AutismKB 2.0

Annotation Detail for SNAP25


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Basic Information Top
Gene Symbol:SNAP25 ( FLJ23079,RIC-4,RIC4,SEC9,SNAP,SNAP-25,bA416N4.2,dJ1068F16.2 )
Gene Full Name: synaptosomal-associated protein, 25kDa
Band: 20p12.2
Quick LinksEntrez ID:6616; OMIM: 600322; Uniprot ID:SNP25_HUMAN; ENSEMBL ID: ENSG00000132639; HGNC ID: 11132
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus103 / 564012182
neonate0 / 310970 
infant11 / 23620465
juvenile10 / 55556179
adult314 / 1939121161
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor38 / 263845144
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor186 / 689592697
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia150 / 972501542
normal2094 / 3360307623
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland6 / 33197180
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2761 / 11009892507
cervix0 / 481710 
connective tissue0 / 1492550 
ear2 / 16212123
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye35 / 211054165
heart2 / 8962622
intestine1 / 2344724
kidney192 / 211777906
larynx0 / 241450 
liver4 / 20774319
lung7 / 33697420
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve3 / 15768190
ovary1 / 1020519
pancreas28 / 214812130
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis22 / 33044266
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202507_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.75
Adipocyte8.15
AdrenalCortex7.05
Adrenalgland6.15
Amygdala1797.8
Appendix8.3
AtrioventricularNode5.9
BDCA4+_DentriticCells6.5
Bonemarrow8.95
BronchialEpithelialCells7.3
CD105+_Endothelial5.55
CD14+_Monocytes6.6
CD19+_BCells(neg._sel.)7.5
CD33+_Myeloid8.45
CD34+7.45
CD4+_Tcells7.75
CD56+_NKCells6.1
CD71+_EarlyErythroid4.9
CD8+_Tcells6.7
CardiacMyocytes11.85
Caudatenucleus450.35
Cerebellum2298
CerebellumPeduncles3839.65
CiliaryGanglion11.1
CingulateCortex1404.4
Colorectaladenocarcinoma7.25
DorsalRootGanglion35.9
FetalThyroid8.65
Fetalbrain95.75
Fetalliver6.45
Fetallung5.5
GlobusPallidus1421.75
Heart10.55
Hypothalamus490.9
Kidney6.25
Leukemia_chronicMyelogenousK-5626.55
Leukemia_promyelocytic-HL-606.15
Leukemialymphoblastic(MOLT-4)5.9
Liver17.9
Lung7.85
Lymphnode6.1
Lymphoma_burkitts(Daudi)9.1
Lymphoma_burkitts(Raji)12.7
MedullaOblongata1430.95
OccipitalLobe2187.25
OlfactoryBulb5.3
Ovary7.8
Pancreas6.2
PancreaticIslet45.5
ParietalLobe2402.8
Pituitary85.65
Placenta6.55
Pons1144.6
PrefrontalCortex1758.6
Prostate7.6
Salivarygland5.05
SkeletalMuscle8.85
Skin5.8
SmoothMuscle14.9
Spinalcord67.1
SubthalamicNucleus1736.05
SuperiorCervicalGanglion15.85
TemporalLobe1483
Testis6.75
TestisGermCell5.75
TestisIntersitial6.4
TestisLeydigCell7.3
TestisSeminiferousTubule5.95
Thalamus779.45
Thymus6.15
Thyroid9
Tongue6.7
Tonsil7.2
Trachea8.55
TrigeminalGanglion7.65
Uterus6.05
UterusCorpus8.4
WholeBlood7.85
Wholebrain2321.4
colon8.75
pineal_day873.18
pineal_night717.1
retina106.1
small_intestine8.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15476_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.27 ± 0.79
Basal Forebrain8.85 ± 0.3
Basal Part of Pons9.33 ± 0.43
Cerebellar Cortex9.68 ± 0.26
Cerebellar Nuclei6.9 ± 0.78
Claustrum10.36 ± 0.39
Epithalamus7.73 ± 1.28
Frontal Lobe9.38 ± 0.65
Globus Pallidus6.18 ± 1.28
Hypothalamus8.72 ± 0.63
Insula9.59 ± 0.24
Limbic Lobe10.08 ± 0.53
Mesencephalon8.8 ± 1.01
Myelencephalon8.98 ± 0.87
Occipital Lobe8.46 ± 0.81
Parietal Lobe8.99 ± 0.71
Pontine Tegmentum8.73 ± 0.92
Striatum7.24 ± 1.04
Subthalamus7.46 ± 0.17
Temporal Lobe9.5 ± 0.47
Thalamus9.07 ± 0.79
White Matter6.79 ± 0.94
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Snap25CBCerebellum100
100
Snap25CTXCerebral cortex100
100
Snap25HIPHippocampal region100
100
Snap25HPFHippocampal formation100
100
Snap25HYHypothalamus100
100
Snap25LSXLateral septal complex100
100
Snap25MBMidbrain100
100
Snap25MYMedulla100
100
Snap25OLFOlfactory bulb100
100
Snap25PPons100
100
Snap25PALPallidum100
100
Snap25RHPRetrohippocampal region100
100
Snap25sAMYStriatum-like amygdalar nuclei100
100
Snap25STRStriatum100
100
Snap25STRdStriatum dorsal region100
100
Snap25STRvStriatum ventral region100
100
Snap25THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00621639 15 17 31 RADQLADESLESTRR Peptide Atlas
SNP25_HUMAN_125 11 125 135 EQMAISGGFIR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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