmoothMuscle18.45
Spinalcord15.8
SubthalamicNucleus20.3
SuperiorCervicalGanglion20.85
TemporalLobe15.15
Testis21
TestisGermCell12.95
TestisIntersitial21.05
TestisLeydigCell27.8
TestisSeminiferousTubule20.05
Thalamus17.75
Thymus16.4
Thyroid44.75
Tongue19.9
Tonsil18.05
Trachea15.9
TrigeminalGanglion37.1
Uterus16.7
UterusCorpus17.85
WholeBlood21.05
Wholebrain13.25
colon18.4
pineal_day87.16
pineal_night70.64
retina20.675
small_intestine11.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P235840
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.23 ± 0.57
Basal Forebrain2.77 ± 0.47
Basal Part of Pons2.54 ± 0.75
Cerebellar Cortex2.81 ± 0.64
Cerebellar Nuclei3.11 ± 0.59
Claustrum3.13 ± 0.66
Epithalamus2.21 ± 0.88
Frontal Lobe2.68 ± 0.68
Globus Pallidus3.08 ± 0.83
Hypothalamus2.84 ± 0.85
Insula2.77 ± 0.62
Limbic Lobe2.89 ± 0.73
Mesencephalon2.76 ± 0.71
Myelencephalon2.82 ± 0.67
Occipital Lobe2.85 ± 0.93
Parietal Lobe2.74 ± 0.76
Pontine Tegmentum2.73 ± 0.66
Striatum2.65 ± 0.7
Subthalamus2.91 ± 1.17
Temporal Lobe2.63 ± 0.74
Thalamus2.69 ± 0.65
White Matter3.33 ± 0.14
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lrrc61CBCerebellum0.58
0.65
Lrrc61CTXCerebral cortex0.47
0.39
Lrrc61HIPHippocampal region2.35
2.09
Lrrc61HPFHippocampal formation1.53
1.24
Lrrc61HYHypothalamus0.13
0.11
Lrrc61LSXLateral septal complex0.03
0
Lrrc61MBMidbrain0.82
1.3
Lrrc61MYMedulla0.77
1.2
Lrrc61OLFOlfactory bulb0.59
1.17
Lrrc61PPons0.89
1.36
Lrrc61PALPallidum0.14
0.12
Lrrc61RHPRetrohippocampal region0.29
0.2
Lrrc61sAMYStriatum-like amygdalar nuclei0.11
0.14
Lrrc61STRStriatum0.09
0.11
Lrrc61STRdStriatum dorsal region0.07
0.06
Lrrc61STRvStriatum ventral region0.14
0.2
Lrrc61THThalamus0.2
0.14
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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