AutismKB 2.0

Annotation Detail for CYP4F12


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Basic Information Top
Gene Symbol:CYP4F12 ( F22329_1 )
Gene Full Name: cytochrome P450, family 4, subfamily F, polypeptide 12
Band: 19p13.12
Quick LinksEntrez ID:66002; OMIM: 611485; Uniprot ID:CP4FC_HUMAN; ENSEMBL ID: ENSG00000186204; HGNC ID: 18857
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor5 / 11424643
esophageal tumor2 / 17290115
gastrointestinal tumor10 / 11936983
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal36 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites9 / 40015224
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus2 / 2020998
eye1 / 2110544
heart0 / 896260 
intestine11 / 23447246
kidney1 / 2117774
larynx0 / 241450 
liver9 / 20774343
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206539_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts88.15
Adipocyte124.45
AdrenalCortex145.75
Adrenalgland135.9
Amygdala71
Appendix155.9
AtrioventricularNode296.55
BDCA4+_DentriticCells72
Bonemarrow110.55
BronchialEpithelialCells98.85
CD105+_Endothelial78.3
CD14+_Monocytes86.3
CD19+_BCells(neg._sel.)81.85
CD33+_Myeloid119.45
CD34+107.25
CD4+_Tcells103
CD56+_NKCells99.55
CD71+_EarlyErythroid91.55
CD8+_Tcells85.65
CardiacMyocytes119.7
Caudatenucleus99.35
Cerebellum89.45
CerebellumPeduncles125.7
CiliaryGanglion193.9
CingulateCortex163.2
Colorectaladenocarcinoma58.6
DorsalRootGanglion162.3
FetalThyroid103.2
Fetalbrain97.95
Fetalliver144.5
Fetallung73.1
GlobusPallidus88.25
Heart151.9
Hypothalamus111.75
Kidney134.8
Leukemia_chronicMyelogenousK-56297.85
Leukemia_promyelocytic-HL-6094.05
Leukemialymphoblastic(MOLT-4)81.3
Liver1077.8
Lung65.1
Lymphnode87.35
Lymphoma_burkitts(Daudi)135.8
Lymphoma_burkitts(Raji)136.25
MedullaOblongata102.25
OccipitalLobe94.1
OlfactoryBulb104.65
Ovary79.95
Pancreas98.8
PancreaticIslet114.5
ParietalLobe159.05
Pituitary180.55
Placenta82.6
Pons162.1
PrefrontalCortex126.9
Prostate74.9
Salivarygland137.45
SkeletalMuscle194.55
Skin211.55
SmoothMuscle113.7
Spinalcord129.3
SubthalamicNucleus125.2
SuperiorCervicalGanglion229.75
TemporalLobe130.45
Testis89.25
TestisGermCell83.85
TestisIntersitial118.6
TestisLeydigCell114.9
TestisSeminiferousTubule146.6
Thalamus110.85
Thymus74.25
Thyroid41.05
Tongue180.6
Tonsil105.65
Trachea93.35
TrigeminalGanglion219.25
Uterus75.3
UterusCorpus162.65
WholeBlood75.55
Wholebrain80.2
colon133.9
pineal_day130.44
pineal_night131.42
retina128.65
small_intestine263.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P108280
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.28 ± 0.98
Basal Forebrain1.92 ± 0.46
Basal Part of Pons1.56 ± 0.44
Cerebellar Cortex1.76 ± 0.66
Cerebellar Nuclei2.18 ± 0.82
Claustrum2.74 ± 0.81
Epithalamus3.71 ± 0.66
Frontal Lobe1.84 ± 0.75
Globus Pallidus3.39 ± 0.62
Hypothalamus2.13 ± 1.2
Insula1.98 ± 0.66
Limbic Lobe1.98 ± 0.78
Mesencephalon2.25 ± 0.71
Myelencephalon2.16 ± 0.78
Occipital Lobe2.47 ± 0.99
Parietal Lobe2.18 ± 0.82
Pontine Tegmentum2.16 ± 0.82
Striatum2.33 ± 0.83
Subthalamus2.29 ± 0.24
Temporal Lobe1.95 ± 0.68
Thalamus2.13 ± 0.59
White Matter3.43 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cyp4f14CBCerebellum24.54
35.27
Cyp4f14CTXCerebral cortex7.23
5.53
Cyp4f14HIPHippocampal region6.43
9.82
Cyp4f14HPFHippocampal formation5.5
7.04
Cyp4f14HYHypothalamus1.63
1.28
Cyp4f14LSXLateral septal complex1.15
0.96
Cyp4f14MBMidbrain2.99
4.16
Cyp4f14MYMedulla4.81
6.76
Cyp4f14OLFOlfactory bulb9.42
8.37
Cyp4f14PPons2.62
3.17
Cyp4f14PALPallidum1
0.98
Cyp4f14RHPRetrohippocampal region3.77
2.82
Cyp4f14sAMYStriatum-like amygdalar nuclei0.77
0.69
Cyp4f14STRStriatum1.15
1.09
Cyp4f14STRdStriatum dorsal region0.73
0.87
Cyp4f14STRvStriatum ventral region2.19
1.53
Cyp4f14THThalamus1.34
1.15
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CP4FC_HUMAN_491 9 491 499 FLPDHTEPR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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