AutismKB 2.0

Annotation Detail for BNIP1


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Basic Information Top
Gene Symbol:BNIP1 ( NIP1,SEC20,TRG-8 )
Gene Full Name: BCL2/adenovirus E1B 19kDa interacting protein 1
Band: 5q35.1
Quick LinksEntrez ID:662; OMIM: 603291; Uniprot ID:SEC20_HUMAN; ENSEMBL ID: ENSG00000113734; HGNC ID: 1082
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus27 / 56401247
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia7 / 9584273
liver tumor10 / 96359103
lung tumor4 / 10312738
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal76 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor7 / 12494956
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood4 / 12347832
bone1 / 7165513
bone marrow0 / 488010 
brain5 / 11009894
cervix6 / 48171124
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye7 / 21105433
heart7 / 8962678
intestine2 / 2344728
kidney6 / 21177728
larynx0 / 241450 
liver12 / 20774357
lung16 / 33697447
lymph5 / 44270112
lymph node7 / 9161076
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas3 / 21481213
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin12 / 21057456
spleen0 / 539520 
stomach0 / 966190 
testis10 / 33044230
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204930_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.1
Adipocyte5.3
AdrenalCortex6.1
Adrenalgland4.85
Amygdala5.85
Appendix5.75
AtrioventricularNode5.65
BDCA4+_DentriticCells5.6
Bonemarrow6.6
BronchialEpithelialCells5.4
CD105+_Endothelial5.9
CD14+_Monocytes6.05
CD19+_BCells(neg._sel.)5.85
CD33+_Myeloid6.6
CD34+7.45
CD4+_Tcells5.9
CD56+_NKCells7.6
CD71+_EarlyErythroid5.25
CD8+_Tcells5.05
CardiacMyocytes8.15
Caudatenucleus5.05
Cerebellum4.6
CerebellumPeduncles6.7
CiliaryGanglion4.25
CingulateCortex6
Colorectaladenocarcinoma5.7
DorsalRootGanglion4.2
FetalThyroid5.75
Fetalbrain5.75
Fetalliver5.55
Fetallung4.15
GlobusPallidus4.3
Heart11.3
Hypothalamus5.95
Kidney4.6
Leukemia_chronicMyelogenousK-5625.85
Leukemia_promyelocytic-HL-607.35
Leukemialymphoblastic(MOLT-4)4.2
Liver8.95
Lung6.05
Lymphnode4.6
Lymphoma_burkitts(Daudi)7.1
Lymphoma_burkitts(Raji)9.25
MedullaOblongata5.15
OccipitalLobe4.95
OlfactoryBulb4.3
Ovary4.35
Pancreas4.4
PancreaticIslet6
ParietalLobe7.6
Pituitary6.6
Placenta5.25
Pons5.7
PrefrontalCortex6.8
Prostate6.45
Salivarygland7.3
SkeletalMuscle8.45
Skin5.25
SmoothMuscle6.2
Spinalcord6
SubthalamicNucleus5.05
SuperiorCervicalGanglion7.85
TemporalLobe5.3
Testis4.9
TestisGermCell4.45
TestisIntersitial5.15
TestisLeydigCell5.65
TestisSeminiferousTubule4.85
Thalamus5.85
Thymus4.2
Thyroid6.75
Tongue5.6
Tonsil5.5
Trachea4.65
TrigeminalGanglion6.55
Uterus4.45
UterusCorpus5.3
WholeBlood5.85
Wholebrain4.8
colon5.65
pineal_day6.68
pineal_night6.74
retina6.75
small_intestine5.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1172_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.44 ± 0.23
Basal Forebrain5.33 ± 0.22
Basal Part of Pons5.47 ± 0.27
Cerebellar Cortex5.24 ± 0.28
Cerebellar Nuclei5.23 ± 0.42
Claustrum5.74 ± 0.57
Epithalamus5.06 ± 0.31
Frontal Lobe5.31 ± 0.28
Globus Pallidus5.67 ± 0.37
Hypothalamus5.39 ± 0.38
Insula5.36 ± 0.27
Limbic Lobe5.46 ± 0.3
Mesencephalon5.42 ± 0.41
Myelencephalon5.35 ± 0.36
Occipital Lobe5.32 ± 0.36
Parietal Lobe5.36 ± 0.38
Pontine Tegmentum5.3 ± 0.34
Striatum5.36 ± 0.33
Subthalamus5.16 ± 0.5
Temporal Lobe5.36 ± 0.33
Thalamus5.25 ± 0.31
White Matter5.93 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Bnip1CBCerebellum2.33
2.32
Bnip1CTXCerebral cortex3.94
2.46
Bnip1HIPHippocampal region3.96
3.19
Bnip1HPFHippocampal formation5.6
4.11
Bnip1HYHypothalamus0.22
0.26
Bnip1LSXLateral septal complex0.39
0.23
Bnip1MBMidbrain0.63
0.58
Bnip1MYMedulla2.24
2.2
Bnip1OLFOlfactory bulb7.94
5.54
Bnip1PPons1.05
1.16
Bnip1PALPallidum1.2
0.93
Bnip1RHPRetrohippocampal region8.82
5.66
Bnip1sAMYStriatum-like amygdalar nuclei0.74
0.83
Bnip1STRStriatum1.3
0.79
Bnip1STRdStriatum dorsal region1.54
0.92
Bnip1STRvStriatum ventral region1.16
0.61
Bnip1THThalamus1.13
0.86
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
SEC20_HUMAN_2 9 2 10 AAPQDVHVR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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