AutismKB 2.0

Annotation Detail for SNTB1


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Basic Information Top
Gene Symbol:SNTB1 ( 59-DAP,A1B,BSYN2,DAPA1B,FLJ22442,MGC111389,SNT2,SNT2B1,TIP-43 )
Gene Full Name: syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
Band: 8q24.12
Quick LinksEntrez ID:6641; OMIM: 600026; Uniprot ID:SNTB1_HUMAN; ENSEMBL ID: ENSG00000172164; HGNC ID: 11168
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus23 / 56401240
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor15 / 114246131
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor8 / 13630258
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor5 / 9635951
lung tumor1 / 1031279
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal77 / 336030722
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone1 / 7165513
bone marrow1 / 4880120
brain13 / 110098911
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye6 / 21105428
heart5 / 8962655
intestine17 / 23447272
kidney9 / 21177742
larynx0 / 241450 
liver15 / 20774372
lung7 / 33697420
lymph1 / 4427022
lymph node0 / 916100 
mammary gland2 / 15327113
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta4 / 28082514
prostate2 / 18934510
salivary gland1 / 2015549
skin2 / 2105749
spleen2 / 5395237
stomach1 / 9661910
testis2 / 3304426
thymus0 / 811310 
thyroid8 / 47473168
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208608_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.85
Adipocyte4.35
AdrenalCortex4.1
Adrenalgland4.75
Amygdala4.1
Appendix5
AtrioventricularNode3.05
BDCA4+_DentriticCells4.45
Bonemarrow3.9
BronchialEpithelialCells3.85
CD105+_Endothelial4
CD14+_Monocytes4.2
CD19+_BCells(neg._sel.)4.15
CD33+_Myeloid6.15
CD34+5
CD4+_Tcells4.25
CD56+_NKCells4.7
CD71+_EarlyErythroid3.7
CD8+_Tcells3.8
CardiacMyocytes5.2
Caudatenucleus3.55
Cerebellum3.2
CerebellumPeduncles4.45
CiliaryGanglion2.8
CingulateCortex4
Colorectaladenocarcinoma3.95
DorsalRootGanglion3.15
FetalThyroid3.8
Fetalbrain3.85
Fetalliver5.95
Fetallung3.2
GlobusPallidus2.9
Heart5.1
Hypothalamus4.25
Kidney3.45
Leukemia_chronicMyelogenousK-5623.55
Leukemia_promyelocytic-HL-603.45
Leukemialymphoblastic(MOLT-4)3.15
Liver5.25
Lung4.3
Lymphnode3.4
Lymphoma_burkitts(Daudi)5
Lymphoma_burkitts(Raji)5.55
MedullaOblongata3.95
OccipitalLobe3.55
OlfactoryBulb3.1
Ovary2.6
Pancreas3.2
PancreaticIslet4.2
ParietalLobe4.3
Pituitary4.6
Placenta4.05
Pons3.8
PrefrontalCortex4.85
Prostate4.55
Salivarygland3.5
SkeletalMuscle5.3
Skin3.1
SmoothMuscle4.45
Spinalcord4.2
SubthalamicNucleus3.55
SuperiorCervicalGanglion4.55
TemporalLobe3.55
Testis3.35
TestisGermCell3.25
TestisIntersitial3.3
TestisLeydigCell3.9
TestisSeminiferousTubule3.4
Thalamus4
Thymus3.1
Thyroid5
Tongue4.1
Tonsil3.8
Trachea3.3
TrigeminalGanglion4.3
Uterus3.2
UterusCorpus3.55
WholeBlood4.35
Wholebrain3.25
colon3.95
pineal_day4.96
pineal_night6.08
retina4.725
small_intestine3.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7520_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.37 ± 0.95
Basal Forebrain1.97 ± 0.39
Basal Part of Pons1.49 ± 0.33
Cerebellar Cortex1.63 ± 0.6
Cerebellar Nuclei2.02 ± 0.77
Claustrum2.65 ± 0.64
Epithalamus3.18 ± 0.76
Frontal Lobe1.78 ± 0.77
Globus Pallidus3.43 ± 0.7
Hypothalamus1.88 ± 0.67
Insula2.26 ± 0.72
Limbic Lobe1.82 ± 0.73
Mesencephalon2.18 ± 0.73
Myelencephalon1.98 ± 0.74
Occipital Lobe2.03 ± 0.64
Parietal Lobe1.89 ± 0.83
Pontine Tegmentum2.04 ± 0.83
Striatum2.57 ± 0.84
Subthalamus1.96 ± 0.78
Temporal Lobe1.78 ± 0.75
Thalamus2.05 ± 0.64
White Matter2 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sntb1CBCerebellum1.69
2.63
Sntb1CTXCerebral cortex1.61
1.52
Sntb1HIPHippocampal region1.74
1.67
Sntb1HPFHippocampal formation4.55
4.68
Sntb1HYHypothalamus0.83
0.71
Sntb1LSXLateral septal complex3.37
3.25
Sntb1MBMidbrain3.56
3.82
Sntb1MYMedulla4.7
4.92
Sntb1OLFOlfactory bulb3.3
3.02
Sntb1PPons2.07
2.16
Sntb1PALPallidum2.63
2.82
Sntb1RHPRetrohippocampal region8.33
7.95
Sntb1sAMYStriatum-like amygdalar nuclei2.62
2.71
Sntb1STRStriatum1.9
1.92
Sntb1STRdStriatum dorsal region1.38
1.55
Sntb1STRvStriatum ventral region1.92
1.67
Sntb1THThalamus8.49
7.73
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00433192 22 71 92 GAGAGHPGAGGAQPPDSPAGVR Peptide Atlas
SNTB1_HUMAN_1 18 1 18 AVAAAAAAAGPAGAGGGR PRIDE
SNTB1_HUMAN_2 18 2 19 AVAAAAAAAGPAGAGGGR PRIDE
SNTB1_HUMAN_264 16 264 279 QLEIHSPDAKHTVILR PRIDE
SNTB1_HUMAN_70 22 70 91 GAGAGHPGAGGAQPPDSPAGVR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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